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Faculty Publications


PI Association Publication Year First Author Title Citation PMID DOI
Nath 2025 Tuttle LM Rigorous Analysis of Multimodal HDX-MS Spectra J Am Soc Mass Spectrom. 2025 Feb 5;36(2):416-423. doi: 10.1021/jasms.4c00471. Epub 2025 Jan 21. 4/28/26 39837577 10.1021/jasms.4c00471
Nath 2026 Mariano IP Biophysical and Structural Characterization of Antibody-Drug Conjugates Mariano IP, Nath A. Biophysical and Structural Characterization of Antibody-Drug Conjugates. Cancers (Basel). 2026 Mar 12;18(6):917. doi: 10.3390/cancers18060917. PMID: 41899522; PMCID: PMC13024996. 41899522 10.3390/cancers18060917
Nath 2024 Wiley AM Investigating the association between CYP2J2 inhibitors and QT prolongation: a literature review Drug Metab Rev. 2024 Feb-May;56(2):145-163. doi: 10.1080/03602532.2024.2329928. Epub 2024 Mar 20. 38478383 10.1080/03602532.2024.2329928
Nath 2022 Baggett DW Structure-Activity Relationships of Novel Tau Ligands: Passive Fibril Binders and Active Aggregation Inhibitors ACS Chem Biol. 2022 Mar 18;17(3):701-708. doi: 10.1021/acschembio.2c00012. Epub 2022 Feb 11. 35147406 10.1021/acschembio.2c00012
Nath 2022 Kunk C MitoNEET's Reactivity of Lys55 toward Pyridoxal Phosphate Demonstrates its Activity as a Transaminase Enzyme ACS Chem Biol. 2022 Oct 21;17(10):2716-2722. doi: 10.1021/acschembio.2c00572. Epub 2022 Oct 4. 36194135 10.1021/acschembio.2c00572
Nath 2024 James EI Tryptanthrin Analogs Substoichiometrically Inhibit Seeded and Unseeded Tau4RD Aggregation bioRxiv [Preprint]. 2024 Feb 3:2024.02.02.578649. doi: 10.1101/2024.02.02.578649. 38352474 10.1101/2024.02.02.578649
Nath 2023 Larsen HA The origins of nonideality exhibited by monoclonal antibodies and Fab fragments in human serum Protein Sci. 2023 Dec;32(12):e4812. doi: 10.1002/pro.4812. 37861473 10.1002/pro.4812
Nath 2023 Alade N The Utility of Mixed Effects Models in the Evaluation of Complex Genomic Traits In Vitro Drug Metab Dispos. 2023 Nov;51(11):1455-1462. doi: 10.1124/dmd.123.001260. Epub 2023 Aug 10. 37562955 10.1124/dmd.123.001260
Nath 2023 Redhair M Low molecular weight ligands bind to CYP3A4 via a branched induced fit mechanism: Implications for O(2) binding Arch Biochem Biophys. 2023 May 1;739:109582. doi: 10.1016/j.abb.2023.109582. Epub 2023 Mar 21. 36948348 10.1016/j.abb.2023.109582
Nath 2021 Larsen HA Probing interactions of therapeutic antibodies with serum via second virial coefficient measurements Biophys J. 2021 Sep 21;120(18):4067-4078. doi: 10.1016/j.bpj.2021.08.007. Epub 2021 Aug 10. 34384764 10.1016/j.bpj.2021.08.007
Nath 2025 James EI Tau4RD fibril polymorphism is imprinted during early aggregation bioRxiv [Preprint]. 2025 Oct 14:2025.10.12.681486. doi: 10.1101/2025.10.12.681486. 41279711 10.1101/2025.10.12.681486
Nath 2020 Vane EW Rapid Formation of Peptide/Lipid Coaggregates by the Amyloidogenic Seminal Peptide PAP(248-286) Biophys J. 2020 Sep 1;119(5):924-938. doi: 10.1016/j.bpj.2020.07.029. Epub 2020 Aug 6. 32814060 10.1016/j.bpj.2020.07.029
Nath 2020 Baughman HER Release of a disordered domain enhances HspB1 chaperone activity toward tau Proc Natl Acad Sci U S A. 2020 Feb 11;117(6):2923-2929. doi: 10.1073/pnas.1915099117. Epub 2020 Jan 23. 31974309 10.1073/pnas.1915099117
