Faculty Publications
| PI Association | PMID | Publication Year | First Author | Title | Citation | DOI | Department | ||
|---|---|---|---|---|---|---|---|---|---|
| Nath | 39837577 | 2025 | Tuttle LM | Rigorous Analysis of Multimodal HDX-MS Spectra | J Am Soc Mass Spectrom. 2025 Feb 5;36(2):416-423. doi: 10.1021/jasms.4c00471. Epub 2025 Jan 21. | 10.1021/jasms.4c00471 | https://doi.org/10.1021/jasms.4c00471 | 4/28/26 | Medicinal Chemistry |
| Nath | 42541914 | 2026 | Authement AK | Modeling cortisol and cortisone binding to corticosteroid-binding globulin and albumin based on clinical protein binding data. | Drug Metab Dispos. 2026 Aug;54(8):100362. doi: 10.1016/j.dmd.2026.100362. Epub 2026 Jul 9. | 10.1016/j.dmd.2026.100362 | https://doi.org/10.1016/j.dmd.2026.100362 | 10/14/26 | Medicinal Chemistry |
| Nath | 42039475 | 2026 | Authement AK | Kinetics of cortisol and cortisone binding to corticosteroid binding globulin and albumin in vivo. | bioRxiv [Preprint]. 2026 Apr 17:2026.04.14.718600. doi: 10.64898/2026.04.14.718600. | 10.64898/2026.04.14.718600 | https://doi.org/10.64898/2026.04.14.718600 | 6/26/26 | Medicinal Chemistry |
| Nath | 41899522 | 2026 | Mariano IP | Biophysical and Structural Characterization of Antibody-Drug Conjugates | Cancers (Basel). 2026 Mar 12;18(6):917. doi: 10.3390/cancers18060917. | 10.3390/cancers18060917 | https://doi.org/10.3390/cancers18060917 | Medicinal Chemistry | |
| Nath | 38478383 | 2024 | Wiley AM | Investigating the association between CYP2J2 inhibitors and QT prolongation: a literature review | Drug Metab Rev. 2024 Feb-May;56(2):145-163. doi: 10.1080/03602532.2024.2329928. Epub 2024 Mar 20. | 10.1080/03602532.2024.2329928 | https://doi.org/10.1080/03602532.2024.2329928 | Medicinal Chemistry | |
| Nath | 35147406 | 2022 | Baggett DW | Structure-Activity Relationships of Novel Tau Ligands: Passive Fibril Binders and Active Aggregation Inhibitors | ACS Chem Biol. 2022 Mar 18;17(3):701-708. doi: 10.1021/acschembio.2c00012. Epub 2022 Feb 11. | 10.1021/acschembio.2c00012 | https://doi.org/10.1021/acschembio.2c00012 | Medicinal Chemistry | |
| Nath | 36194135 | 2022 | Kunk C | MitoNEET’s Reactivity of Lys55 toward Pyridoxal Phosphate Demonstrates its Activity as a Transaminase Enzyme | ACS Chem Biol. 2022 Oct 21;17(10):2716-2722. doi: 10.1021/acschembio.2c00572. Epub 2022 Oct 4. | 10.1021/acschembio.2c00572 | https://doi.org/10.1021/acschembio.2c00572 | Medicinal Chemistry | |
| Nath | 38352474 | 2024 | James EI | Tryptanthrin Analogs Substoichiometrically Inhibit Seeded and Unseeded Tau4RD Aggregation | bioRxiv [Preprint]. 2024 Feb 3:2024.02.02.578649. doi: 10.1101/2024.02.02.578649. | 10.1101/2024.02.02.578649 | https://doi.org/10.1101/2024.02.02.578649 | Medicinal Chemistry | |
| Nath | 37861473 | 2023 | Larsen HA | The origins of nonideality exhibited by monoclonal antibodies and Fab fragments in human serum | Protein Sci. 2023 Dec;32(12):e4812. doi: 10.1002/pro.4812. | 10.1002/pro.4812 | https://doi.org/10.1002/pro.4812 | Medicinal Chemistry | |
| Nath | 37562955 | 2023 | Alade N | The Utility of Mixed Effects Models in the Evaluation of Complex Genomic Traits In Vitro | Drug Metab Dispos. 2023 Nov;51(11):1455-1462. doi: 10.1124/dmd.123.001260. Epub 2023 Aug 10. | 10.1124/dmd.123.001260 | https://doi.org/10.1124/dmd.123.001260 | Medicinal Chemistry | |
| Nath | 36948348 | 2023 | Redhair M | Low molecular weight ligands bind to CYP3A4 via a branched induced fit mechanism: Implications for O(2) binding | Arch Biochem Biophys. 2023 May 1;739:109582. doi: 10.1016/j.abb.2023.109582. Epub 2023 Mar 21. | 10.1016/j.abb.2023.109582 | https://doi.org/10.1016/j.abb.2023.109582 | Medicinal Chemistry | |
| Nath | 34384764 | 2021 | Larsen HA | Probing interactions of therapeutic antibodies with serum via second virial coefficient measurements | Biophys J. 2021 Sep 21;120(18):4067-4078. doi: 10.1016/j.bpj.2021.08.007. Epub 2021 Aug 10. | 10.1016/j.bpj.2021.08.007 | https://doi.org/10.1016/j.bpj.2021.08.007 | Medicinal Chemistry | |
| Nath | 41279711 | 2025 | James EI | Tau4RD fibril polymorphism is imprinted during early aggregation | bioRxiv [Preprint]. 2025 Oct 14:2025.10.12.681486. doi: 10.1101/2025.10.12.681486. | 10.1101/2025.10.12.681486 | https://doi.org/10.1101/2025.10.12.681486 | Medicinal Chemistry | |
| Nath | 32814060 | 2020 | Vane EW | Rapid Formation of Peptide/Lipid Coaggregates by the Amyloidogenic Seminal Peptide PAP(248-286) | Biophys J. 2020 Sep 1;119(5):924-938. doi: 10.1016/j.bpj.2020.07.029. Epub 2020 Aug 6. | 10.1016/j.bpj.2020.07.029 | https://doi.org/10.1016/j.bpj.2020.07.029 | Medicinal Chemistry | |
| Nath | 31974309 | 2020 | Baughman HER | Release of a disordered domain enhances HspB1 chaperone activity toward tau | Proc Natl Acad Sci U S A. 2020 Feb 11;117(6):2923-2929. doi: 10.1073/pnas.1915099117. Epub 2020 Jan 23. | 10.1073/pnas.1915099117 | https://doi.org/10.1073/pnas.1915099117 | Medicinal Chemistry | |
| Nath | 33057715 | 2021 | Shen T | Identification of a novel tedizolid resistance mutation in rpoB of MRSA after in vitro serial passage | J Antimicrob Chemother. 2021 Jan 19;76(2):292-296. doi: 10.1093/jac/dkaa422. | 10.1093/jac/dkaa422 | https://doi.org/10.1093/jac/dkaa422 | Medicinal Chemistry | |
| Nath | 38293009 | 2024 | Yabut KCB | Drugs Form Ternary Complexes with Human Liver Fatty Acid Binding Protein (FABP1) and FABP1 Binding Alters Drug Metabolism | bioRxiv [Preprint]. 2024 Jan 19:2024.01.17.576032. doi: 10.1101/2024.01.17.576032. | 10.1101/2024.01.17.576032 | https://doi.org/10.1101/2024.01.17.576032 | Medicinal Chemistry | |
| Nath | 38580446 | 2024 | Yabut KCB | Drugs Form Ternary Complexes with Human Liver Fatty Acid Binding Protein 1 (FABP1) and FABP1 Binding Alters Drug Metabolism | Mol Pharmacol. 2024 May 17;105(6):395-410. doi: 10.1124/molpharm.124.000878. | 10.1124/molpharm.124.000878 | https://doi.org/10.1124/molpharm.124.000878 | Medicinal Chemistry | |
| Nath | 33161206 | 2021 | Sager JE | Corrigendum to “In vitro to in vivo extrapolation of the complex drug-drug interaction of bupropion and its metabolites with CYP2D6; simultaneous reversible inhibition and CYP2D6 downregulation” [Biochem. Pharmacol. 123(2017)85-96] | Biochem Pharmacol. 2021 Jan;183:114306. doi: 10.1016/j.bcp.2020.114306. Epub 2020 Nov 5. | 10.1016/j.bcp.2020.114306 | https://doi.org/10.1016/j.bcp.2020.114306 | Medicinal Chemistry | |
| Atkins | 31961139 | 2020 | Redhair M | Dynamics and Location of the Allosteric Midazolam Site in Cytochrome P4503A4 in Lipid Nanodiscs | Biochemistry. 2020 Feb 18;59(6):766-779. doi: 10.1021/acs.biochem.9b01001. Epub 2020 Jan 27. | 10.1021/acs.biochem.9b01001 | https://doi.org/10.1021/acs.biochem.9b01001 | Medicinal Chemistry | |
| Atkins | 31982812 | 2020 | Lockart MM | Multiple drug binding modes in Mycobacterium tuberculosis CYP51B1 | J Inorg Biochem. 2020 Apr;205:110994. doi: 10.1016/j.jinorgbio.2020.110994. Epub 2020 Jan 13. | 10.1016/j.jinorgbio.2020.110994 | https://doi.org/10.1016/j.jinorgbio.2020.110994 | Medicinal Chemistry | |
| Atkins | 32786398 | 2020 | Paço L | Dynamics and Mechanism of Binding of Androstenedione to Membrane-Associated Aromatase | Biochemistry. 2020 Aug 25;59(33):2999-3009. doi: 10.1021/acs.biochem.0c00460. Epub 2020 Aug 11. | 10.1021/acs.biochem.0c00460 | https://doi.org/10.1021/acs.biochem.0c00460 | Medicinal Chemistry | |
| Atkins | 33350827 | 2021 | Clouser AF | Cholesterol Asymmetrically Modulates the Conformational Ensemble of the Nucleotide-Binding Domains of P-Glycoprotein in Lipid Nanodiscs | Biochemistry. 2021 Jan 12;60(1):85-94. doi: 10.1021/acs.biochem.0c00824. Epub 2020 Dec 22. | 10.1021/acs.biochem.0c00824 | https://doi.org/10.1021/acs.biochem.0c00824 | Medicinal Chemistry | |
| Atkins | 34715072 | 2021 | Redhair M | Analytical and functional aspects of protein-ligand interactions: Beyond induced fit and conformational selection | Arch Biochem Biophys. 2021 Dec 15;714:109064. doi: 10.1016/j.abb.2021.109064. Epub 2021 Oct 26. | 10.1016/j.abb.2021.109064 | https://doi.org/10.1016/j.abb.2021.109064 | Medicinal Chemistry | |
| Atkins | 35384651 | 2022 | Clouser AF | Long Range Communication between the Drug-Binding Sites and Nucleotide Binding Domains of the Efflux Transporter ABCB1 | Biochemistry. 2022 Apr 19;61(8):730-740. doi: 10.1021/acs.biochem.2c00056. Epub 2022 Apr 6. | 10.1021/acs.biochem.2c00056 | https://doi.org/10.1021/acs.biochem.2c00056 | Medicinal Chemistry | |
| Atkins | 37080138 | 2023 | Paço L | Nanodisc-embedded cytochrome P450 P3A4 binds diverse ligands by distributing conformational dynamics to its flexible elements | J Inorg Biochem. 2023 Jul;244:112211. doi: 10.1016/j.jinorgbio.2023.112211. Epub 2023 Apr 5. | 10.1016/j.jinorgbio.2023.112211 | https://doi.org/10.1016/j.jinorgbio.2023.112211 | Medicinal Chemistry | |
| Atkins | 36948348 | 2023 | Redhair M | Low molecular weight ligands bind to CYP3A4 via a branched induced fit mechanism: Implications for O(2) binding | Arch Biochem Biophys. 2023 May 1;739:109582. doi: 10.1016/j.abb.2023.109582. Epub 2023 Mar 21. | 10.1016/j.abb.2023.109582 | https://doi.org/10.1016/j.abb.2023.109582 | Medicinal Chemistry | |
| Atkins | 31173761 | 2020 | Goulet DR | Considerations for the Design of Antibody-Based Therapeutics | J Pharm Sci. 2020 Jan;109(1):74-103. doi: 10.1016/j.xphs.2019.05.031. Epub 2019 Jun 4. | 10.1016/j.xphs.2019.05.031 | https://doi.org/10.1016/j.xphs.2019.05.031 | Medicinal Chemistry | |
| Atkins | 31702857 | 2020 | Goulet DR | Design and characterization of novel dual Fc antibody with enhanced avidity for Fc receptors | Proteins. 2020 May;88(5):689-697. doi: 10.1002/prot.25853. Epub 2019 Nov 20. | 10.1002/prot.25853 | https://doi.org/10.1002/prot.25853 | Medicinal Chemistry | |
| Atkins | 34383776 | 2021 | Kachapila M | Preliminary model assessing the cost-effectiveness of preoperative chlorhexidine mouthwash at reducing postoperative pneumonia among abdominal surgery patients in South Africa | PLoS One. 2021 Aug 12;16(8):e0254698. doi: 10.1371/journal.pone.0254698. eCollection 2021. | 10.1371/journal.pone.0254698 | https://doi.org/10.1371/journal.pone.0254698 | Medicinal Chemistry | |
| Atkins | 34384764 | 2021 | Larsen HA | Probing interactions of therapeutic antibodies with serum via second virial coefficient measurements | Biophys J. 2021 Sep 21;120(18):4067-4078. doi: 10.1016/j.bpj.2021.08.007. Epub 2021 Aug 10. | 10.1016/j.bpj.2021.08.007 | https://doi.org/10.1016/j.bpj.2021.08.007 | Medicinal Chemistry | |
| Atkins | 34871379 | 2021 | STARSurg Collaborative and COVIDSurg Collaborative | Death following pulmonary complications of surgery before and during the SARS-CoV-2 pandemic | Br J Surg. 2021 Dec 1;108(12):1448-1464. doi: 10.1093/bjs/znab336. | 10.1093/bjs/znab336 | https://doi.org/10.1093/bjs/znab336 | Medicinal Chemistry | |
| Atkins | 35750401 | 2022 | STARSurg Collaborative and TASMAN Collaborative | Evaluation of prognostic risk models for postoperative pulmonary complications in adult patients undergoing major abdominal surgery: a systematic review and international external validation cohort study | Lancet Digit Health. 2022 Jul;4(7):e520-e531. doi: 10.1016/S2589-7500(22)00069-3. | 10.1016/S2589-7500(22)00069-3 | https://doi.org/10.1016/S2589-7500(22)00069-3 | Medicinal Chemistry | |
| Atkins | 31663687 | 2020 | Atkins WM | Mechanisms of promiscuity among drug metabolizing enzymes and drug transporters | FEBS J. 2020 Apr;287(7):1306-1322. doi: 10.1111/febs.15116. Epub 2019 Nov 12. | 10.1111/febs.15116 | https://doi.org/10.1111/febs.15116 | Medicinal Chemistry | |
| Atkins | 36830698 | 2023 | Scian M | Reversibility and Low Commitment to Forward Catalysis in the Conjugation of Lipid Alkenals by Glutathione Transferase A4-4 | Biomolecules. 2023 Feb 9;13(2):329. doi: 10.3390/biom13020329. | 10.3390/biom13020329 | https://doi.org/10.3390/biom13020329 | Medicinal Chemistry | |
| Atkins | 37861473 | 2023 | Larsen HA | The origins of nonideality exhibited by monoclonal antibodies and Fab fragments in human serum | Protein Sci. 2023 Dec;32(12):e4812. doi: 10.1002/pro.4812. | 10.1002/pro.4812 | https://doi.org/10.1002/pro.4812 | Medicinal Chemistry | |
| Bhardwaj | 42395444 | 2026 | Srinivas P | Orally available designed miniproteins inhibit enterotoxigenic Bacteroides fragilis pathology by blocking toxin receptor binding | bioRxiv [Preprint]. 2026 Jun 23:2026.06.22.733822. doi: 10.64898/2026.06.22.733822. | 10.64898/2026.06.22.733822 | https://doi.org/10.64898/2026.06.22.733822 | 10/14/26 | Medicinal Chemistry |
| Bhardwaj | 42056544 | 2026 | Yang W | The past, present and future of de novo protein design. | Nature. 2026 Apr;652(8112):1139-1152. doi: 10.1038/s41586-026-10328-7. Epub 2026 Apr 29. | 10.1038/s41586-026-10328-7 | https://doi.org/10.1038/s41586-026-10328-7 | 6/26/26 | Medicinal Chemistry |
| Bhardwaj | 42056544 | 2026 | Yang W | The past, present and future of de novo protein design | Nature. 2026 Apr;652(8112):1139-1152. doi: 10.1038/s41586-026-10328-7. Epub 2026 Apr 29. | 10.1038/s41586-026-10328-7 | https://doi.org/10.1038/s41586-026-10328-7 | Medicinal Chemistry | |
| Bhardwaj | 41818167 | 2026 | Luxford JC, | Mixed Autoimmune Hemolytic Anemia With Refractory Cold Agglutinin Syndrome in a Child Successfully Treated With Serial Whole Blood Exchange Transfusions and Immunosuppression | J Pediatr Hematol Oncol. 2026 Apr 1;48(3):e128-e133. doi: 10.1097/MPH.0000000000003180. Epub 2026 Mar 2. | 10.1097/MPH.0000000000003180 | https://doi.org/10.1097/MPH.0000000000003180 | 4/28/26 | Medicinal Chemistry |
