The University of Washington was well-represented at the 21st International Symposium on Microsomes & Drug Oxidations (MDO) held at UC Davis from October 2-6, 2016. Our faculty and alumni researchers presented drug metabolism and related area research during the Parallel Symposia:
- Allan Rettie* (UW Medicinal Chemistry) – CYP2C9 and 4F gene variation in warfarin response & drug interactions
- Bhagwat Prasad (UW Pharmaceutics) – CES1 and CES2: Distribution, function and clinical significance
- Joanne Wang (UW Pharmaceutics) – Importance of OCTs in drug transport
- Nina Isoherranen* (UW Pharmaceutics) – Translation of in vitro biochemical data of vitamin A and retinoid metabolism to tissue specific changes in retinoid concentrations and signaling
- Curtis Klaassen and Julia Yue Cui (UW Environmental and Occupational Health Sciences) – RNA-Seq Quantification of Hepatic Drug-Processing Genes in Germ-Free Mice
- Jeff Jones (UW Medicinal Chemistry ’87, WSU, Chemistry Faculty) – Direct Observation of Cytochrome P450 and Cytochrome P450 Reductase Interacting with Lipid Bilayers
- Cyrus Khojasteh (UW Medicinal Chemistry ’98, Genetech, Drug Metabolism & Pharmacokinetics Associate Director and Senior Scientist) – Current understanding and challenges in the determination of ADME of ADCs
*Session Co-Chair
Other UW School of Pharmacy Alumni present:
Guoying Tai (UW Medicinal Chemistry ’06) – GlaxoSmithKline, Preclinical Drug Metabolism and Pharmacokinetics
Leslie Dickmann (UW Medicinal Chemistry ’03) – Genetech, Preclinical and Translation Pharmacokinetics
John Harrelson (UW Medicinal Chemistry ’05) – Pacific University, School of Pharmacy
Jed Lampe (UW Medicinal Chemistry ’07) – KU Medical Center, Pharmacology, Toxicology & Therapeutics
Clara Hsia (UW Medicinal Chemistry ’12) – Vertex Pharmaceuticals
Kayte Edson (UW Medicinal Chemistry ’13) – Amgen, PKDM
Brooke Rock (UW Medicinal Chemistry ’10) – Amgen, PKDM
Aiming Yu (UW Medicinal Chemistry ’98) was the Chair of the MOC that organized the 21st MDO international conference at UC Davis. Dr. Yu, Associate Professor in the UC Davis Dept of Biochemistry and Molecular Medicine, also directs the PK/PD Bioanalytical Core Facility at UC Davis.
The Keynote Lecture “Mechanism-Based Inactivation of Human Cytochrome P450s” was given by Larry Wienkers (UW Medicinal Chemistry ’93), Vice President at Amgen.
Advance your career in research or pharmacy at the University of Washington!
Click on the links for more information about our Graduate Programs in Medicinal Chemistry, Pharmaceutics, Pharmaceutical Outcomes Research and Policy, and Biomedical Regulatory Affairs.