Nath 2021 Shen T Identification of a novel tedizolid resistance mutation in rpoB of MRSA after in vitro serial passage J Antimicrob Chemother. 2021 Jan 19;76(2):292-296. doi: 10.1093/jac/dkaa422. 33057715 10.1093/jac/dkaa422
Nath 2024 Yabut KCB Drugs Form Ternary Complexes with Human Liver Fatty Acid Binding Protein (FABP1) and FABP1 Binding Alters Drug Metabolism bioRxiv [Preprint]. 2024 Jan 19:2024.01.17.576032. doi: 10.1101/2024.01.17.576032. 38293009 10.1101/2024.01.17.576032
Nath 2024 Yabut KCB Drugs Form Ternary Complexes with Human Liver Fatty Acid Binding Protein 1 (FABP1) and FABP1 Binding Alters Drug Metabolism Mol Pharmacol. 2024 May 17;105(6):395-410. doi: 10.1124/molpharm.124.000878. 38580446 10.1124/molpharm.124.000878
Nath 2021 Sager JE Corrigendum to "In vitro to in vivo extrapolation of the complex drug-drug interaction of bupropion and its metabolites with CYP2D6; simultaneous reversible inhibition and CYP2D6 downregulation" [Biochem. Pharmacol. 123(2017)85-96] Biochem Pharmacol. 2021 Jan;183:114306. doi: 10.1016/j.bcp.2020.114306. Epub 2020 Nov 5. 33161206 10.1016/j.bcp.2020.114306
Atkins 2020 Redhair M Dynamics and Location of the Allosteric Midazolam Site in Cytochrome P4503A4 in Lipid Nanodiscs Biochemistry. 2020 Feb 18;59(6):766-779. doi: 10.1021/acs.biochem.9b01001. Epub 2020 Jan 27. 31961139 10.1021/acs.biochem.9b01001
Atkins 2020 Lockart MM Multiple drug binding modes in Mycobacterium tuberculosis CYP51B1 J Inorg Biochem. 2020 Apr;205:110994. doi: 10.1016/j.jinorgbio.2020.110994. Epub 2020 Jan 13. 31982812 10.1016/j.jinorgbio.2020.110994
Atkins 2020 Paço L Dynamics and Mechanism of Binding of Androstenedione to Membrane-Associated Aromatase Biochemistry. 2020 Aug 25;59(33):2999-3009. doi: 10.1021/acs.biochem.0c00460. Epub 2020 Aug 11. 32786398 10.1021/acs.biochem.0c00460
Atkins 2021 Clouser AF Cholesterol Asymmetrically Modulates the Conformational Ensemble of the Nucleotide-Binding Domains of P-Glycoprotein in Lipid Nanodiscs Biochemistry. 2021 Jan 12;60(1):85-94. doi: 10.1021/acs.biochem.0c00824. Epub 2020 Dec 22. 33350827 10.1021/acs.biochem.0c00824
Atkins 2021 Redhair M Analytical and functional aspects of protein-ligand interactions: Beyond induced fit and conformational selection Arch Biochem Biophys. 2021 Dec 15;714:109064. doi: 10.1016/j.abb.2021.109064. Epub 2021 Oct 26. 34715072 10.1016/j.abb.2021.109064
Atkins 2022 Clouser AF Long Range Communication between the Drug-Binding Sites and Nucleotide Binding Domains of the Efflux Transporter ABCB1 Biochemistry. 2022 Apr 19;61(8):730-740. doi: 10.1021/acs.biochem.2c00056. Epub 2022 Apr 6. 35384651 10.1021/acs.biochem.2c00056
Atkins 2023 Paço L Nanodisc-embedded cytochrome P450 P3A4 binds diverse ligands by distributing conformational dynamics to its flexible elements J Inorg Biochem. 2023 Jul;244:112211. doi: 10.1016/j.jinorgbio.2023.112211. Epub 2023 Apr 5. 37080138 10.1016/j.jinorgbio.2023.112211
Atkins 2023 Redhair M Low molecular weight ligands bind to CYP3A4 via a branched induced fit mechanism: Implications for O(2) binding Arch Biochem Biophys. 2023 May 1;739:109582. doi: 10.1016/j.abb.2023.109582. Epub 2023 Mar 21. 36948348 10.1016/j.abb.2023.109582