| Bhardwaj | 41779186 | 2026 | Wankhede L | Integrated one-pot ultrasound-assisted method for carotenoid extraction from Rhodosporidium toruloides | Wankhede L, Bhardwaj G, Osorio-González CS, Brar SK. Integrated one-pot ultrasound-assisted method for carotenoid extraction from Rhodosporidium toruloides. Bioprocess Biosyst Eng. 2026 Mar 4. doi: 10.1007/s00449-026-03299-6. Epub ahead of print. | 10.1007/s00449-026-03299-6 | https://doi.org/10.1007/s00449-026-03299-6 | 4/28/26 | Medicinal Chemistry |
| Bhardwaj | 36384286 | 2023 | Manna P | Accommodative spasm and its different treatment approaches: A systematic review | Eur J Ophthalmol. 2023 May;33(3):1273-1286. doi: 10.1177/11206721221136438. Epub 2022 Nov 16. | 10.1177/11206721221136438 | https://doi.org/10.1177/11206721221136438 | Medicinal Chemistry | |
| Bhardwaj | 36041435 | 2022 | Bhardwaj G | Accurate de novo design of membrane-traversing macrocycles | Cell. 2022 Sep 15;185(19):3520-3532.e26. doi: 10.1016/j.cell.2022.07.019. Epub 2022 Aug 29. | 10.1016/j.cell.2022.07.019 | https://doi.org/10.1016/j.cell.2022.07.019 | Medicinal Chemistry | |
| Bhardwaj | 36865323 | 2023 | Rettie SA | Cyclic peptide structure prediction and design using AlphaFold | bioRxiv [Preprint]. 2023 Feb 26:2023.02.25.529956. doi: 10.1101/2023.02.25.529956. | 10.1101/2023.02.25.529956 | https://doi.org/10.1101/2023.02.25.529956 | Medicinal Chemistry | |
| Bhardwaj | 39605685 | 2024 | Rettie SA | Accurate de novo design of high-affinity protein binding macrocycles using deep learning | bioRxiv [Preprint]. 2024 Nov 18:2024.11.18.622547. doi: 10.1101/2024.11.18.622547. | 10.1101/2024.11.18.622547 | https://doi.org/10.1101/2024.11.18.622547 | Medicinal Chemistry | |
| Bhardwaj | 40542165 | 2025 | Rettie SA | Accurate de novo design of high-affinity protein-binding macrocycles using deep learning | Nat Chem Biol. 2025 Dec;21(12):1948-1956. doi: 10.1038/s41589-025-01929-w. Epub 2025 Jun 20. | 10.1038/s41589-025-01929-w | https://doi.org/10.1038/s41589-025-01929-w | Medicinal Chemistry | |
| Bhardwaj | 39525204 | 2024 | Mahajan BB | Bilastine Reimagined: A Comprehensive Exploration of Pruritus Management With a Novel Antihistamine | Cureus. 2024 Oct 10;16(10):e71232. doi: 10.7759/cureus.71232. eCollection 2024 Oct. | 10.7759/cureus.71232 | https://doi.org/10.7759/cureus.71232 | Medicinal Chemistry | |
| Bhardwaj | 38052802 | 2023 | MuratspahiÄ E | Design and structural validation of peptide-drug conjugate ligands of the kappa-opioid receptor | Nat Commun. 2023 Dec 6;14(1):8064. doi: 10.1038/s41467-023-43718-w. | 10.1038/s41467-023-43718-w | https://doi.org/10.1038/s41467-023-43718-w | Medicinal Chemistry | |
| Bhardwaj | 40399308 | 2025 | Rettie SA | Cyclic peptide structure prediction and design using AlphaFold2 | Nat Commun. 2025 May 21;16(1):4730. doi: 10.1038/s41467-025-59940-7. | 10.1038/s41467-025-59940-7 | https://doi.org/10.1038/s41467-025-59940-7 | Medicinal Chemistry | |
| Bhardwaj | 39618904 | 2024 | Mondal A | Binocular Vision Status in Coal Miners | Indian J Occup Environ Med. 2024 Jul-Sep;28(3):194-197. doi: 10.4103/ijoem.ijoem_137_23. Epub 2024 Sep 30. | 10.4103/ijoem.ijoem_137_23 | https://doi.org/10.4103/ijoem.ijoem_137_23 | Medicinal Chemistry | |
| Bhardwaj | 37178478 | 2023 | Ramelot TA | Cell-permeable chameleonic peptides: Exploiting conformational dynamics in de novo cyclic peptide design | Curr Opin Struct Biol. 2023 Jun;80:102603. doi: 10.1016/j.sbi.2023.102603. Epub 2023 May 12. | 10.1016/j.sbi.2023.102603 | https://doi.org/10.1016/j.sbi.2023.102603 | Medicinal Chemistry | |
| Bhardwaj | 39032267 | 2024 | Wankhede L | Technological modes and processes to enhance the Rhodosporidium toruloides based lipid accumulation | Microbiol Res. 2024 Oct;287:127840. doi: 10.1016/j.micres.2024.127840. Epub 2024 Jul 16. | 10.1016/j.micres.2024.127840 | https://doi.org/10.1016/j.micres.2024.127840 | Medicinal Chemistry | |
| Bhardwaj | 35112543 | 2021 | Naredi M | Diabetic myonecrosis in end-stage renal disease | Natl Med J India. 2021 Jul-Aug;34(4):206-210. doi: 10.25259/NMJI_191_19. | 10.25259/NMJI_191_19 | https://doi.org/10.25259/NMJI_191_19 | Medicinal Chemistry | |
| Bhardwaj | 38662830 | 2024 | Salveson PJ | Expansive discovery of chemically diverse structured macrocyclic oligoamides | Science. 2024 Apr 26;384(6694):420-428. doi: 10.1126/science.adk1687. Epub 2024 Apr 25. | 10.1126/science.adk1687 | https://doi.org/10.1126/science.adk1687 | Medicinal Chemistry | |
| Bhardwaj | 41117072 | 2025 | Gokce-Alpkilic G | De Novo Design of High-Affinity Miniprotein Binders Targeting Francisella Tularensis Virulence Factor | Angew Chem Int Ed Engl. 2025 Dec 22;64(52):e202516058. doi: 10.1002/anie.202516058. Epub 2025 Oct 21. | 10.1002/anie.202516058 | https://doi.org/10.1002/anie.202516058 | Medicinal Chemistry | |
| Bhardwaj | 40631088 | 2025 | Gokce-Alpkilic G | De novo design of high-affinity miniprotein binders targeting Francisella tularensis virulence factor | bioRxiv [Preprint]. 2025 Jul 5:2025.07.02.662053. doi: 10.1101/2025.07.02.662053. | 10.1101/2025.07.02.662053 | https://doi.org/10.1101/2025.07.02.662053 | Medicinal Chemistry | |
| Bhardwaj | 37780187 | 2023 | Azam R | The Effect of Illumination on Positive Fusional Vergence | Br Ir Orthopt J. 2023 Sep 29;19(1):78-84. doi: 10.22599/bioj.296. eCollection 2023. | 10.22599/bioj.296 | https://doi.org/10.22599/bioj.296 | Medicinal Chemistry | |
| Bhardwaj | 39154992 | 2024 | Mathew J | Innovating Ferro-sonication approach for extracting microplastics from wastewater | Sci Total Environ. 2024 Nov 15;951:175595. doi: 10.1016/j.scitotenv.2024.175595. Epub 2024 Aug 16. | 10.1016/j.scitotenv.2024.175595 | https://doi.org/10.1016/j.scitotenv.2024.175595 | Medicinal Chemistry | |
| Bhardwaj | 40357425 | 2025 | Schumacher I | Performance analysis of an emergency triage system in ophthalmology using a customized CHATBOT | Digit Health. 2025 May 11;11:20552076251320298. doi: 10.1177/20552076251320298. eCollection 2025 Jan-Dec. | 10.1177/20552076251320298 | https://doi.org/10.1177/20552076251320298 | Medicinal Chemistry | |
| Bhardwaj | 38712757 | 2024 | Craven TW | Computational Design of Cyclic Peptide Inhibitors of a Bacterial Membrane Lipoprotein Peptidase | ACS Chem Biol. 2024 May 17;19(5):1125-1130. doi: 10.1021/acschembio.4c00076. Epub 2024 May 7. | 10.1021/acschembio.4c00076 | https://doi.org/10.1021/acschembio.4c00076 | Medicinal Chemistry | |
| Bhardwaj | 38529717 | 2024 | Bruce A | A Tag-Free Platform for Synthesis and Screening of Cyclic Peptide Libraries | Angew Chem Int Ed Engl. 2024 May 21;63(21):e202320045. doi: 10.1002/anie.202320045. Epub 2024 Apr 17. | 10.1002/anie.202320045 | https://doi.org/10.1002/anie.202320045 | Medicinal Chemistry | |
| Bhardwaj | 40666773 | 2025 | Karmakar S | Cognitive decline, dual sensory loss and the use of visual aids in elderly – A narrative review | Oman J Ophthalmol. 2025 Jun 24;18(2):113-120. doi: 10.4103/ojo.ojo_177_23. eCollection 2025 May-Aug. | 10.4103/ojo.ojo_177_23 | https://doi.org/10.4103/ojo.ojo_177_23 | Medicinal Chemistry | |
| Bhardwaj | 32195445 | 2020 | Bloch E | Scleral perforation involving the papillomacular bundle secondary to peribulbar anaesthetic injection | Am J Ophthalmol Case Rep. 2020 Mar 11;18:100657. doi: 10.1016/j.ajoc.2020.100657. eCollection 2020 Jun. | 10.1016/j.ajoc.2020.100657 | https://doi.org/10.1016/j.ajoc.2020.100657 | Medicinal Chemistry | |
| Bhardwaj | 32734467 | 2021 | Anguita R | Clinical presentations and surgical outcomes of intraocular foreign body presenting to an ocular trauma unit | Graefes Arch Clin Exp Ophthalmol. 2021 Jan;259(1):263-268. doi: 10.1007/s00417-020-04859-6. Epub 2020 Jul 30. | 10.1007/s00417-020-04859-6 | https://doi.org/10.1007/s00417-020-04859-6 | Medicinal Chemistry | |
| Bhardwaj | 39406662 | 2024 | Mathew J | Corrigendum to “Innovating Ferro-sonication approach for extracting microplastics from wastewater” [Sci. Total Environ. (2024) 1-9, 175595] | Sci Total Environ. 2024 Dec 1;954:176771. doi: 10.1016/j.scitotenv.2024.176771. Epub 2024 Oct 15. | 10.1016/j.scitotenv.2024.176771 | https://doi.org/10.1016/j.scitotenv.2024.176771 | Medicinal Chemistry | |
| Bhardwaj | 30576303 | 2020 | Bhardwaj G | MANAGEMENT OF GIANT RETINAL TEARS USING TRANSSCLERAL DIODE LASER RETINOPEXY AND SHORT-TERM POSTOPERATIVE TAMPONADE WITH PERFLUORO-N-OCTANE | Retina. 2020 Mar;40(3):546-551. doi: 10.1097/IAE.0000000000002424. | 10.1097/IAE.0000000000002424 | https://doi.org/10.1097/IAE.0000000000002424 | Medicinal Chemistry | |
| Bhardwaj | 39254187 | 2025 | Manna P | Effects of Two Vision Therapy Approaches on Accommodative Insufficiency and Post-therapy Stability | J Pediatr Ophthalmol Strabismus. 2025 Jan-Feb;62(1):12-26. doi: 10.3928/01913913-20240807-01. Epub 2024 Sep 10. | 10.3928/01913913-20240807-01 | https://doi.org/10.3928/01913913-20240807-01 | Medicinal Chemistry | |
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| Rettie | 40932355 | 2025 | Fiume MM | Re-Review Summary of PEG Stearates as Used in Cosmetics | Int J Toxicol. 2025 Oct;44(3_suppl):100S-116S. doi: 10.1177/10915818251359230. Epub 2025 Sep 11. | 10.1177/10915818251359230 | https://doi.org/10.1177/10915818251359230 | Medicinal Chemistry | |
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| Xu | 41822371 | 2026 | Stohs EJ | Emergence of Dalbavancin, Vancomycin, and Daptomycin Cross-resistance in MRSA During Long-term LVAD Suppression With Vancomycin Followed by Dalbavancin: Genomic Insights and Synergy With Cefadroxil | Open Forum Infect Dis. 2026 Feb 16;13(3):ofag074. doi: 10.1093/ofid/ofag074. | 10.1093/ofid/ofag074 | https://doi.org/10.1093/ofid/ofag074 | 4/28/26 | Medicinal Chemistry |
| Xu | 41820720 | 2026 | Cheng R, | Assessing the Recovery of Muscle Fatigue Using Shear Wave Elastography | Sports Med Open. 2026 Mar 12;12(1):30. doi: 10.1186/s40798-026-00991-5. | 10.1186/s40798-026-00991-5 | https://doi.org/10.1186/s40798-026-00991-5 | 4/28/26 | Medicinal Chemistry |
| Xu | 41793791 | 2026 | Xu L | KLK8 promotes cartilage degradation and pyroptosis in osteoarthritis by activating the NF-κB and NLRP3 inflammasome pathways | Tissue Cell. 2026 Feb 27;101:103427. doi: 10.1016/j.tice.2026.103427. Epub ahead of print. | 10.1016/j.tice.2026.103427 | https://doi.org/10.1016/j.tice.2026.103427 | 4/28/26 | Medicinal Chemistry |
| Xu | 40140573 | 2025 | Ha YJ | The contribution of de novo coding mutations to meningomyelocele | Nature. 2025 May;641(8062):419-426. doi: 10.1038/s41586-025-08676-x. Epub 2025 Mar 26. | 10.1038/s41586-025-08676-x | https://doi.org/10.1038/s41586-025-08676-x | Medicinal Chemistry | |
| Xu | 37157132 | 2023 | Arnold WA | Quaternary Ammonium Compounds: A Chemical Class of Emerging Concern | Environ Sci Technol. 2023 May 23;57(20):7645-7665. doi: 10.1021/acs.est.2c08244. Epub 2023 May 8. | 10.1021/acs.est.2c08244 | https://doi.org/10.1021/acs.est.2c08244 | Medicinal Chemistry | |
| Xu | 39405116 | 2024 | Nguyen AH | Molecular basis of cell membrane adaptation in daptomycin-resistant Enterococcus faecalis | JCI Insight. 2024 Nov 22;9(22):e173836. doi: 10.1172/jci.insight.173836. | 10.1172/jci.insight.173836 | https://doi.org/10.1172/jci.insight.173836 | Medicinal Chemistry | |
| Xu | 33736803 | 2021 | Ross DH | Determination of drugs and drug metabolites by ion mobility-mass spectrometry: A review | Anal Chim Acta. 2021 Apr 15;1154:338270. doi: 10.1016/j.aca.2021.338270. Epub 2021 Feb 2. | 10.1016/j.aca.2021.338270 | https://doi.org/10.1016/j.aca.2021.338270 | Medicinal Chemistry | |
| Xu | 36111785 | 2022 | Tomita H | 7-Dehydrocholesterol-derived oxysterols cause neurogenic defects in Smith-Lemli-Opitz syndrome | Elife. 2022 Sep 16;11:e67141. doi: 10.7554/eLife.67141. | 10.7554/eLife.67141 | https://doi.org/10.7554/eLife.67141 | Medicinal Chemistry | |
| Xu | 40133959 | 2025 | Li J | Radiation-induced ferroptosis via liposomal delivery of 7-Dehydrocholesterol | J Nanobiotechnology. 2025 Mar 26;23(1):249. doi: 10.1186/s12951-025-03303-3. | 10.1186/s12951-025-03303-3 | https://doi.org/10.1186/s12951-025-03303-3 | Medicinal Chemistry | |
| Xu | 38077958 | 2023 | Elias ER | Cholic acid increases plasma cholesterol in Smith-Lemli-Opitz syndrome: A pilot study | Mol Genet Metab Rep. 2023 Nov 28;38:101030. doi: 10.1016/j.ymgmr.2023.101030. eCollection 2024 Mar. | 10.1016/j.ymgmr.2023.101030 | https://doi.org/10.1016/j.ymgmr.2023.101030 | Medicinal Chemistry | |
| Xu | 33284321 | 2021 | Findakly S | Sterol and oxysterol synthases near the ciliary base activate the Hedgehog pathway | J Cell Biol. 2021 Jan 4;220(1):e202002026. doi: 10.1083/jcb.202002026. | 10.1083/jcb.202002026 | https://doi.org/10.1083/jcb.202002026 | Medicinal Chemistry | |
| Xu | 35548857 | 2022 | Ross DH | High-Throughput Measurement and Machine Learning-Based Prediction of Collision Cross Sections for Drugs and Drug Metabolites | J Am Soc Mass Spectrom. 2022 Jun 1;33(6):1061-1072. doi: 10.1021/jasms.2c00111. Epub 2022 May 11. | 10.1021/jasms.2c00111 | https://doi.org/10.1021/jasms.2c00111 | Medicinal Chemistry | |
| Xu | 38322411 | 2023 | Do Q | How do different lipid peroxidation mechanisms contribute to ferroptosis? | Cell Rep Phys Sci. 2023 Dec 20;4(12):101683. doi: 10.1016/j.xcrp.2023.101683. Epub 2023 Nov 17. | 10.1016/j.xcrp.2023.101683 | https://doi.org/10.1016/j.xcrp.2023.101683 | Medicinal Chemistry | |
| Xu | 39276938 | 2024 | Hass DT | Acetyl-CoA carboxylase inhibition increases retinal pigment epithelial cell fatty acid flux and restricts apolipoprotein efflux | J Biol Chem. 2024 Oct;300(10):107772. doi: 10.1016/j.jbc.2024.107772. Epub 2024 Sep 12. | 10.1016/j.jbc.2024.107772 | https://doi.org/10.1016/j.jbc.2024.107772 | Medicinal Chemistry | |
