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Mass Spectrometry Center

Located in I-court (I - 093) of the Health Sciences Building on the University of Washington campus (click here for directions), the Mass Spectrometry Center is a self-sustaining instrument laboratory providing a wide variety of mass spectral services to the University and the research community-at-large on a recharge basis. The Center serves as a resource offering analytical and instructional expertise in contemporary mass spectrometric techniques and instrumentation with the primary aim of providing investigators with "hands-on" training and ready access to "state-of-the-art" instrumentation needed to develop and meet their research interests. Examples of routine analysis are: Low and High Resolution mass analysis, metabolomics, Metid, analyte quantitation, and structural elucidation.

The Mass Spectrometry Center offers the following four categories of service:

  1. Submitted Sample Analysis ­ Routine analyses performed by Center personnel;
  2. Investigator Instrument Use ­ Instruction in the use and access to Center instrumentation by investigators; and
  3. Protocol Development ­ Contracted development of separations methodologies and mass spectral protocols.
  4. MRM Quantitative Proteomics  We can offer support on quantitative proteomics to the following projects: Protein quantification in tissues, cells, cell lines, biofluids.

Mass Spec Upcoming Events

Spring Quarter - Med Chem 541 (Biological Mass Spectrometry)

Publication Highlights

Nelson CH, Buttrick BR, Isoherranen N. "Therapeutic potential of the inhibition of the retinoic acid hydroxylases CYP26A1 and CYP26B1 by xenobiotics." Curr Top Med Chem. 2013; 13(12:1402-28). PubMed link.

Parkinson OT, Liggitt HD, Rettie AE, Kelly EJ. "Generalization and characterization of a CYP4B1 null mouse and the role of CYP4B1 in the activation and toxicity of Ipomeanol." Toxicol Sci. 2013 Aug; 134(2):243-50. PubMed link.

McDermott CL, Sandmaier BM, Storer B, Li H, Mager DE, Boeckh MJ, Bemer MJ, Knutson J, McCune JS. "Nonrelapse mortality and mycophenolic acid exposure in nonmyeloablative hematopoietic cell transplantation." Biol Blood Marrow Tranplant 2013 Aug; 19(8):1159-66. PubMed link.

Click here for complete list.