Atkins 2020 Goulet DR Considerations for the Design of Antibody-Based Therapeutics J Pharm Sci. 2020 Jan;109(1):74-103. doi: 10.1016/j.xphs.2019.05.031. Epub 2019 Jun 4. 31173761 10.1016/j.xphs.2019.05.031
Atkins 2020 Goulet DR Design and characterization of novel dual Fc antibody with enhanced avidity for Fc receptors Proteins. 2020 May;88(5):689-697. doi: 10.1002/prot.25853. Epub 2019 Nov 20. 31702857 10.1002/prot.25853
Atkins 2021 Kachapila M Preliminary model assessing the cost-effectiveness of preoperative chlorhexidine mouthwash at reducing postoperative pneumonia among abdominal surgery patients in South Africa PLoS One. 2021 Aug 12;16(8):e0254698. doi: 10.1371/journal.pone.0254698. eCollection 2021. 34383776 10.1371/journal.pone.0254698
Atkins 2021 Larsen HA Probing interactions of therapeutic antibodies with serum via second virial coefficient measurements Biophys J. 2021 Sep 21;120(18):4067-4078. doi: 10.1016/j.bpj.2021.08.007. Epub 2021 Aug 10. 34384764 10.1016/j.bpj.2021.08.007
Atkins 2021 STARSurg Collaborative and COVIDSurg Collaborative Death following pulmonary complications of surgery before and during the SARS-CoV-2 pandemic Br J Surg. 2021 Dec 1;108(12):1448-1464. doi: 10.1093/bjs/znab336. 34871379 10.1093/bjs/znab336
Atkins 2022 STARSurg Collaborative and TASMAN Collaborative Evaluation of prognostic risk models for postoperative pulmonary complications in adult patients undergoing major abdominal surgery: a systematic review and international external validation cohort study Lancet Digit Health. 2022 Jul;4(7):e520-e531. doi: 10.1016/S2589-7500(22)00069-3. 35750401 10.1016/S2589-7500(22)00069-3
Atkins 2020 Atkins WM Mechanisms of promiscuity among drug metabolizing enzymes and drug transporters FEBS J. 2020 Apr;287(7):1306-1322. doi: 10.1111/febs.15116. Epub 2019 Nov 12. 31663687 10.1111/febs.15116
Atkins 2023 Scian M Reversibility and Low Commitment to Forward Catalysis in the Conjugation of Lipid Alkenals by Glutathione Transferase A4-4 Biomolecules. 2023 Feb 9;13(2):329. doi: 10.3390/biom13020329. 36830698 10.3390/biom13020329
Atkins 2023 Larsen HA The origins of nonideality exhibited by monoclonal antibodies and Fab fragments in human serum Protein Sci. 2023 Dec;32(12):e4812. doi: 10.1002/pro.4812. 37861473 10.1002/pro.4812
Bhardwaj 2026 Yang W The past, present and future of de novo protein design Yang W, Wang S, Lee GR, Zhang JZ, Courbet A, Juergens D, Wang X, Schlichthaerle T, Abedi M, Ragotte R, An L, Kalvet I, Pellock S, Mihaljevic L, Glasscock C, Pillai A, Broerman A, Ennist N, Haefner E, McNamara-Bordewick N, Haydon I, Stewart L, Bhardwaj G, Baker D. The past, present and future of de novo protein design. Nature. 2026 Apr;652(8112):1139-1152. doi: 10.1038/s41586-026-10328-7. Epub 2026 Apr 29. PMID: 42056544. 42056544 10.1038/s41586-026-10328-7
Bhardwaj 2026 Luxford JC, Mixed Autoimmune Hemolytic Anemia With Refractory Cold Agglutinin Syndrome in a Child Successfully Treated With Serial Whole Blood Exchange Transfusions and Immunosuppression Luxford JC, Quadir A, Jatana V, Birman C, Bhardwaj G, Woods A, Teo J. Mixed Autoimmune Hemolytic Anemia With Refractory Cold Agglutinin Syndrome in a Child Successfully Treated With Serial Whole Blood Exchange Transfusions and Immunosuppression. J Pediatr Hematol Oncol. 2026 Apr 1;48(3):e128-e133. doi: 10.1097/MPH.0000000000003180. Epub 2026 Mar 2. 4/28/26 41818167 10.1097/MPH.0000000000003180