| Xu | 38307853 | 2024 | Vieira LS | Interaction and Transport of Benzalkonium Chlorides by the Organic Cation and Multidrug and Toxin Extrusion Transporters | Drug Metab Dispos. 2024 Mar 13;52(4):312-321. doi: 10.1124/dmd.123.001625. | 10.1124/dmd.123.001625 | https://doi.org/10.1124/dmd.123.001625 | Medicinal Chemistry | |
| Xu | 37124288 | 2023 | Do Q | Differential Contributions of Distinct Free Radical Peroxidation Mechanisms to the Induction of Ferroptosis | JACS Au. 2023 Mar 4;3(4):1100-1117. doi: 10.1021/jacsau.2c00681. eCollection 2023 Apr 24. | 10.1021/jacsau.2c00681 | https://doi.org/10.1021/jacsau.2c00681 | Medicinal Chemistry | |
| Xu | 37425828 | 2023 | Pruitt EL | Elucidating the Impact of Bacterial Lipases, Human Serum Albumin, and FASII Inhibition on the Utilization of Exogenous Fatty Acids by Staphylococcus aureus | bioRxiv [Preprint]. 2023 Jun 30:2023.06.29.547085. doi: 10.1101/2023.06.29.547085. | 10.1101/2023.06.29.547085 | https://doi.org/10.1101/2023.06.29.547085 | Medicinal Chemistry | |
| Xu | 35504891 | 2022 | Lo M | CNPY4 inhibits the Hedgehog pathway by modulating membrane sterol lipids | Nat Commun. 2022 May 3;13(1):2407. doi: 10.1038/s41467-022-30186-x. | 10.1038/s41467-022-30186-x | https://doi.org/10.1038/s41467-022-30186-x | Medicinal Chemistry | |
| Xu | 38534032 | 2024 | Nguyen R | Development and Application of a Multidimensional Database for the Detection of Quaternary Ammonium Compounds and Their Phase I Hepatic Metabolites in Humans | Environ Sci Technol. 2024 Apr 9;58(14):6236-6249. doi: 10.1021/acs.est.3c10845. Epub 2024 Mar 27. | 10.1021/acs.est.3c10845 | https://doi.org/10.1021/acs.est.3c10845 | Medicinal Chemistry | |
| Xu | 37523294 | 2023 | Reimers N | Tracking the Metabolic Fate of Exogenous Arachidonic Acid in Ferroptosis Using Dual-Isotope Labeling Lipidomics | J Am Soc Mass Spectrom. 2023 Sep 6;34(9):2016-2024. doi: 10.1021/jasms.3c00181. Epub 2023 Jul 31. | 10.1021/jasms.3c00181 | https://doi.org/10.1021/jasms.3c00181 | Medicinal Chemistry | |
| Xu | 37535099 | 2023 | Zhang R | High-throughput analysis of lipidomic phenotypes of methicillin-resistant Staphylococcus aureus by coupling in situ 96-well cultivation and HILIC-ion mobility-mass spectrometry | Anal Bioanal Chem. 2023 Oct;415(25):6191-6199. doi: 10.1007/s00216-023-04890-6. Epub 2023 Aug 3. | 10.1007/s00216-023-04890-6 | https://doi.org/10.1007/s00216-023-04890-6 | Medicinal Chemistry | |
| Xu | 35293916 | 2022 | Li A | Temporal changes in the brain lipidome during neurodevelopment of Smith-Lemli-Opitz syndrome mice | Analyst. 2022 Apr 11;147(8):1611-1621. doi: 10.1039/d2an00137c. | 10.1039/d2an00137c | https://doi.org/10.1039/d2an00137c | Medicinal Chemistry | |
| Xu | 39363503 | 2024 | Lopez VA | Oral exposure to benzalkonium chlorides in male and female mice reveals alteration of the gut microbiome and bile acid profile | Toxicol Sci. 2024 Dec 1;202(2):265-277. doi: 10.1093/toxsci/kfae116. | 10.1093/toxsci/kfae116 | https://doi.org/10.1093/toxsci/kfae116 | Medicinal Chemistry | |
| Xu | 41388019 | 2025 | Chac D | Nat Commun. 2025 Dec 12. doi: 10.1038/s41467-025-67388-y. Online ahead of print. | 10.1038/s41467-025-67388-y | https://doi.org/10.1038/s41467-025-67388-y | Medicinal Chemistry | ||
| Xu | 38014966 | 2023 | Pruitt EL | Â 42736259Â | mSphere. 2023 Dec 20;8(6):e0036823. doi: 10.1128/msphere.00368-23. Epub 2023 Nov 28. | 10.1128/msphere.00368-23 | https://doi.org/10.1128/msphere.00368-23 | Medicinal Chemistry | |
| Xu | 41366203 | 2025 | Zhao HN | A resource to empirically establish drug exposure records directly from untargeted metabolomics data | Nat Commun. 2025 Dec 9;16(1):10600. doi: 10.1038/s41467-025-65993-5. | 10.1038/s41467-025-65993-5 | https://doi.org/10.1038/s41467-025-65993-5 | Medicinal Chemistry | |
| Xu | 39416075 | 2024 | Zhao HN | Empirically establishing drug exposure records directly from untargeted metabolomics data | bioRxiv [Preprint]. 2024 Oct 26:2024.10.07.617109. doi: 10.1101/2024.10.07.617109. | 10.1101/2024.10.07.617109 | https://doi.org/10.1101/2024.10.07.617109 | Medicinal Chemistry | |
| Xu | 35175195 | 2022 | Ting SY | Discovery of coordinately regulated pathways that provide innate protection against interbacterial antagonism | Elife. 2022 Feb 17;11:e74658. doi: 10.7554/eLife.74658. | 10.7554/eLife.74658 | https://doi.org/10.7554/eLife.74658 | Medicinal Chemistry | |
| Xu | 39192580 | 2024 | Weakly HMJ | Several common methods of making vesicles (except an emulsion method) capture intended lipid ratios | Biophys J. 2024 Oct 1;123(19):3452-3462. doi: 10.1016/j.bpj.2024.08.019. Epub 2024 Aug 26. | 10.1016/j.bpj.2024.08.019 | https://doi.org/10.1016/j.bpj.2024.08.019 | Medicinal Chemistry | |
| Xu | 33652836 | 2021 | Pfeffer BA | Transcriptomic Changes Associated with Loss of Cell Viability Induced by Oxysterol Treatment of a Retinal Photoreceptor-Derived Cell Line: An In Vitro Model of Smith-Lemli-Opitz Syndrome | Int J Mol Sci. 2021 Feb 26;22(5):2339. doi: 10.3390/ijms22052339. | 10.3390/ijms22052339 | https://doi.org/10.3390/ijms22052339 | Medicinal Chemistry | |
| Xu | 38746422 | 2024 | Raskovic D | Growth of Staphylococcus aureus in the presence of oleic acid shifts the glycolipid fatty acid profile and increases resistance to antimicrobial peptides | bioRxiv [Preprint]. 2024 May 5:2024.05.03.592415. doi: 10.1101/2024.05.03.592415. | 10.1101/2024.05.03.592415 | https://doi.org/10.1101/2024.05.03.592415 | Medicinal Chemistry | |
| Xu | 37577529 | 2023 | Daggubati V | Hedgehog target genes regulate lipid metabolism to drive basal cell carcinoma and medulloblastoma | Res Sq [Preprint]. 2023 Aug 3:rs.3.rs-3058335. doi: 10.21203/rs.3.rs-3058335/v1. | 10.21203/rs.3.rs-3058335/v1 | https://doi.org/10.21203/rs.3.rs-3058335/v1 | Medicinal Chemistry | |
| Xu | 33868951 | 2021 | Hrubec TC | Altered toxicological endpoints in humans from common quaternary ammonium compound disinfectant exposure | Toxicol Rep. 2021 Mar 9;8:646-656. doi: 10.1016/j.toxrep.2021.03.006. eCollection 2021. | 10.1016/j.toxrep.2021.03.006 | https://doi.org/10.1016/j.toxrep.2021.03.006 | Medicinal Chemistry | |
| Xu | 33476305 | 2021 | Daggubati V | Smoothened-activating lipids drive resistance to CDK4/6 inhibition in Hedgehog-associated medulloblastoma cells and preclinical models | J Clin Invest. 2021 Mar 15;131(6):e141171. doi: 10.1172/JCI141171. | 10.1172/JCI141171 | https://doi.org/10.1172/JCI141171 | Medicinal Chemistry | |
| Xu | 33057715 | 2021 | Shen T | Identification of a novel tedizolid resistance mutation in rpoB of MRSA after in vitro serial passage | J Antimicrob Chemother. 2021 Jan 19;76(2):292-296. doi: 10.1093/jac/dkaa422. | 10.1093/jac/dkaa422 | https://doi.org/10.1093/jac/dkaa422 | Medicinal Chemistry | |
| Xu | 34646861 | 2021 | Zhang R | Synergy Between Beta-Lactams and Lipo-, Glyco-, and Lipoglycopeptides, Is Independent of the Seesaw Effect in Methicillin-Resistant Staphylococcus aureus | Front Mol Biosci. 2021 Sep 9;8:688357. doi: 10.3389/fmolb.2021.688357. eCollection 2021. | 10.3389/fmolb.2021.688357 | https://doi.org/10.3389/fmolb.2021.688357 | Medicinal Chemistry | |
| Xu | 33269585 | 2021 | Do Q | Development and Application of a Peroxyl Radical Clock Approach for Measuring Both Hydrogen-Atom Transfer and Peroxyl Radical Addition Rate Constants | J Org Chem. 2021 Jan 1;86(1):153-168. doi: 10.1021/acs.joc.0c01920. Epub 2020 Dec 3. | 10.1021/acs.joc.0c01920 | https://doi.org/10.1021/acs.joc.0c01920 | Medicinal Chemistry | |
| Xu | 37873113 | 2025 | Li A | MALDI-IM-MS Imaging of Brain Sterols and Lipids in a Mouse Model of Smith-Lemli-Opitz Syndrome | bioRxiv [Preprint]. 2025 Aug 12:2023.10.02.560415. doi: 10.1101/2023.10.02.560415. | 10.1101/2023.10.02.560415 | https://doi.org/10.1101/2023.10.02.560415 | Medicinal Chemistry | |
| Xu | 37904970 | 2023 | Miller WR | Membrane Lipids Augment Cell Envelope Stress Signaling and Resistance to Antibiotics and Antimicrobial Peptides in Enterococcus faecalis | bioRxiv [Preprint]. 2023 Oct 19:2023.10.17.562839. doi: 10.1101/2023.10.17.562839. | 10.1101/2023.10.17.562839 | https://doi.org/10.1101/2023.10.17.562839 | Medicinal Chemistry | |
| Xu | 32866650 | 2021 | Werth BJ | Dalbavancin exposure in vitro selects for dalbavancin-non-susceptible and vancomycin-intermediate strains of methicillin-resistant Staphylococcus aureus | Clin Microbiol Infect. 2021 Jun;27(6):910.e1-910.e8. doi: 10.1016/j.cmi.2020.08.025. Epub 2020 Aug 28. | 10.1016/j.cmi.2020.08.025 | https://doi.org/10.1016/j.cmi.2020.08.025 | Medicinal Chemistry | |
| Xu | 34179085 | 2021 | Shen T | Varied Contribution of Phospholipid Shedding From Membrane to Daptomycin Tolerance in Staphylococcus aureus | Front Mol Biosci. 2021 Jun 11;8:679949. doi: 10.3389/fmolb.2021.679949. eCollection 2021. | 10.3389/fmolb.2021.679949 | https://doi.org/10.3389/fmolb.2021.679949 | Medicinal Chemistry | |
| Xu | 35510938 | 2022 | Zhang R | Emergence of Dalbavancin, Vancomycin, and Daptomycin Nonsusceptible Staphylococcus aureus in a Patient Treated With Dalbavancin: Case Report and Isolate Characterization | Clin Infect Dis. 2022 Oct 29;75(9):1641-1644. doi: 10.1093/cid/ciac341. | 10.1093/cid/ciac341 | https://doi.org/10.1093/cid/ciac341 | Medicinal Chemistry | |
| Xu | 39936452 | 2025 | Werth BJ | Simulated exposures of oritavancin in in vitro pharmacodynamic models select for methicillin-resistant Staphylococcus aureus with reduced susceptibility to oritavancin but minimal cross-resistance or seesaw effect with other antimicrobials | J Antimicrob Chemother. 2025 Apr 2;80(4):1108-1115. doi: 10.1093/jac/dkaf042. | 10.1093/jac/dkaf042 | https://doi.org/10.1093/jac/dkaf042 | Medicinal Chemistry | |
| Xu | 33472002 | 2021 | Herron JM | Benzalkonium Chloride Disinfectants Induce Apoptosis, Inhibit Proliferation, and Activate the Integrated Stress Response in a 3-D in Vitro Model of Neurodevelopment | Chem Res Toxicol. 2021 May 17;34(5):1265-1274. doi: 10.1021/acs.chemrestox.0c00386. Epub 2021 Jan 20. | 10.1021/acs.chemrestox.0c00386 | https://doi.org/10.1021/acs.chemrestox.0c00386 | Medicinal Chemistry | |
| Xu | 39500386 | 2025 | Raskovic D | Growth of Staphylococcus aureus in the presence of oleic acid shifts the glycolipid fatty acid profile and increases resistance to antimicrobial peptides | Biochim Biophys Acta Biomembr. 2025 Jan;1867(1):184395. doi: 10.1016/j.bbamem.2024.184395. Epub 2024 Nov 3. | 10.1016/j.bbamem.2024.184395 | https://doi.org/10.1016/j.bbamem.2024.184395 | Medicinal Chemistry | |
| Xu | 38045361 | 2025 | Li A | Temporal transcriptomic changes during neurodevelopment in a mouse model of Smith-Lemli-Opitz syndrome | bioRxiv [Preprint]. 2025 Aug 12:2023.11.21.568116. doi: 10.1101/2023.11.21.568116. | 10.1101/2023.11.21.568116 | https://doi.org/10.1101/2023.11.21.568116 | Medicinal Chemistry | |
| Xu | 39957787 | 2025 | Elapavalore A | PubChemLite Plus Collision Cross Section (CCS) Values for Enhanced Interpretation of Nontarget Environmental Data | Environ Sci Technol Lett. 2025 Jan 24;12(2):166-174. doi: 10.1021/acs.estlett.4c01003. eCollection 2025 Feb 11. | 10.1021/acs.estlett.4c01003 | https://doi.org/10.1021/acs.estlett.4c01003 | Medicinal Chemistry | |
| Xu | 41190598 | 2025 | Kula J | Maternal and Placental Inflammation Influence Formation of Neural Tube Defects in Quaternary Ammonium Compound Exposed Mice | Birth Defects Res. 2025 Nov;117(11):e2539. doi: 10.1002/bdr2.2539. | 10.1002/bdr2.2539 | https://doi.org/10.1002/bdr2.2539 | Medicinal Chemistry | |
| Xu | 41506459 | 2026 | Li A | Temporal transcriptomic changes during neurodevelopment in a mouse model of Smith-Lemli-Opitz syndrome | J Steroid Biochem Mol Biol. 2026 Mar;257:106935. doi: 10.1016/j.jsbmb.2026.106935. Epub 2026 Jan 6. | 10.1016/j.jsbmb.2026.106935 | https://doi.org/10.1016/j.jsbmb.2026.106935 | 4/28/26 | Medicinal Chemistry |
| Xu | 38578967 | 2025 | Miller WR | Membrane Lipids Augment Cell Envelope Stress Signaling via the MadRS System to Defend Against Antimicrobial Peptides and Antibiotics in Enterococcus faecalis | J Infect Dis. 2025 Feb 20;231(2):307-317. doi: 10.1093/infdis/jiae173. | 10.1093/infdis/jiae173 | https://doi.org/10.1093/infdis/jiae173 | Medicinal Chemistry | |
| Xu | 40912167 | 2025 | Colonna MB | Expansion of genotype/phenotype correlation in an individual with compound heterozygous variants in CYP51A1 and congenital cataract | Mol Genet Metab. 2025 Sep-Oct;146(1-2):109230. doi: 10.1016/j.ymgme.2025.109230. Epub 2025 Sep 2. | 10.1016/j.ymgme.2025.109230 | https://doi.org/10.1016/j.ymgme.2025.109230 | Medicinal Chemistry |
| PI Association | PMID | Publication Year | First Author | Title | Citation | DOI | Department | ||
|---|---|---|---|---|---|---|---|---|---|
| Nath | 39837577 | 2025 | Tuttle LM | Rigorous Analysis of Multimodal HDX-MS Spectra | J Am Soc Mass Spectrom. 2025 Feb 5;36(2):416-423. doi: 10.1021/jasms.4c00471. Epub 2025 Jan 21. | 10.1021/jasms.4c00471 | https://doi.org/10.1021/jasms.4c00471 | 4/28/26 | Medicinal Chemistry |
| Nath | 42541914 | 2026 | Authement AK | Modeling cortisol and cortisone binding to corticosteroid-binding globulin and albumin based on clinical protein binding data. | Drug Metab Dispos. 2026 Aug;54(8):100362. doi: 10.1016/j.dmd.2026.100362. Epub 2026 Jul 9. | 10.1016/j.dmd.2026.100362 | https://doi.org/10.1016/j.dmd.2026.100362 | 10/14/26 | Medicinal Chemistry |
