Course Listings

Introduction to drug metabolism and transport pharmacokinetics. Topics include basic processes of drug absorption, distribution and elimination, enzyme/transporter kinetics, associated experimental methodologies for generating kinetic parameter estimates, and principles of drug-drug interactions and other sources of inter-individual variability. Covers experimental rigor and reproducibility and research ethics. Recommended: biochemistry.

Course Master:
Kenneth Thummel
Department of Pharmaceutics
thummel@uw.edu

Provides the student with foundational knowledge of drug properties and interaction with physiology upon administration in vivo, and an understanding of pharmaceutical formulation which is a key disciplinary area within the pharmaceutical sciences and its application to small molecules and protein-based therapeutics.

Course Master:
Rodney Ho
Department of Pharmaceutics
rodneyho@uw.edu

Pharmaceutics and Medicinal Chemistry joint seminars.

PCEUT 520 Seminars will be Thursdays at 12:30 p.m. in K-069, unless noted otherwise. Seminar titles and notices will be posted weekly.

Graduate students attend seminars and make one formal presentation per year while in residence; maximum of three presentations. Credit/no-credit only. Offered: jointly with MEDCH 520.

Provides knowledge base for subsequent pharmacy courses and professional practice. Theory and problems involved in incorporating drugs into stable dosage forms suitable for human use and intended routes of drug administration. Fundamentals of safe and appropriate handling and use of dosage forms. Common dosage forms and basic compounding skills. Recommended: general chemistry.

Course Master:
Qingxin Mu
Department of Pharmaceutics
qmu@uw.edu

Discussion of pertinent articles from current literature and recent laboratory results.

Pharmaceutics and Medicinal Chemistry joint seminars.

PCEUT 520 Seminars will be Thursdays at 12:30 p.m. in K-069, unless noted otherwise. Seminar titles and notices will be posted weekly.

Graduate students attend seminars and make one formal presentation per year while in residence; maximum of three presentations. Credit/no-credit only. Offered: jointly with MEDCH 520.

Covers basic principles of pharmacokinetics and their application to the clinical setting. Includes the design of an appropriate dosing regimen, such as single-dose intravenous and oral administration, multiple dosing, nonlinear pharmacokinetics, metabolite kinetics, pharmacodynamics, inter-individual variability and the physiological basis of pharmacokinetics.

Course Master:
Nina Isoherranen
Department of Pharmaceutics
ni2@uw.edu

Discussion of pertinent articles from current literature and recent laboratory results.

Introduces students to medicinal chemistry and pharmaceutical sciences. Recommended for sophomore, junior and senior students majoring in chemistry, biochemistry, bioengineering, chemical engineering, public health and other health sciences, and related fields. Prerequisite: CHEM 223 or CHEM 237; recommended: basic knowledge in general chemistry and organic chemistry. Offered: jointly with MEDCH 327.

Drug absorption, distribution, excretion, metabolism, and pharmacological effects in mammalian systems. Compartmental and physiologically-based pharmacokinetic models as well as non-compartmental approaches examined. Drug disposition studied in a physiologically realistic context taking nonlinear events into account. Aimed at development of innovative methods for data analysis and evaluation in biological systems. Prerequisite: either PCEUT 506 or permission of instructor. Offered: even years.

Course Master:
Jashvant Unadkat
Department of Pharmaceutics
jash@uw.edu

Provides advance knowledge of the physico-chemical and biological concepts underlying in vivo transport and delivery of drugs. Prerequisite: PCEUT 506. Offered: odd years

Course Master:
Joanne Wang
Department of Pharmaceutics
jowang@uw.edu

Theory and practice. Includes principles of physiological basis of pharmacokinetics, a mechanistic understanding of pharmacokinetic parameters, and the ability to derive basic pharmacokinetic equations and concepts. Prerequisite: either PCEUT 505, PCEUT 531, or permission of instructor.

Course Master:
Nina Isoherranen
Department of Pharmaceutics
ni2@uw.edu

Pharmaceutics and Medicinal Chemistry joint seminars.

PCEUT 520 Seminars will be Thursdays at 12:30 p.m. in K-069, unless noted otherwise. Seminar titles and notices will be posted weekly.

Variation in drug absorption, distribution, elimination, and response, with emphasis on pharmacokinetic-pharmacodynamic relationships. Includes pharmacogenetics, drug-drug interactions, as well as ontogenic and disease state effects and associated precision testing platforms. Uses case studies to integrate possible sources of variation and impact on individual therapeutic decisions. Prerequisite: MEDCH 501; PCEUT 531; and PCEUT 532; recommended: basic understanding of pharmacokinetics and principles of drug absorption, distribution and elimination and drug response.

Course Master:
Kenneth Thummel
Department of Pharmaceutics
thummel@uw.edu

Discussion of pertinent articles from current literature and recent laboratory results.

Current topics in pharmaceuticals and biotechnology focusing on transforming small molecules, proteins, and genes into therapeutic products. Includes new drug therapies, drug design, pharmacogenomics, molecular modeling, high throughput screen, production and stability considerations, and delivery systems of protein and gene therapeutics in relation to pharmacokinetic and therapeutic responses.

Course Master:
Edward Kelly
Department of Pharmaceutics
edkelly@uw.edu