Bhardwaj 2026 Wankhede L Integrated one-pot ultrasound-assisted method for carotenoid extraction from Rhodosporidium toruloides Wankhede L, Bhardwaj G, Osorio-González CS, Brar SK. Integrated one-pot ultrasound-assisted method for carotenoid extraction from Rhodosporidium toruloides. Bioprocess Biosyst Eng. 2026 Mar 4. doi: 10.1007/s00449-026-03299-6. Epub ahead of print. 4/28/26 41779186 10.1007/s00449-026-03299-6
Bhardwaj 2023 Manna P Accommodative spasm and its different treatment approaches: A systematic review Eur J Ophthalmol. 2023 May;33(3):1273-1286. doi: 10.1177/11206721221136438. Epub 2022 Nov 16. 36384286 10.1177/11206721221136438
Bhardwaj 2022 Bhardwaj G Accurate de novo design of membrane-traversing macrocycles Cell. 2022 Sep 15;185(19):3520-3532.e26. doi: 10.1016/j.cell.2022.07.019. Epub 2022 Aug 29. 36041435 10.1016/j.cell.2022.07.019
Bhardwaj 2023 Rettie SA Cyclic peptide structure prediction and design using AlphaFold bioRxiv [Preprint]. 2023 Feb 26:2023.02.25.529956. doi: 10.1101/2023.02.25.529956. 36865323 10.1101/2023.02.25.529956
Bhardwaj 2024 Rettie SA Accurate de novo design of high-affinity protein binding macrocycles using deep learning bioRxiv [Preprint]. 2024 Nov 18:2024.11.18.622547. doi: 10.1101/2024.11.18.622547. 39605685 10.1101/2024.11.18.622547
Bhardwaj 2025 Rettie SA Accurate de novo design of high-affinity protein-binding macrocycles using deep learning Nat Chem Biol. 2025 Dec;21(12):1948-1956. doi: 10.1038/s41589-025-01929-w. Epub 2025 Jun 20. 40542165 10.1038/s41589-025-01929-w
Bhardwaj 2024 Mahajan BB Bilastine Reimagined: A Comprehensive Exploration of Pruritus Management With a Novel Antihistamine Cureus. 2024 Oct 10;16(10):e71232. doi: 10.7759/cureus.71232. eCollection 2024 Oct. 39525204 10.7759/cureus.71232
Bhardwaj 2023 Muratspahić E Design and structural validation of peptide-drug conjugate ligands of the kappa-opioid receptor Nat Commun. 2023 Dec 6;14(1):8064. doi: 10.1038/s41467-023-43718-w. 38052802 10.1038/s41467-023-43718-w
Bhardwaj 2025 Rettie SA Cyclic peptide structure prediction and design using AlphaFold2 Nat Commun. 2025 May 21;16(1):4730. doi: 10.1038/s41467-025-59940-7. 40399308 10.1038/s41467-025-59940-7
Bhardwaj 2024 Mondal A Binocular Vision Status in Coal Miners Indian J Occup Environ Med. 2024 Jul-Sep;28(3):194-197. doi: 10.4103/ijoem.ijoem_137_23. Epub 2024 Sep 30. 39618904 10.4103/ijoem.ijoem_137_23
Bhardwaj 2023 Ramelot TA Cell-permeable chameleonic peptides: Exploiting conformational dynamics in de novo cyclic peptide design Curr Opin Struct Biol. 2023 Jun;80:102603. doi: 10.1016/j.sbi.2023.102603. Epub 2023 May 12. 37178478 10.1016/j.sbi.2023.102603
Bhardwaj 2024 Wankhede L Technological modes and processes to enhance the Rhodosporidium toruloides based lipid accumulation Microbiol Res. 2024 Oct;287:127840. doi: 10.1016/j.micres.2024.127840. Epub 2024 Jul 16. 39032267 10.1016/j.micres.2024.127840
Bhardwaj 2021 Naredi M Diabetic myonecrosis in end-stage renal disease Natl Med J India. 2021 Jul-Aug;34(4):206-210. doi: 10.25259/NMJI_191_19. 35112543 10.25259/NMJI_191_19