| Nath | 42039475 | 2026 | Authement AK | Kinetics of cortisol and cortisone binding to corticosteroid binding globulin and albumin in vivo. | bioRxiv [Preprint]. 2026 Apr 17:2026.04.14.718600. doi: 10.64898/2026.04.14.718600. | 10.64898/2026.04.14.718600 | https://doi.org/10.64898/2026.04.14.718600 | 6/26/26 | Medicinal Chemistry |
| Nath | 41899522 | 2026 | Mariano IP | Biophysical and Structural Characterization of Antibody-Drug Conjugates | Cancers (Basel). 2026 Mar 12;18(6):917. doi: 10.3390/cancers18060917. | 10.3390/cancers18060917 | https://doi.org/10.3390/cancers18060917 | Medicinal Chemistry | |
| Nath | 38478383 | 2024 | Wiley AM | Investigating the association between CYP2J2 inhibitors and QT prolongation: a literature review | Drug Metab Rev. 2024 Feb-May;56(2):145-163. doi: 10.1080/03602532.2024.2329928. Epub 2024 Mar 20. | 10.1080/03602532.2024.2329928 | https://doi.org/10.1080/03602532.2024.2329928 | Medicinal Chemistry | |
| Nath | 35147406 | 2022 | Baggett DW | Structure-Activity Relationships of Novel Tau Ligands: Passive Fibril Binders and Active Aggregation Inhibitors | ACS Chem Biol. 2022 Mar 18;17(3):701-708. doi: 10.1021/acschembio.2c00012. Epub 2022 Feb 11. | 10.1021/acschembio.2c00012 | https://doi.org/10.1021/acschembio.2c00012 | Medicinal Chemistry | |
| Nath | 36194135 | 2022 | Kunk C | MitoNEET’s Reactivity of Lys55 toward Pyridoxal Phosphate Demonstrates its Activity as a Transaminase Enzyme | ACS Chem Biol. 2022 Oct 21;17(10):2716-2722. doi: 10.1021/acschembio.2c00572. Epub 2022 Oct 4. | 10.1021/acschembio.2c00572 | https://doi.org/10.1021/acschembio.2c00572 | Medicinal Chemistry | |
| Nath | 38352474 | 2024 | James EI | Tryptanthrin Analogs Substoichiometrically Inhibit Seeded and Unseeded Tau4RD Aggregation | bioRxiv [Preprint]. 2024 Feb 3:2024.02.02.578649. doi: 10.1101/2024.02.02.578649. | 10.1101/2024.02.02.578649 | https://doi.org/10.1101/2024.02.02.578649 | Medicinal Chemistry | |
| Nath | 37861473 | 2023 | Larsen HA | The origins of nonideality exhibited by monoclonal antibodies and Fab fragments in human serum | Protein Sci. 2023 Dec;32(12):e4812. doi: 10.1002/pro.4812. | 10.1002/pro.4812 | https://doi.org/10.1002/pro.4812 | Medicinal Chemistry | |
| Nath | 37562955 | 2023 | Alade N | The Utility of Mixed Effects Models in the Evaluation of Complex Genomic Traits In Vitro | Drug Metab Dispos. 2023 Nov;51(11):1455-1462. doi: 10.1124/dmd.123.001260. Epub 2023 Aug 10. | 10.1124/dmd.123.001260 | https://doi.org/10.1124/dmd.123.001260 | Medicinal Chemistry | |
| Nath | 36948348 | 2023 | Redhair M | Low molecular weight ligands bind to CYP3A4 via a branched induced fit mechanism: Implications for O(2) binding | Arch Biochem Biophys. 2023 May 1;739:109582. doi: 10.1016/j.abb.2023.109582. Epub 2023 Mar 21. | 10.1016/j.abb.2023.109582 | https://doi.org/10.1016/j.abb.2023.109582 | Medicinal Chemistry | |
| Nath | 34384764 | 2021 | Larsen HA | Probing interactions of therapeutic antibodies with serum via second virial coefficient measurements | Biophys J. 2021 Sep 21;120(18):4067-4078. doi: 10.1016/j.bpj.2021.08.007. Epub 2021 Aug 10. | 10.1016/j.bpj.2021.08.007 | https://doi.org/10.1016/j.bpj.2021.08.007 | Medicinal Chemistry | |
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| Xu | 39276938 | 2024 | Hass DT | Acetyl-CoA carboxylase inhibition increases retinal pigment epithelial cell fatty acid flux and restricts apolipoprotein efflux | J Biol Chem. 2024 Oct;300(10):107772. doi: 10.1016/j.jbc.2024.107772. Epub 2024 Sep 12. | 10.1016/j.jbc.2024.107772 | https://doi.org/10.1016/j.jbc.2024.107772 | Medicinal Chemistry | |
| Xu | 38307853 | 2024 | Vieira LS | Interaction and Transport of Benzalkonium Chlorides by the Organic Cation and Multidrug and Toxin Extrusion Transporters | Drug Metab Dispos. 2024 Mar 13;52(4):312-321. doi: 10.1124/dmd.123.001625. | 10.1124/dmd.123.001625 | https://doi.org/10.1124/dmd.123.001625 | Medicinal Chemistry | |
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| Xu | 37425828 | 2023 | Pruitt EL | Elucidating the Impact of Bacterial Lipases, Human Serum Albumin, and FASII Inhibition on the Utilization of Exogenous Fatty Acids by Staphylococcus aureus | bioRxiv [Preprint]. 2023 Jun 30:2023.06.29.547085. doi: 10.1101/2023.06.29.547085. | 10.1101/2023.06.29.547085 | https://doi.org/10.1101/2023.06.29.547085 | Medicinal Chemistry | |
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| Xu | 39363503 | 2024 | Lopez VA | Oral exposure to benzalkonium chlorides in male and female mice reveals alteration of the gut microbiome and bile acid profile | Toxicol Sci. 2024 Dec 1;202(2):265-277. doi: 10.1093/toxsci/kfae116. | 10.1093/toxsci/kfae116 | https://doi.org/10.1093/toxsci/kfae116 | Medicinal Chemistry | |
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| Xu | 41366203 | 2025 | Zhao HN | A resource to empirically establish drug exposure records directly from untargeted metabolomics data | Nat Commun. 2025 Dec 9;16(1):10600. doi: 10.1038/s41467-025-65993-5. | 10.1038/s41467-025-65993-5 | https://doi.org/10.1038/s41467-025-65993-5 | Medicinal Chemistry | |
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| Xu | 35175195 | 2022 | Ting SY | Discovery of coordinately regulated pathways that provide innate protection against interbacterial antagonism | Elife. 2022 Feb 17;11:e74658. doi: 10.7554/eLife.74658. | 10.7554/eLife.74658 | https://doi.org/10.7554/eLife.74658 | Medicinal Chemistry | |
| Xu | 39192580 | 2024 | Weakly HMJ | Several common methods of making vesicles (except an emulsion method) capture intended lipid ratios | Biophys J. 2024 Oct 1;123(19):3452-3462. doi: 10.1016/j.bpj.2024.08.019. Epub 2024 Aug 26. | 10.1016/j.bpj.2024.08.019 | https://doi.org/10.1016/j.bpj.2024.08.019 | Medicinal Chemistry | |
| Xu | 33652836 | 2021 | Pfeffer BA | Transcriptomic Changes Associated with Loss of Cell Viability Induced by Oxysterol Treatment of a Retinal Photoreceptor-Derived Cell Line: An In Vitro Model of Smith-Lemli-Opitz Syndrome | Int J Mol Sci. 2021 Feb 26;22(5):2339. doi: 10.3390/ijms22052339. | 10.3390/ijms22052339 | https://doi.org/10.3390/ijms22052339 | Medicinal Chemistry | |
| Xu | 38746422 | 2024 | Raskovic D | Growth of Staphylococcus aureus in the presence of oleic acid shifts the glycolipid fatty acid profile and increases resistance to antimicrobial peptides | bioRxiv [Preprint]. 2024 May 5:2024.05.03.592415. doi: 10.1101/2024.05.03.592415. | 10.1101/2024.05.03.592415 | https://doi.org/10.1101/2024.05.03.592415 | Medicinal Chemistry | |
| Xu | 37577529 | 2023 | Daggubati V | Hedgehog target genes regulate lipid metabolism to drive basal cell carcinoma and medulloblastoma | Res Sq [Preprint]. 2023 Aug 3:rs.3.rs-3058335. doi: 10.21203/rs.3.rs-3058335/v1. | 10.21203/rs.3.rs-3058335/v1 | https://doi.org/10.21203/rs.3.rs-3058335/v1 | Medicinal Chemistry | |
| Xu | 33868951 | 2021 | Hrubec TC | Altered toxicological endpoints in humans from common quaternary ammonium compound disinfectant exposure | Toxicol Rep. 2021 Mar 9;8:646-656. doi: 10.1016/j.toxrep.2021.03.006. eCollection 2021. | 10.1016/j.toxrep.2021.03.006 | https://doi.org/10.1016/j.toxrep.2021.03.006 | Medicinal Chemistry | |
| Xu | 33476305 | 2021 | Daggubati V | Smoothened-activating lipids drive resistance to CDK4/6 inhibition in Hedgehog-associated medulloblastoma cells and preclinical models | J Clin Invest. 2021 Mar 15;131(6):e141171. doi: 10.1172/JCI141171. | 10.1172/JCI141171 | https://doi.org/10.1172/JCI141171 | Medicinal Chemistry | |
| Xu | 33057715 | 2021 | Shen T | Identification of a novel tedizolid resistance mutation in rpoB of MRSA after in vitro serial passage | J Antimicrob Chemother. 2021 Jan 19;76(2):292-296. doi: 10.1093/jac/dkaa422. | 10.1093/jac/dkaa422 | https://doi.org/10.1093/jac/dkaa422 | Medicinal Chemistry | |
| Xu | 34646861 | 2021 | Zhang R | Synergy Between Beta-Lactams and Lipo-, Glyco-, and Lipoglycopeptides, Is Independent of the Seesaw Effect in Methicillin-Resistant Staphylococcus aureus | Front Mol Biosci. 2021 Sep 9;8:688357. doi: 10.3389/fmolb.2021.688357. eCollection 2021. | 10.3389/fmolb.2021.688357 | https://doi.org/10.3389/fmolb.2021.688357 | Medicinal Chemistry | |
| Xu | 33269585 | 2021 | Do Q | Development and Application of a Peroxyl Radical Clock Approach for Measuring Both Hydrogen-Atom Transfer and Peroxyl Radical Addition Rate Constants | J Org Chem. 2021 Jan 1;86(1):153-168. doi: 10.1021/acs.joc.0c01920. Epub 2020 Dec 3. | 10.1021/acs.joc.0c01920 | https://doi.org/10.1021/acs.joc.0c01920 | Medicinal Chemistry | |
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| Xu | 37904970 | 2023 | Miller WR | Membrane Lipids Augment Cell Envelope Stress Signaling and Resistance to Antibiotics and Antimicrobial Peptides in Enterococcus faecalis | bioRxiv [Preprint]. 2023 Oct 19:2023.10.17.562839. doi: 10.1101/2023.10.17.562839. | 10.1101/2023.10.17.562839 | https://doi.org/10.1101/2023.10.17.562839 | Medicinal Chemistry | |
| Xu | 32866650 | 2021 | Werth BJ | Dalbavancin exposure in vitro selects for dalbavancin-non-susceptible and vancomycin-intermediate strains of methicillin-resistant Staphylococcus aureus | Clin Microbiol Infect. 2021 Jun;27(6):910.e1-910.e8. doi: 10.1016/j.cmi.2020.08.025. Epub 2020 Aug 28. | 10.1016/j.cmi.2020.08.025 | https://doi.org/10.1016/j.cmi.2020.08.025 | Medicinal Chemistry | |
| Xu | 34179085 | 2021 | Shen T | Varied Contribution of Phospholipid Shedding From Membrane to Daptomycin Tolerance in Staphylococcus aureus | Front Mol Biosci. 2021 Jun 11;8:679949. doi: 10.3389/fmolb.2021.679949. eCollection 2021. | 10.3389/fmolb.2021.679949 | https://doi.org/10.3389/fmolb.2021.679949 | Medicinal Chemistry | |
| Xu | 35510938 | 2022 | Zhang R | Emergence of Dalbavancin, Vancomycin, and Daptomycin Nonsusceptible Staphylococcus aureus in a Patient Treated With Dalbavancin: Case Report and Isolate Characterization | Clin Infect Dis. 2022 Oct 29;75(9):1641-1644. doi: 10.1093/cid/ciac341. | 10.1093/cid/ciac341 | https://doi.org/10.1093/cid/ciac341 | Medicinal Chemistry | |
| Xu | 39936452 | 2025 | Werth BJ | Simulated exposures of oritavancin in in vitro pharmacodynamic models select for methicillin-resistant Staphylococcus aureus with reduced susceptibility to oritavancin but minimal cross-resistance or seesaw effect with other antimicrobials | J Antimicrob Chemother. 2025 Apr 2;80(4):1108-1115. doi: 10.1093/jac/dkaf042. | 10.1093/jac/dkaf042 | https://doi.org/10.1093/jac/dkaf042 | Medicinal Chemistry | |
| Xu | 33472002 | 2021 | Herron JM | Benzalkonium Chloride Disinfectants Induce Apoptosis, Inhibit Proliferation, and Activate the Integrated Stress Response in a 3-D in Vitro Model of Neurodevelopment | Chem Res Toxicol. 2021 May 17;34(5):1265-1274. doi: 10.1021/acs.chemrestox.0c00386. Epub 2021 Jan 20. | 10.1021/acs.chemrestox.0c00386 | https://doi.org/10.1021/acs.chemrestox.0c00386 | Medicinal Chemistry | |
| Xu | 39500386 | 2025 | Raskovic D | Growth of Staphylococcus aureus in the presence of oleic acid shifts the glycolipid fatty acid profile and increases resistance to antimicrobial peptides | Biochim Biophys Acta Biomembr. 2025 Jan;1867(1):184395. doi: 10.1016/j.bbamem.2024.184395. Epub 2024 Nov 3. | 10.1016/j.bbamem.2024.184395 | https://doi.org/10.1016/j.bbamem.2024.184395 | Medicinal Chemistry | |
| Xu | 38045361 | 2025 | Li A | Temporal transcriptomic changes during neurodevelopment in a mouse model of Smith-Lemli-Opitz syndrome | bioRxiv [Preprint]. 2025 Aug 12:2023.11.21.568116. doi: 10.1101/2023.11.21.568116. | 10.1101/2023.11.21.568116 | https://doi.org/10.1101/2023.11.21.568116 | Medicinal Chemistry | |
| Xu | 39957787 | 2025 | Elapavalore A | PubChemLite Plus Collision Cross Section (CCS) Values for Enhanced Interpretation of Nontarget Environmental Data | Environ Sci Technol Lett. 2025 Jan 24;12(2):166-174. doi: 10.1021/acs.estlett.4c01003. eCollection 2025 Feb 11. | 10.1021/acs.estlett.4c01003 | https://doi.org/10.1021/acs.estlett.4c01003 | Medicinal Chemistry | |
| Xu | 41190598 | 2025 | Kula J | Maternal and Placental Inflammation Influence Formation of Neural Tube Defects in Quaternary Ammonium Compound Exposed Mice | Birth Defects Res. 2025 Nov;117(11):e2539. doi: 10.1002/bdr2.2539. | 10.1002/bdr2.2539 | https://doi.org/10.1002/bdr2.2539 | Medicinal Chemistry | |
| Xu | 41506459 | 2026 | Li A | Temporal transcriptomic changes during neurodevelopment in a mouse model of Smith-Lemli-Opitz syndrome | J Steroid Biochem Mol Biol. 2026 Mar;257:106935. doi: 10.1016/j.jsbmb.2026.106935. Epub 2026 Jan 6. | 10.1016/j.jsbmb.2026.106935 | https://doi.org/10.1016/j.jsbmb.2026.106935 | 4/28/26 | Medicinal Chemistry |
| Xu | 38578967 | 2025 | Miller WR | Membrane Lipids Augment Cell Envelope Stress Signaling via the MadRS System to Defend Against Antimicrobial Peptides and Antibiotics in Enterococcus faecalis | J Infect Dis. 2025 Feb 20;231(2):307-317. doi: 10.1093/infdis/jiae173. | 10.1093/infdis/jiae173 | https://doi.org/10.1093/infdis/jiae173 | Medicinal Chemistry | |
| Xu | 40912167 | 2025 | Colonna MB | Expansion of genotype/phenotype correlation in an individual with compound heterozygous variants in CYP51A1 and congenital cataract | Mol Genet Metab. 2025 Sep-Oct;146(1-2):109230. doi: 10.1016/j.ymgme.2025.109230. Epub 2025 Sep 2. | 10.1016/j.ymgme.2025.109230 | https://doi.org/10.1016/j.ymgme.2025.109230 | Medicinal Chemistry |
