Conducting research in drug metabolism, bio-analytical chemistry and the biophysical characterization of viral protein assembly

The Department of Medicinal Chemistry is part of the highly collaborative, interdisciplinary School of Pharmacy. Medicinal Chemistry is a discipline with a traditional focus on organic synthetic chemistry with the broad goals of drug discovery and optimization. The Department of Medicinal Chemistry has always departed somewhat from this tradition given the focus of many of its faculty on the research areas of mechanistic drug metabolism, toxicology, and bioanalytical chemistry.

Research in medicinal chemistry encompasses a broad spectrum of activities including studies pursuant to investigations of the interaction of both drugs and toxic substances with biological systems, and the relationship of chemical structure and dynamics to biological effect and function. In recent years research activities in the Department have been broadened further by the addition of several faculty members with expertise in the areas of biological mass spectrometry and biophysical virology.

The Graduate Program in Medicinal Chemistry regularly collaborates with the broader University of Washington research community and the considerable biotechnology community in Seattle, to lead many aspects of research in the fields of drug metabolism and disposition, drug design and delivery, and disease mechanism.

Latest Department News

Baughman investigates a natural defense against Alzheimer’s

Hannah Baughman is a PhD student in Medicinal Chemistry, shown here working in the Nath Lab

Hannah Baughman, graduate student in Abhi Nath’s lab, is first author on an article looking at molecular chaperones, which may unlock keys in the fight against neurodegenerative diseases like Alzheimer’s, which seem to be caused by buildup of the protein tau. Hannah was also selected as the Hope Barnes Fellow this year.
“I am honored to rec... Read more



Explore the Department of Medicinal Chemistry