Bhardwaj 2024 Salveson PJ Expansive discovery of chemically diverse structured macrocyclic oligoamides Science. 2024 Apr 26;384(6694):420-428. doi: 10.1126/science.adk1687. Epub 2024 Apr 25. 38662830 10.1126/science.adk1687
Bhardwaj 2025 Gokce-Alpkilic G De Novo Design of High-Affinity Miniprotein Binders Targeting Francisella Tularensis Virulence Factor Angew Chem Int Ed Engl. 2025 Dec 22;64(52):e202516058. doi: 10.1002/anie.202516058. Epub 2025 Oct 21. 41117072 10.1002/anie.202516058
Bhardwaj 2025 Gokce-Alpkilic G De novo design of high-affinity miniprotein binders targeting Francisella tularensis virulence factor bioRxiv [Preprint]. 2025 Jul 5:2025.07.02.662053. doi: 10.1101/2025.07.02.662053. 40631088 10.1101/2025.07.02.662053
Bhardwaj 2023 Azam R The Effect of Illumination on Positive Fusional Vergence Br Ir Orthopt J. 2023 Sep 29;19(1):78-84. doi: 10.22599/bioj.296. eCollection 2023. 37780187 10.22599/bioj.296
Bhardwaj 2024 Mathew J Innovating Ferro-sonication approach for extracting microplastics from wastewater Sci Total Environ. 2024 Nov 15;951:175595. doi: 10.1016/j.scitotenv.2024.175595. Epub 2024 Aug 16. 39154992 10.1016/j.scitotenv.2024.175595
Bhardwaj 2025 Schumacher I Performance analysis of an emergency triage system in ophthalmology using a customized CHATBOT Digit Health. 2025 May 11;11:20552076251320298. doi: 10.1177/20552076251320298. eCollection 2025 Jan-Dec. 40357425 10.1177/20552076251320298
Bhardwaj 2024 Craven TW Computational Design of Cyclic Peptide Inhibitors of a Bacterial Membrane Lipoprotein Peptidase ACS Chem Biol. 2024 May 17;19(5):1125-1130. doi: 10.1021/acschembio.4c00076. Epub 2024 May 7. 38712757 10.1021/acschembio.4c00076
Bhardwaj 2024 Bruce A A Tag-Free Platform for Synthesis and Screening of Cyclic Peptide Libraries Angew Chem Int Ed Engl. 2024 May 21;63(21):e202320045. doi: 10.1002/anie.202320045. Epub 2024 Apr 17. 38529717 10.1002/anie.202320045
Bhardwaj 2025 Karmakar S Cognitive decline, dual sensory loss and the use of visual aids in elderly - A narrative review Oman J Ophthalmol. 2025 Jun 24;18(2):113-120. doi: 10.4103/ojo.ojo_177_23. eCollection 2025 May-Aug. 40666773 10.4103/ojo.ojo_177_23
Bhardwaj 2020 Bloch E Scleral perforation involving the papillomacular bundle secondary to peribulbar anaesthetic injection Am J Ophthalmol Case Rep. 2020 Mar 11;18:100657. doi: 10.1016/j.ajoc.2020.100657. eCollection 2020 Jun. 32195445 10.1016/j.ajoc.2020.100657
Bhardwaj 2021 Anguita R Clinical presentations and surgical outcomes of intraocular foreign body presenting to an ocular trauma unit Graefes Arch Clin Exp Ophthalmol. 2021 Jan;259(1):263-268. doi: 10.1007/s00417-020-04859-6. Epub 2020 Jul 30. 32734467 10.1007/s00417-020-04859-6
Bhardwaj 2024 Mathew J Corrigendum to "Innovating Ferro-sonication approach for extracting microplastics from wastewater" [Sci. Total Environ. (2024) 1-9, 175595] Sci Total Environ. 2024 Dec 1;954:176771. doi: 10.1016/j.scitotenv.2024.176771. Epub 2024 Oct 15. 39406662 10.1016/j.scitotenv.2024.176771
Bhardwaj 2020 Bhardwaj G MANAGEMENT OF GIANT RETINAL TEARS USING TRANSSCLERAL DIODE LASER RETINOPEXY AND SHORT-TERM POSTOPERATIVE TAMPONADE WITH PERFLUORO-N-OCTANE Retina. 2020 Mar;40(3):546-551. doi: 10.1097/IAE.0000000000002424. 30576303 10.1097/IAE.0000000000002424