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| Nath | 42541914 | 2026 | Authement AK | Modeling cortisol and cortisone binding to corticosteroid-binding globulin and albumin based on clinical protein binding data. | Drug Metab Dispos. 2026 Aug;54(8):100362. doi: 10.1016/j.dmd.2026.100362. Epub 2026 Jul 9. | 10.1016/j.dmd.2026.100362 | https://doi.org/10.1016/j.dmd.2026.100362 | 10/14/26 | Medicinal Chemistry |
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| Nath | 35147406 | 2022 | Baggett DW | Structure-Activity Relationships of Novel Tau Ligands: Passive Fibril Binders and Active Aggregation Inhibitors | ACS Chem Biol. 2022 Mar 18;17(3):701-708. doi: 10.1021/acschembio.2c00012. Epub 2022 Feb 11. | 10.1021/acschembio.2c00012 | https://doi.org/10.1021/acschembio.2c00012 | Medicinal Chemistry | |
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| Nath | 33057715 | 2021 | Shen T | Identification of a novel tedizolid resistance mutation in rpoB of MRSA after in vitro serial passage | J Antimicrob Chemother. 2021 Jan 19;76(2):292-296. doi: 10.1093/jac/dkaa422. | 10.1093/jac/dkaa422 | https://doi.org/10.1093/jac/dkaa422 | Medicinal Chemistry | |
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| Xu | 42249845 | 2026 | Nguyen R | IMFrag: A Tool to Recognize In-Source Fragmentation in Ion Mobility-Enabled Data-Independent Acquisition Workflows | Anal Chem. 2026 Jun 23;98(24):17988-17998. doi: 10.1021/acs.analchem.6c01388. Epub 2026 Jun 6. PMCID: PMC13295093. | 10.1021/acs.analchem.6c01388 | https://doi.org/10.1021/acs.analchem.6c01388 | 10/14/26 | Medicinal Chemistry |
| Xu | 42262507 | 2026 | Nguyen R | ToxBase: A Multidimensional ToxCast Reference Database for High-Throughput Human Exposome Analysis | Environ Sci Technol. 2026 Jun 23;60(24):17314-17327. doi: 10.1021/acs.est.5c18068. Epub 2026 Jun 9. PMCID: PMC13296496. | 10.1021/acs.est.5c18068 | https://doi.org/10.1021/acs.est.5c18068 | 10/14/26 | Medicinal Chemistry |
| Xu | 42273072 | 2026 | Reimers N | Peroxidation rate constants and mechanisms of isoprenoid-derived lipids and their roles in ferroptosis | Redox Biochem Chem. 2025 Sep;13:100058. doi: 10.1016/j.rbc.2025.100058. Epub 2025 Aug 22. PMCID: PMC13249365. | 10.1016/j.rbc.2025.100058 | https://doi.org/10.1016/j.rbc.2025.100058 | 10/14/26 | Medicinal Chemistry |
| Xu | 42358553 | 2026 | Li Z | Multidisciplinary team care and outcomes in FNCLCC grade 3 soft tissue sarcoma: a propensity score-matched and weighted cohort study | Front Oncol. 2026 Jun 10;16:1827237. doi: 10.3389/fonc.2026.1827237 | 10.3389/fonc.2026.1827237 | https://doi.org/10.3389/fonc.2026.1827237 | 10/14/26 | Medicinal Chemistry |
| Xu | 42401068 | 2026 | Xu L | Dihydroberberine regulates the ferroptosis-autophagy positive feedback loop in colorectal cancer by targeting PANX2 | Phytomedicine. 2026 Sep;159:158537. doi: 10.1016/j.phymed.2026.158537. Epub 2026 Jul 1. | 10.1016/j.phymed.2026.158537 | https://doi.org/10.1016/j.phymed.2026.158537 | 10/14/26 | Medicinal Chemistry |
| Xu | 42482346 | 2026 | Yuan W | Activation of Allylic Primary Alcohols With Biaryl Oxazepine Reagent for Chiral Phosphoric Acid-Catalyzed Asymmetric SN1 Reaction | Angew Chem Int Ed Engl. 2026 Sep 21;65(39):e5149199. doi: 10.1002/anie.5149199. Epub 2026 Jul 21. | 10.1002/anie.5149199 | https://doi.org/10.1002/anie.5149199 | 10/14/26 | Medicinal Chemistry |
| Xu | 42184204 | 2026 | Brzoska MN | Benzalkonium Chloride-Induced Nephrotoxicity in 2D Cultures and a Human Kidney-on-a-Chip System. | Environ Sci Technol. 2026 Jun 9;60(22):15557-15569. doi: 10.1021/acs.est.5c15625. Epub 2026 May 25. | 10.1021/acs.est.5c15625 | https://doi.org/10.1021/acs.est.5c15625 | 6/26/26 | Medicinal Chemistry |
| Xu | 41735104 | 2026 | Xu L | Corrigendum to “Effusol ameliorates ischemic stroke by targeting NLRP3 protein to regulate NLRP3 inflammasome-mediated pyroptosis” | Phytomedicine. 2026 Mar;152:157834. doi: 10.1016/j.phymed.2026.157834. Epub 2026 Feb 3. Erratum for: Phytomedicine. 2025 Jan;136:156253. doi: 10.1016/j.phymed.2024.156253. | 10.1016/j.phymed.2026.157834 | https://doi.org/10.1016/j.phymed.2026.157834 | 4/28/26 | Medicinal Chemistry |
| Xu | 41880181 | 2026 | Adcock L | Differential and Sex-Specific Toxicity of Aspirated Quaternary Ammonium Compounds | Environ Sci Technol. 2026 Apr 7;60(13):9872-9880. doi: 10.1021/acs.est.5c13204. Epub 2026 Mar 25. | 10.1021/acs.est.5c13204 | https://doi.org/10.1021/acs.est.5c13204 | 4/28/26 | Medicinal Chemistry |
| Xu | 41822371 | 2026 | Stohs EJ | Emergence of Dalbavancin, Vancomycin, and Daptomycin Cross-resistance in MRSA During Long-term LVAD Suppression With Vancomycin Followed by Dalbavancin: Genomic Insights and Synergy With Cefadroxil | Open Forum Infect Dis. 2026 Feb 16;13(3):ofag074. doi: 10.1093/ofid/ofag074. | 10.1093/ofid/ofag074 | https://doi.org/10.1093/ofid/ofag074 | 4/28/26 | Medicinal Chemistry |
| Xu | 41820720 | 2026 | Cheng R, | Assessing the Recovery of Muscle Fatigue Using Shear Wave Elastography | Sports Med Open. 2026 Mar 12;12(1):30. doi: 10.1186/s40798-026-00991-5. | 10.1186/s40798-026-00991-5 | https://doi.org/10.1186/s40798-026-00991-5 | 4/28/26 | Medicinal Chemistry |
| Xu | 41793791 | 2026 | Xu L | KLK8 promotes cartilage degradation and pyroptosis in osteoarthritis by activating the NF-κB and NLRP3 inflammasome pathways | Tissue Cell. 2026 Feb 27;101:103427. doi: 10.1016/j.tice.2026.103427. Epub ahead of print. | 10.1016/j.tice.2026.103427 | https://doi.org/10.1016/j.tice.2026.103427 | 4/28/26 | Medicinal Chemistry |
| Xu | 40140573 | 2025 | Ha YJ | The contribution of de novo coding mutations to meningomyelocele | Nature. 2025 May;641(8062):419-426. doi: 10.1038/s41586-025-08676-x. Epub 2025 Mar 26. | 10.1038/s41586-025-08676-x | https://doi.org/10.1038/s41586-025-08676-x | Medicinal Chemistry | |
| Xu | 37157132 | 2023 | Arnold WA | Quaternary Ammonium Compounds: A Chemical Class of Emerging Concern | Environ Sci Technol. 2023 May 23;57(20):7645-7665. doi: 10.1021/acs.est.2c08244. Epub 2023 May 8. | 10.1021/acs.est.2c08244 | https://doi.org/10.1021/acs.est.2c08244 | Medicinal Chemistry | |
| Xu | 39405116 | 2024 | Nguyen AH | Molecular basis of cell membrane adaptation in daptomycin-resistant Enterococcus faecalis | JCI Insight. 2024 Nov 22;9(22):e173836. doi: 10.1172/jci.insight.173836. | 10.1172/jci.insight.173836 | https://doi.org/10.1172/jci.insight.173836 | Medicinal Chemistry | |
| Xu | 33736803 | 2021 | Ross DH | Determination of drugs and drug metabolites by ion mobility-mass spectrometry: A review | Anal Chim Acta. 2021 Apr 15;1154:338270. doi: 10.1016/j.aca.2021.338270. Epub 2021 Feb 2. | 10.1016/j.aca.2021.338270 | https://doi.org/10.1016/j.aca.2021.338270 | Medicinal Chemistry | |
| Xu | 36111785 | 2022 | Tomita H | 7-Dehydrocholesterol-derived oxysterols cause neurogenic defects in Smith-Lemli-Opitz syndrome | Elife. 2022 Sep 16;11:e67141. doi: 10.7554/eLife.67141. | 10.7554/eLife.67141 | https://doi.org/10.7554/eLife.67141 | Medicinal Chemistry | |
| Xu | 40133959 | 2025 | Li J | Radiation-induced ferroptosis via liposomal delivery of 7-Dehydrocholesterol | J Nanobiotechnology. 2025 Mar 26;23(1):249. doi: 10.1186/s12951-025-03303-3. | 10.1186/s12951-025-03303-3 | https://doi.org/10.1186/s12951-025-03303-3 | Medicinal Chemistry | |
| Xu | 38077958 | 2023 | Elias ER | Cholic acid increases plasma cholesterol in Smith-Lemli-Opitz syndrome: A pilot study | Mol Genet Metab Rep. 2023 Nov 28;38:101030. doi: 10.1016/j.ymgmr.2023.101030. eCollection 2024 Mar. | 10.1016/j.ymgmr.2023.101030 | https://doi.org/10.1016/j.ymgmr.2023.101030 | Medicinal Chemistry | |
| Xu | 33284321 | 2021 | Findakly S | Sterol and oxysterol synthases near the ciliary base activate the Hedgehog pathway | J Cell Biol. 2021 Jan 4;220(1):e202002026. doi: 10.1083/jcb.202002026. | 10.1083/jcb.202002026 | https://doi.org/10.1083/jcb.202002026 | Medicinal Chemistry | |
| Xu | 35548857 | 2022 | Ross DH | High-Throughput Measurement and Machine Learning-Based Prediction of Collision Cross Sections for Drugs and Drug Metabolites | J Am Soc Mass Spectrom. 2022 Jun 1;33(6):1061-1072. doi: 10.1021/jasms.2c00111. Epub 2022 May 11. | 10.1021/jasms.2c00111 | https://doi.org/10.1021/jasms.2c00111 | Medicinal Chemistry | |
| Xu | 38322411 | 2023 | Do Q | How do different lipid peroxidation mechanisms contribute to ferroptosis? | Cell Rep Phys Sci. 2023 Dec 20;4(12):101683. doi: 10.1016/j.xcrp.2023.101683. Epub 2023 Nov 17. | 10.1016/j.xcrp.2023.101683 | https://doi.org/10.1016/j.xcrp.2023.101683 | Medicinal Chemistry | |
| Xu | 39276938 | 2024 | Hass DT | Acetyl-CoA carboxylase inhibition increases retinal pigment epithelial cell fatty acid flux and restricts apolipoprotein efflux | J Biol Chem. 2024 Oct;300(10):107772. doi: 10.1016/j.jbc.2024.107772. Epub 2024 Sep 12. | 10.1016/j.jbc.2024.107772 | https://doi.org/10.1016/j.jbc.2024.107772 | Medicinal Chemistry | |
| Xu | 38307853 | 2024 | Vieira LS | Interaction and Transport of Benzalkonium Chlorides by the Organic Cation and Multidrug and Toxin Extrusion Transporters | Drug Metab Dispos. 2024 Mar 13;52(4):312-321. doi: 10.1124/dmd.123.001625. | 10.1124/dmd.123.001625 | https://doi.org/10.1124/dmd.123.001625 | Medicinal Chemistry | |
| Xu | 37124288 | 2023 | Do Q | Differential Contributions of Distinct Free Radical Peroxidation Mechanisms to the Induction of Ferroptosis | JACS Au. 2023 Mar 4;3(4):1100-1117. doi: 10.1021/jacsau.2c00681. eCollection 2023 Apr 24. | 10.1021/jacsau.2c00681 | https://doi.org/10.1021/jacsau.2c00681 | Medicinal Chemistry | |
| Xu | 37425828 | 2023 | Pruitt EL | Elucidating the Impact of Bacterial Lipases, Human Serum Albumin, and FASII Inhibition on the Utilization of Exogenous Fatty Acids by Staphylococcus aureus | bioRxiv [Preprint]. 2023 Jun 30:2023.06.29.547085. doi: 10.1101/2023.06.29.547085. | 10.1101/2023.06.29.547085 | https://doi.org/10.1101/2023.06.29.547085 | Medicinal Chemistry | |
| Xu | 35504891 | 2022 | Lo M | CNPY4 inhibits the Hedgehog pathway by modulating membrane sterol lipids | Nat Commun. 2022 May 3;13(1):2407. doi: 10.1038/s41467-022-30186-x. | 10.1038/s41467-022-30186-x | https://doi.org/10.1038/s41467-022-30186-x | Medicinal Chemistry | |
| Xu | 38534032 | 2024 | Nguyen R | Development and Application of a Multidimensional Database for the Detection of Quaternary Ammonium Compounds and Their Phase I Hepatic Metabolites in Humans | Environ Sci Technol. 2024 Apr 9;58(14):6236-6249. doi: 10.1021/acs.est.3c10845. Epub 2024 Mar 27. | 10.1021/acs.est.3c10845 | https://doi.org/10.1021/acs.est.3c10845 | Medicinal Chemistry | |
| Xu | 37523294 | 2023 | Reimers N | Tracking the Metabolic Fate of Exogenous Arachidonic Acid in Ferroptosis Using Dual-Isotope Labeling Lipidomics | J Am Soc Mass Spectrom. 2023 Sep 6;34(9):2016-2024. doi: 10.1021/jasms.3c00181. Epub 2023 Jul 31. | 10.1021/jasms.3c00181 | https://doi.org/10.1021/jasms.3c00181 | Medicinal Chemistry | |
| Xu | 37535099 | 2023 | Zhang R | High-throughput analysis of lipidomic phenotypes of methicillin-resistant Staphylococcus aureus by coupling in situ 96-well cultivation and HILIC-ion mobility-mass spectrometry | Anal Bioanal Chem. 2023 Oct;415(25):6191-6199. doi: 10.1007/s00216-023-04890-6. Epub 2023 Aug 3. | 10.1007/s00216-023-04890-6 | https://doi.org/10.1007/s00216-023-04890-6 | Medicinal Chemistry | |
| Xu | 35293916 | 2022 | Li A | Temporal changes in the brain lipidome during neurodevelopment of Smith-Lemli-Opitz syndrome mice | Analyst. 2022 Apr 11;147(8):1611-1621. doi: 10.1039/d2an00137c. | 10.1039/d2an00137c | https://doi.org/10.1039/d2an00137c | Medicinal Chemistry | |
| Xu | 39363503 | 2024 | Lopez VA | Oral exposure to benzalkonium chlorides in male and female mice reveals alteration of the gut microbiome and bile acid profile | Toxicol Sci. 2024 Dec 1;202(2):265-277. doi: 10.1093/toxsci/kfae116. | 10.1093/toxsci/kfae116 | https://doi.org/10.1093/toxsci/kfae116 | Medicinal Chemistry | |
| Xu | 41388019 | 2025 | Chac D | Nat Commun. 2025 Dec 12. doi: 10.1038/s41467-025-67388-y. Online ahead of print. | 10.1038/s41467-025-67388-y | https://doi.org/10.1038/s41467-025-67388-y | Medicinal Chemistry | ||
| Xu | 38014966 | 2023 | Pruitt EL | Â 42736259Â | mSphere. 2023 Dec 20;8(6):e0036823. doi: 10.1128/msphere.00368-23. Epub 2023 Nov 28. | 10.1128/msphere.00368-23 | https://doi.org/10.1128/msphere.00368-23 | Medicinal Chemistry | |
| Xu | 41366203 | 2025 | Zhao HN | A resource to empirically establish drug exposure records directly from untargeted metabolomics data | Nat Commun. 2025 Dec 9;16(1):10600. doi: 10.1038/s41467-025-65993-5. | 10.1038/s41467-025-65993-5 | https://doi.org/10.1038/s41467-025-65993-5 | Medicinal Chemistry | |
| Xu | 39416075 | 2024 | Zhao HN | Empirically establishing drug exposure records directly from untargeted metabolomics data | bioRxiv [Preprint]. 2024 Oct 26:2024.10.07.617109. doi: 10.1101/2024.10.07.617109. | 10.1101/2024.10.07.617109 | https://doi.org/10.1101/2024.10.07.617109 | Medicinal Chemistry | |
| Xu | 35175195 | 2022 | Ting SY | Discovery of coordinately regulated pathways that provide innate protection against interbacterial antagonism | Elife. 2022 Feb 17;11:e74658. doi: 10.7554/eLife.74658. | 10.7554/eLife.74658 | https://doi.org/10.7554/eLife.74658 | Medicinal Chemistry | |
| Xu | 39192580 | 2024 | Weakly HMJ | Several common methods of making vesicles (except an emulsion method) capture intended lipid ratios | Biophys J. 2024 Oct 1;123(19):3452-3462. doi: 10.1016/j.bpj.2024.08.019. Epub 2024 Aug 26. | 10.1016/j.bpj.2024.08.019 | https://doi.org/10.1016/j.bpj.2024.08.019 | Medicinal Chemistry | |
| Xu | 33652836 | 2021 | Pfeffer BA | Transcriptomic Changes Associated with Loss of Cell Viability Induced by Oxysterol Treatment of a Retinal Photoreceptor-Derived Cell Line: An In Vitro Model of Smith-Lemli-Opitz Syndrome | Int J Mol Sci. 2021 Feb 26;22(5):2339. doi: 10.3390/ijms22052339. | 10.3390/ijms22052339 | https://doi.org/10.3390/ijms22052339 | Medicinal Chemistry | |
| Xu | 38746422 | 2024 | Raskovic D | Growth of Staphylococcus aureus in the presence of oleic acid shifts the glycolipid fatty acid profile and increases resistance to antimicrobial peptides | bioRxiv [Preprint]. 2024 May 5:2024.05.03.592415. doi: 10.1101/2024.05.03.592415. | 10.1101/2024.05.03.592415 | https://doi.org/10.1101/2024.05.03.592415 | Medicinal Chemistry | |
| Xu | 37577529 | 2023 | Daggubati V | Hedgehog target genes regulate lipid metabolism to drive basal cell carcinoma and medulloblastoma | Res Sq [Preprint]. 2023 Aug 3:rs.3.rs-3058335. doi: 10.21203/rs.3.rs-3058335/v1. | 10.21203/rs.3.rs-3058335/v1 | https://doi.org/10.21203/rs.3.rs-3058335/v1 | Medicinal Chemistry | |
| Xu | 33868951 | 2021 | Hrubec TC | Altered toxicological endpoints in humans from common quaternary ammonium compound disinfectant exposure | Toxicol Rep. 2021 Mar 9;8:646-656. doi: 10.1016/j.toxrep.2021.03.006. eCollection 2021. | 10.1016/j.toxrep.2021.03.006 | https://doi.org/10.1016/j.toxrep.2021.03.006 | Medicinal Chemistry | |
| Xu | 33476305 | 2021 | Daggubati V | Smoothened-activating lipids drive resistance to CDK4/6 inhibition in Hedgehog-associated medulloblastoma cells and preclinical models | J Clin Invest. 2021 Mar 15;131(6):e141171. doi: 10.1172/JCI141171. | 10.1172/JCI141171 | https://doi.org/10.1172/JCI141171 | Medicinal Chemistry | |
| Xu | 33057715 | 2021 | Shen T | Identification of a novel tedizolid resistance mutation in rpoB of MRSA after in vitro serial passage | J Antimicrob Chemother. 2021 Jan 19;76(2):292-296. doi: 10.1093/jac/dkaa422. | 10.1093/jac/dkaa422 | https://doi.org/10.1093/jac/dkaa422 | Medicinal Chemistry | |
| Xu | 34646861 | 2021 | Zhang R | Synergy Between Beta-Lactams and Lipo-, Glyco-, and Lipoglycopeptides, Is Independent of the Seesaw Effect in Methicillin-Resistant Staphylococcus aureus | Front Mol Biosci. 2021 Sep 9;8:688357. doi: 10.3389/fmolb.2021.688357. eCollection 2021. | 10.3389/fmolb.2021.688357 | https://doi.org/10.3389/fmolb.2021.688357 | Medicinal Chemistry | |
| Xu | 33269585 | 2021 | Do Q | Development and Application of a Peroxyl Radical Clock Approach for Measuring Both Hydrogen-Atom Transfer and Peroxyl Radical Addition Rate Constants | J Org Chem. 2021 Jan 1;86(1):153-168. doi: 10.1021/acs.joc.0c01920. Epub 2020 Dec 3. | 10.1021/acs.joc.0c01920 | https://doi.org/10.1021/acs.joc.0c01920 | Medicinal Chemistry | |
| Xu | 37873113 | 2025 | Li A | MALDI-IM-MS Imaging of Brain Sterols and Lipids in a Mouse Model of Smith-Lemli-Opitz Syndrome | bioRxiv [Preprint]. 2025 Aug 12:2023.10.02.560415. doi: 10.1101/2023.10.02.560415. | 10.1101/2023.10.02.560415 | https://doi.org/10.1101/2023.10.02.560415 | Medicinal Chemistry | |
| Xu | 37904970 | 2023 | Miller WR | Membrane Lipids Augment Cell Envelope Stress Signaling and Resistance to Antibiotics and Antimicrobial Peptides in Enterococcus faecalis | bioRxiv [Preprint]. 2023 Oct 19:2023.10.17.562839. doi: 10.1101/2023.10.17.562839. | 10.1101/2023.10.17.562839 | https://doi.org/10.1101/2023.10.17.562839 | Medicinal Chemistry | |
| Xu | 32866650 | 2021 | Werth BJ | Dalbavancin exposure in vitro selects for dalbavancin-non-susceptible and vancomycin-intermediate strains of methicillin-resistant Staphylococcus aureus | Clin Microbiol Infect. 2021 Jun;27(6):910.e1-910.e8. doi: 10.1016/j.cmi.2020.08.025. Epub 2020 Aug 28. | 10.1016/j.cmi.2020.08.025 | https://doi.org/10.1016/j.cmi.2020.08.025 | Medicinal Chemistry | |
| Xu | 34179085 | 2021 | Shen T | Varied Contribution of Phospholipid Shedding From Membrane to Daptomycin Tolerance in Staphylococcus aureus | Front Mol Biosci. 2021 Jun 11;8:679949. doi: 10.3389/fmolb.2021.679949. eCollection 2021. | 10.3389/fmolb.2021.679949 | https://doi.org/10.3389/fmolb.2021.679949 | Medicinal Chemistry | |
| Xu | 35510938 | 2022 | Zhang R | Emergence of Dalbavancin, Vancomycin, and Daptomycin Nonsusceptible Staphylococcus aureus in a Patient Treated With Dalbavancin: Case Report and Isolate Characterization | Clin Infect Dis. 2022 Oct 29;75(9):1641-1644. doi: 10.1093/cid/ciac341. | 10.1093/cid/ciac341 | https://doi.org/10.1093/cid/ciac341 | Medicinal Chemistry | |
| Xu | 39936452 | 2025 | Werth BJ | Simulated exposures of oritavancin in in vitro pharmacodynamic models select for methicillin-resistant Staphylococcus aureus with reduced susceptibility to oritavancin but minimal cross-resistance or seesaw effect with other antimicrobials | J Antimicrob Chemother. 2025 Apr 2;80(4):1108-1115. doi: 10.1093/jac/dkaf042. | 10.1093/jac/dkaf042 | https://doi.org/10.1093/jac/dkaf042 | Medicinal Chemistry | |
| Xu | 33472002 | 2021 | Herron JM | Benzalkonium Chloride Disinfectants Induce Apoptosis, Inhibit Proliferation, and Activate the Integrated Stress Response in a 3-D in Vitro Model of Neurodevelopment | Chem Res Toxicol. 2021 May 17;34(5):1265-1274. doi: 10.1021/acs.chemrestox.0c00386. Epub 2021 Jan 20. | 10.1021/acs.chemrestox.0c00386 | https://doi.org/10.1021/acs.chemrestox.0c00386 | Medicinal Chemistry | |
| Xu | 39500386 | 2025 | Raskovic D | Growth of Staphylococcus aureus in the presence of oleic acid shifts the glycolipid fatty acid profile and increases resistance to antimicrobial peptides | Biochim Biophys Acta Biomembr. 2025 Jan;1867(1):184395. doi: 10.1016/j.bbamem.2024.184395. Epub 2024 Nov 3. | 10.1016/j.bbamem.2024.184395 | https://doi.org/10.1016/j.bbamem.2024.184395 | Medicinal Chemistry | |
| Xu | 38045361 | 2025 | Li A | Temporal transcriptomic changes during neurodevelopment in a mouse model of Smith-Lemli-Opitz syndrome | bioRxiv [Preprint]. 2025 Aug 12:2023.11.21.568116. doi: 10.1101/2023.11.21.568116. | 10.1101/2023.11.21.568116 | https://doi.org/10.1101/2023.11.21.568116 | Medicinal Chemistry | |
| Xu | 39957787 | 2025 | Elapavalore A | PubChemLite Plus Collision Cross Section (CCS) Values for Enhanced Interpretation of Nontarget Environmental Data | Environ Sci Technol Lett. 2025 Jan 24;12(2):166-174. doi: 10.1021/acs.estlett.4c01003. eCollection 2025 Feb 11. | 10.1021/acs.estlett.4c01003 | https://doi.org/10.1021/acs.estlett.4c01003 | Medicinal Chemistry | |
| Xu | 41190598 | 2025 | Kula J | Maternal and Placental Inflammation Influence Formation of Neural Tube Defects in Quaternary Ammonium Compound Exposed Mice | Birth Defects Res. 2025 Nov;117(11):e2539. doi: 10.1002/bdr2.2539. | 10.1002/bdr2.2539 | https://doi.org/10.1002/bdr2.2539 | Medicinal Chemistry | |
| Xu | 41506459 | 2026 | Li A | Temporal transcriptomic changes during neurodevelopment in a mouse model of Smith-Lemli-Opitz syndrome | J Steroid Biochem Mol Biol. 2026 Mar;257:106935. doi: 10.1016/j.jsbmb.2026.106935. Epub 2026 Jan 6. | 10.1016/j.jsbmb.2026.106935 | https://doi.org/10.1016/j.jsbmb.2026.106935 | 4/28/26 | Medicinal Chemistry |
| Xu | 38578967 | 2025 | Miller WR | Membrane Lipids Augment Cell Envelope Stress Signaling via the MadRS System to Defend Against Antimicrobial Peptides and Antibiotics in Enterococcus faecalis | J Infect Dis. 2025 Feb 20;231(2):307-317. doi: 10.1093/infdis/jiae173. | 10.1093/infdis/jiae173 | https://doi.org/10.1093/infdis/jiae173 | Medicinal Chemistry | |
| Xu | 40912167 | 2025 | Colonna MB | Expansion of genotype/phenotype correlation in an individual with compound heterozygous variants in CYP51A1 and congenital cataract | Mol Genet Metab. 2025 Sep-Oct;146(1-2):109230. doi: 10.1016/j.ymgme.2025.109230. Epub 2025 Sep 2. | 10.1016/j.ymgme.2025.109230 | https://doi.org/10.1016/j.ymgme.2025.109230 | Medicinal Chemistry |
| PI Association | PMID | Publication Year | First Author | Title | Citation | DOI | Department | ||
|---|---|---|---|---|---|---|---|---|---|
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| Rettie | 40932355 | 2025 | Fiume MM | Re-Review Summary of PEG Stearates as Used in Cosmetics | Int J Toxicol. 2025 Oct;44(3_suppl):100S-116S. doi: 10.1177/10915818251359230. Epub 2025 Sep 11. | 10.1177/10915818251359230 | https://doi.org/10.1177/10915818251359230 | Medicinal Chemistry | |
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| Xu | 41822371 | 2026 | Stohs EJ | Emergence of Dalbavancin, Vancomycin, and Daptomycin Cross-resistance in MRSA During Long-term LVAD Suppression With Vancomycin Followed by Dalbavancin: Genomic Insights and Synergy With Cefadroxil | Open Forum Infect Dis. 2026 Feb 16;13(3):ofag074. doi: 10.1093/ofid/ofag074. | 10.1093/ofid/ofag074 | https://doi.org/10.1093/ofid/ofag074 | 4/28/26 | Medicinal Chemistry |
| Xu | 41820720 | 2026 | Cheng R, | Assessing the Recovery of Muscle Fatigue Using Shear Wave Elastography | Sports Med Open. 2026 Mar 12;12(1):30. doi: 10.1186/s40798-026-00991-5. | 10.1186/s40798-026-00991-5 | https://doi.org/10.1186/s40798-026-00991-5 | 4/28/26 | Medicinal Chemistry |
| Xu | 41793791 | 2026 | Xu L | KLK8 promotes cartilage degradation and pyroptosis in osteoarthritis by activating the NF-κB and NLRP3 inflammasome pathways | Tissue Cell. 2026 Feb 27;101:103427. doi: 10.1016/j.tice.2026.103427. Epub ahead of print. | 10.1016/j.tice.2026.103427 | https://doi.org/10.1016/j.tice.2026.103427 | 4/28/26 | Medicinal Chemistry |
| Xu | 40140573 | 2025 | Ha YJ | The contribution of de novo coding mutations to meningomyelocele | Nature. 2025 May;641(8062):419-426. doi: 10.1038/s41586-025-08676-x. Epub 2025 Mar 26. | 10.1038/s41586-025-08676-x | https://doi.org/10.1038/s41586-025-08676-x | Medicinal Chemistry | |
| Xu | 37157132 | 2023 | Arnold WA | Quaternary Ammonium Compounds: A Chemical Class of Emerging Concern | Environ Sci Technol. 2023 May 23;57(20):7645-7665. doi: 10.1021/acs.est.2c08244. Epub 2023 May 8. | 10.1021/acs.est.2c08244 | https://doi.org/10.1021/acs.est.2c08244 | Medicinal Chemistry | |
| Xu | 39405116 | 2024 | Nguyen AH | Molecular basis of cell membrane adaptation in daptomycin-resistant Enterococcus faecalis | JCI Insight. 2024 Nov 22;9(22):e173836. doi: 10.1172/jci.insight.173836. | 10.1172/jci.insight.173836 | https://doi.org/10.1172/jci.insight.173836 | Medicinal Chemistry | |
| Xu | 33736803 | 2021 | Ross DH | Determination of drugs and drug metabolites by ion mobility-mass spectrometry: A review | Anal Chim Acta. 2021 Apr 15;1154:338270. doi: 10.1016/j.aca.2021.338270. Epub 2021 Feb 2. | 10.1016/j.aca.2021.338270 | https://doi.org/10.1016/j.aca.2021.338270 | Medicinal Chemistry | |
| Xu | 36111785 | 2022 | Tomita H | 7-Dehydrocholesterol-derived oxysterols cause neurogenic defects in Smith-Lemli-Opitz syndrome | Elife. 2022 Sep 16;11:e67141. doi: 10.7554/eLife.67141. | 10.7554/eLife.67141 | https://doi.org/10.7554/eLife.67141 | Medicinal Chemistry | |
| Xu | 40133959 | 2025 | Li J | Radiation-induced ferroptosis via liposomal delivery of 7-Dehydrocholesterol | J Nanobiotechnology. 2025 Mar 26;23(1):249. doi: 10.1186/s12951-025-03303-3. | 10.1186/s12951-025-03303-3 | https://doi.org/10.1186/s12951-025-03303-3 | Medicinal Chemistry | |
| Xu | 38077958 | 2023 | Elias ER | Cholic acid increases plasma cholesterol in Smith-Lemli-Opitz syndrome: A pilot study | Mol Genet Metab Rep. 2023 Nov 28;38:101030. doi: 10.1016/j.ymgmr.2023.101030. eCollection 2024 Mar. | 10.1016/j.ymgmr.2023.101030 | https://doi.org/10.1016/j.ymgmr.2023.101030 | Medicinal Chemistry | |
| Xu | 33284321 | 2021 | Findakly S | Sterol and oxysterol synthases near the ciliary base activate the Hedgehog pathway | J Cell Biol. 2021 Jan 4;220(1):e202002026. doi: 10.1083/jcb.202002026. | 10.1083/jcb.202002026 | https://doi.org/10.1083/jcb.202002026 | Medicinal Chemistry | |
| Xu | 35548857 | 2022 | Ross DH | High-Throughput Measurement and Machine Learning-Based Prediction of Collision Cross Sections for Drugs and Drug Metabolites | J Am Soc Mass Spectrom. 2022 Jun 1;33(6):1061-1072. doi: 10.1021/jasms.2c00111. Epub 2022 May 11. | 10.1021/jasms.2c00111 | https://doi.org/10.1021/jasms.2c00111 | Medicinal Chemistry | |
| Xu | 38322411 | 2023 | Do Q | How do different lipid peroxidation mechanisms contribute to ferroptosis? | Cell Rep Phys Sci. 2023 Dec 20;4(12):101683. doi: 10.1016/j.xcrp.2023.101683. Epub 2023 Nov 17. | 10.1016/j.xcrp.2023.101683 | https://doi.org/10.1016/j.xcrp.2023.101683 | Medicinal Chemistry | |
| Xu | 39276938 | 2024 | Hass DT | Acetyl-CoA carboxylase inhibition increases retinal pigment epithelial cell fatty acid flux and restricts apolipoprotein efflux | J Biol Chem. 2024 Oct;300(10):107772. doi: 10.1016/j.jbc.2024.107772. Epub 2024 Sep 12. | 10.1016/j.jbc.2024.107772 | https://doi.org/10.1016/j.jbc.2024.107772 | Medicinal Chemistry | |
| Xu | 38307853 | 2024 | Vieira LS | Interaction and Transport of Benzalkonium Chlorides by the Organic Cation and Multidrug and Toxin Extrusion Transporters | Drug Metab Dispos. 2024 Mar 13;52(4):312-321. doi: 10.1124/dmd.123.001625. | 10.1124/dmd.123.001625 | https://doi.org/10.1124/dmd.123.001625 | Medicinal Chemistry | |
| Xu | 37124288 | 2023 | Do Q | Differential Contributions of Distinct Free Radical Peroxidation Mechanisms to the Induction of Ferroptosis | JACS Au. 2023 Mar 4;3(4):1100-1117. doi: 10.1021/jacsau.2c00681. eCollection 2023 Apr 24. | 10.1021/jacsau.2c00681 | https://doi.org/10.1021/jacsau.2c00681 | Medicinal Chemistry | |
| Xu | 37425828 | 2023 | Pruitt EL | Elucidating the Impact of Bacterial Lipases, Human Serum Albumin, and FASII Inhibition on the Utilization of Exogenous Fatty Acids by Staphylococcus aureus | bioRxiv [Preprint]. 2023 Jun 30:2023.06.29.547085. doi: 10.1101/2023.06.29.547085. | 10.1101/2023.06.29.547085 | https://doi.org/10.1101/2023.06.29.547085 | Medicinal Chemistry | |
| Xu | 35504891 | 2022 | Lo M | CNPY4 inhibits the Hedgehog pathway by modulating membrane sterol lipids | Nat Commun. 2022 May 3;13(1):2407. doi: 10.1038/s41467-022-30186-x. | 10.1038/s41467-022-30186-x | https://doi.org/10.1038/s41467-022-30186-x | Medicinal Chemistry | |
| Xu | 38534032 | 2024 | Nguyen R | Development and Application of a Multidimensional Database for the Detection of Quaternary Ammonium Compounds and Their Phase I Hepatic Metabolites in Humans | Environ Sci Technol. 2024 Apr 9;58(14):6236-6249. doi: 10.1021/acs.est.3c10845. Epub 2024 Mar 27. | 10.1021/acs.est.3c10845 | https://doi.org/10.1021/acs.est.3c10845 | Medicinal Chemistry | |
| Xu | 37523294 | 2023 | Reimers N | Tracking the Metabolic Fate of Exogenous Arachidonic Acid in Ferroptosis Using Dual-Isotope Labeling Lipidomics | J Am Soc Mass Spectrom. 2023 Sep 6;34(9):2016-2024. doi: 10.1021/jasms.3c00181. Epub 2023 Jul 31. | 10.1021/jasms.3c00181 | https://doi.org/10.1021/jasms.3c00181 | Medicinal Chemistry | |
| Xu | 37535099 | 2023 | Zhang R | High-throughput analysis of lipidomic phenotypes of methicillin-resistant Staphylococcus aureus by coupling in situ 96-well cultivation and HILIC-ion mobility-mass spectrometry | Anal Bioanal Chem. 2023 Oct;415(25):6191-6199. doi: 10.1007/s00216-023-04890-6. Epub 2023 Aug 3. | 10.1007/s00216-023-04890-6 | https://doi.org/10.1007/s00216-023-04890-6 | Medicinal Chemistry | |
| Xu | 35293916 | 2022 | Li A | Temporal changes in the brain lipidome during neurodevelopment of Smith-Lemli-Opitz syndrome mice | Analyst. 2022 Apr 11;147(8):1611-1621. doi: 10.1039/d2an00137c. | 10.1039/d2an00137c | https://doi.org/10.1039/d2an00137c | Medicinal Chemistry | |
| Xu | 39363503 | 2024 | Lopez VA | Oral exposure to benzalkonium chlorides in male and female mice reveals alteration of the gut microbiome and bile acid profile | Toxicol Sci. 2024 Dec 1;202(2):265-277. doi: 10.1093/toxsci/kfae116. | 10.1093/toxsci/kfae116 | https://doi.org/10.1093/toxsci/kfae116 | Medicinal Chemistry | |
| Xu | 41388019 | 2025 | Chac D | Nat Commun. 2025 Dec 12. doi: 10.1038/s41467-025-67388-y. Online ahead of print. | 10.1038/s41467-025-67388-y | https://doi.org/10.1038/s41467-025-67388-y | Medicinal Chemistry | ||
| Xu | 38014966 | 2023 | Pruitt EL | Â 42736259Â | mSphere. 2023 Dec 20;8(6):e0036823. doi: 10.1128/msphere.00368-23. Epub 2023 Nov 28. | 10.1128/msphere.00368-23 | https://doi.org/10.1128/msphere.00368-23 | Medicinal Chemistry | |
| Xu | 41366203 | 2025 | Zhao HN | A resource to empirically establish drug exposure records directly from untargeted metabolomics data | Nat Commun. 2025 Dec 9;16(1):10600. doi: 10.1038/s41467-025-65993-5. | 10.1038/s41467-025-65993-5 | https://doi.org/10.1038/s41467-025-65993-5 | Medicinal Chemistry | |
| Xu | 39416075 | 2024 | Zhao HN | Empirically establishing drug exposure records directly from untargeted metabolomics data | bioRxiv [Preprint]. 2024 Oct 26:2024.10.07.617109. doi: 10.1101/2024.10.07.617109. | 10.1101/2024.10.07.617109 | https://doi.org/10.1101/2024.10.07.617109 | Medicinal Chemistry | |
| Xu | 35175195 | 2022 | Ting SY | Discovery of coordinately regulated pathways that provide innate protection against interbacterial antagonism | Elife. 2022 Feb 17;11:e74658. doi: 10.7554/eLife.74658. | 10.7554/eLife.74658 | https://doi.org/10.7554/eLife.74658 | Medicinal Chemistry | |
| Xu | 39192580 | 2024 | Weakly HMJ | Several common methods of making vesicles (except an emulsion method) capture intended lipid ratios | Biophys J. 2024 Oct 1;123(19):3452-3462. doi: 10.1016/j.bpj.2024.08.019. Epub 2024 Aug 26. | 10.1016/j.bpj.2024.08.019 | https://doi.org/10.1016/j.bpj.2024.08.019 | Medicinal Chemistry | |
| Xu | 33652836 | 2021 | Pfeffer BA | Transcriptomic Changes Associated with Loss of Cell Viability Induced by Oxysterol Treatment of a Retinal Photoreceptor-Derived Cell Line: An In Vitro Model of Smith-Lemli-Opitz Syndrome | Int J Mol Sci. 2021 Feb 26;22(5):2339. doi: 10.3390/ijms22052339. | 10.3390/ijms22052339 | https://doi.org/10.3390/ijms22052339 | Medicinal Chemistry | |
| Xu | 38746422 | 2024 | Raskovic D | Growth of Staphylococcus aureus in the presence of oleic acid shifts the glycolipid fatty acid profile and increases resistance to antimicrobial peptides | bioRxiv [Preprint]. 2024 May 5:2024.05.03.592415. doi: 10.1101/2024.05.03.592415. | 10.1101/2024.05.03.592415 | https://doi.org/10.1101/2024.05.03.592415 | Medicinal Chemistry | |
| Xu | 37577529 | 2023 | Daggubati V | Hedgehog target genes regulate lipid metabolism to drive basal cell carcinoma and medulloblastoma | Res Sq [Preprint]. 2023 Aug 3:rs.3.rs-3058335. doi: 10.21203/rs.3.rs-3058335/v1. | 10.21203/rs.3.rs-3058335/v1 | https://doi.org/10.21203/rs.3.rs-3058335/v1 | Medicinal Chemistry | |
| Xu | 33868951 | 2021 | Hrubec TC | Altered toxicological endpoints in humans from common quaternary ammonium compound disinfectant exposure | Toxicol Rep. 2021 Mar 9;8:646-656. doi: 10.1016/j.toxrep.2021.03.006. eCollection 2021. | 10.1016/j.toxrep.2021.03.006 | https://doi.org/10.1016/j.toxrep.2021.03.006 | Medicinal Chemistry | |
| Xu | 33476305 | 2021 | Daggubati V | Smoothened-activating lipids drive resistance to CDK4/6 inhibition in Hedgehog-associated medulloblastoma cells and preclinical models | J Clin Invest. 2021 Mar 15;131(6):e141171. doi: 10.1172/JCI141171. | 10.1172/JCI141171 | https://doi.org/10.1172/JCI141171 | Medicinal Chemistry | |
| Xu | 33057715 | 2021 | Shen T | Identification of a novel tedizolid resistance mutation in rpoB of MRSA after in vitro serial passage | J Antimicrob Chemother. 2021 Jan 19;76(2):292-296. doi: 10.1093/jac/dkaa422. | 10.1093/jac/dkaa422 | https://doi.org/10.1093/jac/dkaa422 | Medicinal Chemistry | |
| Xu | 34646861 | 2021 | Zhang R | Synergy Between Beta-Lactams and Lipo-, Glyco-, and Lipoglycopeptides, Is Independent of the Seesaw Effect in Methicillin-Resistant Staphylococcus aureus | Front Mol Biosci. 2021 Sep 9;8:688357. doi: 10.3389/fmolb.2021.688357. eCollection 2021. | 10.3389/fmolb.2021.688357 | https://doi.org/10.3389/fmolb.2021.688357 | Medicinal Chemistry | |
| Xu | 33269585 | 2021 | Do Q | Development and Application of a Peroxyl Radical Clock Approach for Measuring Both Hydrogen-Atom Transfer and Peroxyl Radical Addition Rate Constants | J Org Chem. 2021 Jan 1;86(1):153-168. doi: 10.1021/acs.joc.0c01920. Epub 2020 Dec 3. | 10.1021/acs.joc.0c01920 | https://doi.org/10.1021/acs.joc.0c01920 | Medicinal Chemistry | |
| Xu | 37873113 | 2025 | Li A | MALDI-IM-MS Imaging of Brain Sterols and Lipids in a Mouse Model of Smith-Lemli-Opitz Syndrome | bioRxiv [Preprint]. 2025 Aug 12:2023.10.02.560415. doi: 10.1101/2023.10.02.560415. | 10.1101/2023.10.02.560415 | https://doi.org/10.1101/2023.10.02.560415 | Medicinal Chemistry | |
| Xu | 37904970 | 2023 | Miller WR | Membrane Lipids Augment Cell Envelope Stress Signaling and Resistance to Antibiotics and Antimicrobial Peptides in Enterococcus faecalis | bioRxiv [Preprint]. 2023 Oct 19:2023.10.17.562839. doi: 10.1101/2023.10.17.562839. | 10.1101/2023.10.17.562839 | https://doi.org/10.1101/2023.10.17.562839 | Medicinal Chemistry | |
| Xu | 32866650 | 2021 | Werth BJ | Dalbavancin exposure in vitro selects for dalbavancin-non-susceptible and vancomycin-intermediate strains of methicillin-resistant Staphylococcus aureus | Clin Microbiol Infect. 2021 Jun;27(6):910.e1-910.e8. doi: 10.1016/j.cmi.2020.08.025. Epub 2020 Aug 28. | 10.1016/j.cmi.2020.08.025 | https://doi.org/10.1016/j.cmi.2020.08.025 | Medicinal Chemistry | |
| Xu | 34179085 | 2021 | Shen T | Varied Contribution of Phospholipid Shedding From Membrane to Daptomycin Tolerance in Staphylococcus aureus | Front Mol Biosci. 2021 Jun 11;8:679949. doi: 10.3389/fmolb.2021.679949. eCollection 2021. | 10.3389/fmolb.2021.679949 | https://doi.org/10.3389/fmolb.2021.679949 | Medicinal Chemistry | |
| Xu | 35510938 | 2022 | Zhang R | Emergence of Dalbavancin, Vancomycin, and Daptomycin Nonsusceptible Staphylococcus aureus in a Patient Treated With Dalbavancin: Case Report and Isolate Characterization | Clin Infect Dis. 2022 Oct 29;75(9):1641-1644. doi: 10.1093/cid/ciac341. | 10.1093/cid/ciac341 | https://doi.org/10.1093/cid/ciac341 | Medicinal Chemistry | |
| Xu | 39936452 | 2025 | Werth BJ | Simulated exposures of oritavancin in in vitro pharmacodynamic models select for methicillin-resistant Staphylococcus aureus with reduced susceptibility to oritavancin but minimal cross-resistance or seesaw effect with other antimicrobials | J Antimicrob Chemother. 2025 Apr 2;80(4):1108-1115. doi: 10.1093/jac/dkaf042. | 10.1093/jac/dkaf042 | https://doi.org/10.1093/jac/dkaf042 | Medicinal Chemistry | |
| Xu | 33472002 | 2021 | Herron JM | Benzalkonium Chloride Disinfectants Induce Apoptosis, Inhibit Proliferation, and Activate the Integrated Stress Response in a 3-D in Vitro Model of Neurodevelopment | Chem Res Toxicol. 2021 May 17;34(5):1265-1274. doi: 10.1021/acs.chemrestox.0c00386. Epub 2021 Jan 20. | 10.1021/acs.chemrestox.0c00386 | https://doi.org/10.1021/acs.chemrestox.0c00386 | Medicinal Chemistry | |
| Xu | 39500386 | 2025 | Raskovic D | Growth of Staphylococcus aureus in the presence of oleic acid shifts the glycolipid fatty acid profile and increases resistance to antimicrobial peptides | Biochim Biophys Acta Biomembr. 2025 Jan;1867(1):184395. doi: 10.1016/j.bbamem.2024.184395. Epub 2024 Nov 3. | 10.1016/j.bbamem.2024.184395 | https://doi.org/10.1016/j.bbamem.2024.184395 | Medicinal Chemistry | |
| Xu | 38045361 | 2025 | Li A | Temporal transcriptomic changes during neurodevelopment in a mouse model of Smith-Lemli-Opitz syndrome | bioRxiv [Preprint]. 2025 Aug 12:2023.11.21.568116. doi: 10.1101/2023.11.21.568116. | 10.1101/2023.11.21.568116 | https://doi.org/10.1101/2023.11.21.568116 | Medicinal Chemistry | |
| Xu | 39957787 | 2025 | Elapavalore A | PubChemLite Plus Collision Cross Section (CCS) Values for Enhanced Interpretation of Nontarget Environmental Data | Environ Sci Technol Lett. 2025 Jan 24;12(2):166-174. doi: 10.1021/acs.estlett.4c01003. eCollection 2025 Feb 11. | 10.1021/acs.estlett.4c01003 | https://doi.org/10.1021/acs.estlett.4c01003 | Medicinal Chemistry | |
| Xu | 41190598 | 2025 | Kula J | Maternal and Placental Inflammation Influence Formation of Neural Tube Defects in Quaternary Ammonium Compound Exposed Mice | Birth Defects Res. 2025 Nov;117(11):e2539. doi: 10.1002/bdr2.2539. | 10.1002/bdr2.2539 | https://doi.org/10.1002/bdr2.2539 | Medicinal Chemistry | |
| Xu | 41506459 | 2026 | Li A | Temporal transcriptomic changes during neurodevelopment in a mouse model of Smith-Lemli-Opitz syndrome | J Steroid Biochem Mol Biol. 2026 Mar;257:106935. doi: 10.1016/j.jsbmb.2026.106935. Epub 2026 Jan 6. | 10.1016/j.jsbmb.2026.106935 | https://doi.org/10.1016/j.jsbmb.2026.106935 | 4/28/26 | Medicinal Chemistry |
| Xu | 38578967 | 2025 | Miller WR | Membrane Lipids Augment Cell Envelope Stress Signaling via the MadRS System to Defend Against Antimicrobial Peptides and Antibiotics in Enterococcus faecalis | J Infect Dis. 2025 Feb 20;231(2):307-317. doi: 10.1093/infdis/jiae173. | 10.1093/infdis/jiae173 | https://doi.org/10.1093/infdis/jiae173 | Medicinal Chemistry | |
| Xu | 40912167 | 2025 | Colonna MB | Expansion of genotype/phenotype correlation in an individual with compound heterozygous variants in CYP51A1 and congenital cataract | Mol Genet Metab. 2025 Sep-Oct;146(1-2):109230. doi: 10.1016/j.ymgme.2025.109230. Epub 2025 Sep 2. | 10.1016/j.ymgme.2025.109230 | https://doi.org/10.1016/j.ymgme.2025.109230 | Medicinal Chemistry |
| PI Association | PMID | Publication Year | First Author | Title | Citation | DOI | Department | ||
|---|---|---|---|---|---|---|---|---|---|
| Nath | 39837577 | 2025 | Tuttle LM | Rigorous Analysis of Multimodal HDX-MS Spectra | J Am Soc Mass Spectrom. 2025 Feb 5;36(2):416-423. doi: 10.1021/jasms.4c00471. Epub 2025 Jan 21. | 10.1021/jasms.4c00471 | https://doi.org/10.1021/jasms.4c00471 | 4/28/26 | Medicinal Chemistry |
| Nath | 42541914 | 2026 | Authement AK | Modeling cortisol and cortisone binding to corticosteroid-binding globulin and albumin based on clinical protein binding data. | Drug Metab Dispos. 2026 Aug;54(8):100362. doi: 10.1016/j.dmd.2026.100362. Epub 2026 Jul 9. | 10.1016/j.dmd.2026.100362 | https://doi.org/10.1016/j.dmd.2026.100362 | 10/14/26 | Medicinal Chemistry |
| Nath | 42039475 | 2026 | Authement AK | Kinetics of cortisol and cortisone binding to corticosteroid binding globulin and albumin in vivo. | bioRxiv [Preprint]. 2026 Apr 17:2026.04.14.718600. doi: 10.64898/2026.04.14.718600. | 10.64898/2026.04.14.718600 | https://doi.org/10.64898/2026.04.14.718600 | 6/26/26 | Medicinal Chemistry |
| Nath | 41899522 | 2026 | Mariano IP | Biophysical and Structural Characterization of Antibody-Drug Conjugates | Cancers (Basel). 2026 Mar 12;18(6):917. doi: 10.3390/cancers18060917. | 10.3390/cancers18060917 | https://doi.org/10.3390/cancers18060917 | Medicinal Chemistry | |
| Nath | 38478383 | 2024 | Wiley AM | Investigating the association between CYP2J2 inhibitors and QT prolongation: a literature review | Drug Metab Rev. 2024 Feb-May;56(2):145-163. doi: 10.1080/03602532.2024.2329928. Epub 2024 Mar 20. | 10.1080/03602532.2024.2329928 | https://doi.org/10.1080/03602532.2024.2329928 | Medicinal Chemistry | |
| Nath | 35147406 | 2022 | Baggett DW | Structure-Activity Relationships of Novel Tau Ligands: Passive Fibril Binders and Active Aggregation Inhibitors | ACS Chem Biol. 2022 Mar 18;17(3):701-708. doi: 10.1021/acschembio.2c00012. Epub 2022 Feb 11. | 10.1021/acschembio.2c00012 | https://doi.org/10.1021/acschembio.2c00012 | Medicinal Chemistry | |
| Nath | 36194135 | 2022 | Kunk C | MitoNEET’s Reactivity of Lys55 toward Pyridoxal Phosphate Demonstrates its Activity as a Transaminase Enzyme | ACS Chem Biol. 2022 Oct 21;17(10):2716-2722. doi: 10.1021/acschembio.2c00572. Epub 2022 Oct 4. | 10.1021/acschembio.2c00572 | https://doi.org/10.1021/acschembio.2c00572 | Medicinal Chemistry | |
| Nath | 38352474 | 2024 | James EI | Tryptanthrin Analogs Substoichiometrically Inhibit Seeded and Unseeded Tau4RD Aggregation | bioRxiv [Preprint]. 2024 Feb 3:2024.02.02.578649. doi: 10.1101/2024.02.02.578649. | 10.1101/2024.02.02.578649 | https://doi.org/10.1101/2024.02.02.578649 | Medicinal Chemistry | |
| Nath | 37861473 | 2023 | Larsen HA | The origins of nonideality exhibited by monoclonal antibodies and Fab fragments in human serum | Protein Sci. 2023 Dec;32(12):e4812. doi: 10.1002/pro.4812. | 10.1002/pro.4812 | https://doi.org/10.1002/pro.4812 | Medicinal Chemistry | |
| Nath | 37562955 | 2023 | Alade N | The Utility of Mixed Effects Models in the Evaluation of Complex Genomic Traits In Vitro | Drug Metab Dispos. 2023 Nov;51(11):1455-1462. doi: 10.1124/dmd.123.001260. Epub 2023 Aug 10. | 10.1124/dmd.123.001260 | https://doi.org/10.1124/dmd.123.001260 | Medicinal Chemistry | |
| Nath | 36948348 | 2023 | Redhair M | Low molecular weight ligands bind to CYP3A4 via a branched induced fit mechanism: Implications for O(2) binding | Arch Biochem Biophys. 2023 May 1;739:109582. doi: 10.1016/j.abb.2023.109582. Epub 2023 Mar 21. | 10.1016/j.abb.2023.109582 | https://doi.org/10.1016/j.abb.2023.109582 | Medicinal Chemistry | |
| Nath | 34384764 | 2021 | Larsen HA | Probing interactions of therapeutic antibodies with serum via second virial coefficient measurements | Biophys J. 2021 Sep 21;120(18):4067-4078. doi: 10.1016/j.bpj.2021.08.007. Epub 2021 Aug 10. | 10.1016/j.bpj.2021.08.007 | https://doi.org/10.1016/j.bpj.2021.08.007 | Medicinal Chemistry | |
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| Xu | 39276938 | 2024 | Hass DT | Acetyl-CoA carboxylase inhibition increases retinal pigment epithelial cell fatty acid flux and restricts apolipoprotein efflux | J Biol Chem. 2024 Oct;300(10):107772. doi: 10.1016/j.jbc.2024.107772. Epub 2024 Sep 12. | 10.1016/j.jbc.2024.107772 | https://doi.org/10.1016/j.jbc.2024.107772 | Medicinal Chemistry | |
| Xu | 38307853 | 2024 | Vieira LS | Interaction and Transport of Benzalkonium Chlorides by the Organic Cation and Multidrug and Toxin Extrusion Transporters | Drug Metab Dispos. 2024 Mar 13;52(4):312-321. doi: 10.1124/dmd.123.001625. | 10.1124/dmd.123.001625 | https://doi.org/10.1124/dmd.123.001625 | Medicinal Chemistry | |
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| Xu | 37425828 | 2023 | Pruitt EL | Elucidating the Impact of Bacterial Lipases, Human Serum Albumin, and FASII Inhibition on the Utilization of Exogenous Fatty Acids by Staphylococcus aureus | bioRxiv [Preprint]. 2023 Jun 30:2023.06.29.547085. doi: 10.1101/2023.06.29.547085. | 10.1101/2023.06.29.547085 | https://doi.org/10.1101/2023.06.29.547085 | Medicinal Chemistry | |
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| Xu | 39363503 | 2024 | Lopez VA | Oral exposure to benzalkonium chlorides in male and female mice reveals alteration of the gut microbiome and bile acid profile | Toxicol Sci. 2024 Dec 1;202(2):265-277. doi: 10.1093/toxsci/kfae116. | 10.1093/toxsci/kfae116 | https://doi.org/10.1093/toxsci/kfae116 | Medicinal Chemistry | |
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| Xu | 41366203 | 2025 | Zhao HN | A resource to empirically establish drug exposure records directly from untargeted metabolomics data | Nat Commun. 2025 Dec 9;16(1):10600. doi: 10.1038/s41467-025-65993-5. | 10.1038/s41467-025-65993-5 | https://doi.org/10.1038/s41467-025-65993-5 | Medicinal Chemistry | |
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| Xu | 35175195 | 2022 | Ting SY | Discovery of coordinately regulated pathways that provide innate protection against interbacterial antagonism | Elife. 2022 Feb 17;11:e74658. doi: 10.7554/eLife.74658. | 10.7554/eLife.74658 | https://doi.org/10.7554/eLife.74658 | Medicinal Chemistry | |
| Xu | 39192580 | 2024 | Weakly HMJ | Several common methods of making vesicles (except an emulsion method) capture intended lipid ratios | Biophys J. 2024 Oct 1;123(19):3452-3462. doi: 10.1016/j.bpj.2024.08.019. Epub 2024 Aug 26. | 10.1016/j.bpj.2024.08.019 | https://doi.org/10.1016/j.bpj.2024.08.019 | Medicinal Chemistry | |
| Xu | 33652836 | 2021 | Pfeffer BA | Transcriptomic Changes Associated with Loss of Cell Viability Induced by Oxysterol Treatment of a Retinal Photoreceptor-Derived Cell Line: An In Vitro Model of Smith-Lemli-Opitz Syndrome | Int J Mol Sci. 2021 Feb 26;22(5):2339. doi: 10.3390/ijms22052339. | 10.3390/ijms22052339 | https://doi.org/10.3390/ijms22052339 | Medicinal Chemistry | |
| Xu | 38746422 | 2024 | Raskovic D | Growth of Staphylococcus aureus in the presence of oleic acid shifts the glycolipid fatty acid profile and increases resistance to antimicrobial peptides | bioRxiv [Preprint]. 2024 May 5:2024.05.03.592415. doi: 10.1101/2024.05.03.592415. | 10.1101/2024.05.03.592415 | https://doi.org/10.1101/2024.05.03.592415 | Medicinal Chemistry | |
| Xu | 37577529 | 2023 | Daggubati V | Hedgehog target genes regulate lipid metabolism to drive basal cell carcinoma and medulloblastoma | Res Sq [Preprint]. 2023 Aug 3:rs.3.rs-3058335. doi: 10.21203/rs.3.rs-3058335/v1. | 10.21203/rs.3.rs-3058335/v1 | https://doi.org/10.21203/rs.3.rs-3058335/v1 | Medicinal Chemistry | |
| Xu | 33868951 | 2021 | Hrubec TC | Altered toxicological endpoints in humans from common quaternary ammonium compound disinfectant exposure | Toxicol Rep. 2021 Mar 9;8:646-656. doi: 10.1016/j.toxrep.2021.03.006. eCollection 2021. | 10.1016/j.toxrep.2021.03.006 | https://doi.org/10.1016/j.toxrep.2021.03.006 | Medicinal Chemistry | |
| Xu | 33476305 | 2021 | Daggubati V | Smoothened-activating lipids drive resistance to CDK4/6 inhibition in Hedgehog-associated medulloblastoma cells and preclinical models | J Clin Invest. 2021 Mar 15;131(6):e141171. doi: 10.1172/JCI141171. | 10.1172/JCI141171 | https://doi.org/10.1172/JCI141171 | Medicinal Chemistry | |
| Xu | 33057715 | 2021 | Shen T | Identification of a novel tedizolid resistance mutation in rpoB of MRSA after in vitro serial passage | J Antimicrob Chemother. 2021 Jan 19;76(2):292-296. doi: 10.1093/jac/dkaa422. | 10.1093/jac/dkaa422 | https://doi.org/10.1093/jac/dkaa422 | Medicinal Chemistry | |
| Xu | 34646861 | 2021 | Zhang R | Synergy Between Beta-Lactams and Lipo-, Glyco-, and Lipoglycopeptides, Is Independent of the Seesaw Effect in Methicillin-Resistant Staphylococcus aureus | Front Mol Biosci. 2021 Sep 9;8:688357. doi: 10.3389/fmolb.2021.688357. eCollection 2021. | 10.3389/fmolb.2021.688357 | https://doi.org/10.3389/fmolb.2021.688357 | Medicinal Chemistry | |
| Xu | 33269585 | 2021 | Do Q | Development and Application of a Peroxyl Radical Clock Approach for Measuring Both Hydrogen-Atom Transfer and Peroxyl Radical Addition Rate Constants | J Org Chem. 2021 Jan 1;86(1):153-168. doi: 10.1021/acs.joc.0c01920. Epub 2020 Dec 3. | 10.1021/acs.joc.0c01920 | https://doi.org/10.1021/acs.joc.0c01920 | Medicinal Chemistry | |
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| Xu | 37904970 | 2023 | Miller WR | Membrane Lipids Augment Cell Envelope Stress Signaling and Resistance to Antibiotics and Antimicrobial Peptides in Enterococcus faecalis | bioRxiv [Preprint]. 2023 Oct 19:2023.10.17.562839. doi: 10.1101/2023.10.17.562839. | 10.1101/2023.10.17.562839 | https://doi.org/10.1101/2023.10.17.562839 | Medicinal Chemistry | |
| Xu | 32866650 | 2021 | Werth BJ | Dalbavancin exposure in vitro selects for dalbavancin-non-susceptible and vancomycin-intermediate strains of methicillin-resistant Staphylococcus aureus | Clin Microbiol Infect. 2021 Jun;27(6):910.e1-910.e8. doi: 10.1016/j.cmi.2020.08.025. Epub 2020 Aug 28. | 10.1016/j.cmi.2020.08.025 | https://doi.org/10.1016/j.cmi.2020.08.025 | Medicinal Chemistry | |
| Xu | 34179085 | 2021 | Shen T | Varied Contribution of Phospholipid Shedding From Membrane to Daptomycin Tolerance in Staphylococcus aureus | Front Mol Biosci. 2021 Jun 11;8:679949. doi: 10.3389/fmolb.2021.679949. eCollection 2021. | 10.3389/fmolb.2021.679949 | https://doi.org/10.3389/fmolb.2021.679949 | Medicinal Chemistry | |
| Xu | 35510938 | 2022 | Zhang R | Emergence of Dalbavancin, Vancomycin, and Daptomycin Nonsusceptible Staphylococcus aureus in a Patient Treated With Dalbavancin: Case Report and Isolate Characterization | Clin Infect Dis. 2022 Oct 29;75(9):1641-1644. doi: 10.1093/cid/ciac341. | 10.1093/cid/ciac341 | https://doi.org/10.1093/cid/ciac341 | Medicinal Chemistry | |
| Xu | 39936452 | 2025 | Werth BJ | Simulated exposures of oritavancin in in vitro pharmacodynamic models select for methicillin-resistant Staphylococcus aureus with reduced susceptibility to oritavancin but minimal cross-resistance or seesaw effect with other antimicrobials | J Antimicrob Chemother. 2025 Apr 2;80(4):1108-1115. doi: 10.1093/jac/dkaf042. | 10.1093/jac/dkaf042 | https://doi.org/10.1093/jac/dkaf042 | Medicinal Chemistry | |
| Xu | 33472002 | 2021 | Herron JM | Benzalkonium Chloride Disinfectants Induce Apoptosis, Inhibit Proliferation, and Activate the Integrated Stress Response in a 3-D in Vitro Model of Neurodevelopment | Chem Res Toxicol. 2021 May 17;34(5):1265-1274. doi: 10.1021/acs.chemrestox.0c00386. Epub 2021 Jan 20. | 10.1021/acs.chemrestox.0c00386 | https://doi.org/10.1021/acs.chemrestox.0c00386 | Medicinal Chemistry | |
| Xu | 39500386 | 2025 | Raskovic D | Growth of Staphylococcus aureus in the presence of oleic acid shifts the glycolipid fatty acid profile and increases resistance to antimicrobial peptides | Biochim Biophys Acta Biomembr. 2025 Jan;1867(1):184395. doi: 10.1016/j.bbamem.2024.184395. Epub 2024 Nov 3. | 10.1016/j.bbamem.2024.184395 | https://doi.org/10.1016/j.bbamem.2024.184395 | Medicinal Chemistry | |
| Xu | 38045361 | 2025 | Li A | Temporal transcriptomic changes during neurodevelopment in a mouse model of Smith-Lemli-Opitz syndrome | bioRxiv [Preprint]. 2025 Aug 12:2023.11.21.568116. doi: 10.1101/2023.11.21.568116. | 10.1101/2023.11.21.568116 | https://doi.org/10.1101/2023.11.21.568116 | Medicinal Chemistry | |
| Xu | 39957787 | 2025 | Elapavalore A | PubChemLite Plus Collision Cross Section (CCS) Values for Enhanced Interpretation of Nontarget Environmental Data | Environ Sci Technol Lett. 2025 Jan 24;12(2):166-174. doi: 10.1021/acs.estlett.4c01003. eCollection 2025 Feb 11. | 10.1021/acs.estlett.4c01003 | https://doi.org/10.1021/acs.estlett.4c01003 | Medicinal Chemistry | |
| Xu | 41190598 | 2025 | Kula J | Maternal and Placental Inflammation Influence Formation of Neural Tube Defects in Quaternary Ammonium Compound Exposed Mice | Birth Defects Res. 2025 Nov;117(11):e2539. doi: 10.1002/bdr2.2539. | 10.1002/bdr2.2539 | https://doi.org/10.1002/bdr2.2539 | Medicinal Chemistry | |
| Xu | 41506459 | 2026 | Li A | Temporal transcriptomic changes during neurodevelopment in a mouse model of Smith-Lemli-Opitz syndrome | J Steroid Biochem Mol Biol. 2026 Mar;257:106935. doi: 10.1016/j.jsbmb.2026.106935. Epub 2026 Jan 6. | 10.1016/j.jsbmb.2026.106935 | https://doi.org/10.1016/j.jsbmb.2026.106935 | 4/28/26 | Medicinal Chemistry |
| Xu | 38578967 | 2025 | Miller WR | Membrane Lipids Augment Cell Envelope Stress Signaling via the MadRS System to Defend Against Antimicrobial Peptides and Antibiotics in Enterococcus faecalis | J Infect Dis. 2025 Feb 20;231(2):307-317. doi: 10.1093/infdis/jiae173. | 10.1093/infdis/jiae173 | https://doi.org/10.1093/infdis/jiae173 | Medicinal Chemistry | |
| Xu | 40912167 | 2025 | Colonna MB | Expansion of genotype/phenotype correlation in an individual with compound heterozygous variants in CYP51A1 and congenital cataract | Mol Genet Metab. 2025 Sep-Oct;146(1-2):109230. doi: 10.1016/j.ymgme.2025.109230. Epub 2025 Sep 2. | 10.1016/j.ymgme.2025.109230 | https://doi.org/10.1016/j.ymgme.2025.109230 | Medicinal Chemistry |
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| Nath | 42541914 | 2026 | Authement AK | Modeling cortisol and cortisone binding to corticosteroid-binding globulin and albumin based on clinical protein binding data. | Drug Metab Dispos. 2026 Aug;54(8):100362. doi: 10.1016/j.dmd.2026.100362. Epub 2026 Jul 9. | 10.1016/j.dmd.2026.100362 | https://doi.org/10.1016/j.dmd.2026.100362 | 10/14/26 | Medicinal Chemistry |
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| Nath | 35147406 | 2022 | Baggett DW | Structure-Activity Relationships of Novel Tau Ligands: Passive Fibril Binders and Active Aggregation Inhibitors | ACS Chem Biol. 2022 Mar 18;17(3):701-708. doi: 10.1021/acschembio.2c00012. Epub 2022 Feb 11. | 10.1021/acschembio.2c00012 | https://doi.org/10.1021/acschembio.2c00012 | Medicinal Chemistry | |
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| Nath | 33057715 | 2021 | Shen T | Identification of a novel tedizolid resistance mutation in rpoB of MRSA after in vitro serial passage | J Antimicrob Chemother. 2021 Jan 19;76(2):292-296. doi: 10.1093/jac/dkaa422. | 10.1093/jac/dkaa422 | https://doi.org/10.1093/jac/dkaa422 | Medicinal Chemistry | |
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