Bhardwaj 2025 Manna P Effects of Two Vision Therapy Approaches on Accommodative Insufficiency and Post-therapy Stability J Pediatr Ophthalmol Strabismus. 2025 Jan-Feb;62(1):12-26. doi: 10.3928/01913913-20240807-01. Epub 2024 Sep 10. 39254187 10.3928/01913913-20240807-01
Bhardwaj 2020 Merkin R Internal Medicine Resident Work Absence During the COVID-19 Pandemic at a Large Academic Medical Center in New York City J Grad Med Educ. 2020 Dec;12(6):682-685. doi: 10.4300/JGME-D-20-00657.1. Epub 2020 Oct 20. 33391591 10.4300/JGME-D-20-00657.1
Bhardwaj 2025 Bhardwaj G Successful Treatment of Chronic Wound in a Patient with Longstanding Shell Injury on Heel using, a Novel Product Formulation: A Case Report J Orthop Case Rep. 2025 Jan;15(1):17-20. doi: 10.13107/jocr.2025.v15.i01.5108. 39801888 10.13107/jocr.2025.v15.i01.5108
Bhardwaj 2021 Masood S Neuroendocrine Carcinoma of the Colon: Emergency Presentation of a Rare Disease With Poor Biology Cureus. 2021 Nov 14;13(11):e19582. doi: 10.7759/cureus.19582. eCollection 2021 Nov. 34926053 10.7759/cureus.19582
Guttman 2021 Boyoglu-Barnum S Quadrivalent influenza nanoparticle vaccines induce broad protection Nature. 2021 Apr;592(7855):623-628. doi: 10.1038/s41586-021-03365-x. Epub 2021 Mar 24. 33762730 10.1038/s41586-021-03365-x
Guttman 2020 Walls AC Elicitation of Potent Neutralizing Antibody Responses by Designed Protein Nanoparticle Vaccines for SARS-CoV-2 Cell. 2020 Nov 25;183(5):1367-1382.e17. doi: 10.1016/j.cell.2020.10.043. Epub 2020 Oct 31. 33160446 10.1016/j.cell.2020.10.043
Guttman 2024 Cao S Recognition of BACH1 quaternary structure degrons by two F-box proteins under oxidative stress Cell. 2024 Dec 26;187(26):7568-7584.e22. doi: 10.1016/j.cell.2024.10.012. Epub 2024 Nov 5. 39504958 10.1016/j.cell.2024.10.012
Guttman 2025 Watson MJ Defining the Features of Complement-Active IgM J Mol Biol. 2025 Jun 15;437(12):169104. doi: 10.1016/j.jmb.2025.169104. Epub 2025 Mar 26. 40154915 10.1016/j.jmb.2025.169104
Guttman 2021 Mookherjee A Linkage Memory in Underivatized Protonated Carbohydrates J Am Soc Mass Spectrom. 2021 Feb 3;32(2):581-589. doi: 10.1021/jasms.0c00440. Epub 2020 Dec 22. 33350817 10.1021/jasms.0c00440
Guttman 2025 Ferrari ÁJR Large-scale discovery, analysis, and design of protein energy landscapes bioRxiv [Preprint]. 2025 Mar 25:2025.03.20.644235. doi: 10.1101/2025.03.20.644235. 40196533 10.1101/2025.03.20.644235
Guttman 2022 James EI Advances in Hydrogen/Deuterium Exchange Mass Spectrometry and the Pursuit of Challenging Biological Systems Chem Rev. 2022 Apr 27;122(8):7562-7623. doi: 10.1021/acs.chemrev.1c00279. Epub 2021 Sep 7. 34493042 10.1021/acs.chemrev.1c00279
Guttman 2025 Tuttle LM Rigorous Analysis of Multimodal HDX-MS Spectra J Am Soc Mass Spectrom. 2025 Feb 5;36(2):416-423. doi: 10.1021/jasms.4c00471. Epub 2025 Jan 21. 39837577 10.1021/jasms.4c00471
Guttman 2020 Potter ZE Parallel Chemoselective Profiling for Mapping Protein Structure Cell Chem Biol. 2020 Aug 20;27(8):1084-1096.e4. doi: 10.1016/j.chembiol.2020.06.014. Epub 2020 Jul 9. 32649906 10.1016/j.chembiol.2020.06.014
Guttman 2025 Woods CN Activation mechanism of small heat shock protein HSPB5 revealed by disease-associated mutants Proc Natl Acad Sci U S A. 2025 May 20;122(20):e2425061122. doi: 10.1073/pnas.2425061122. Epub 2025 May 16. 40377988 10.1073/pnas.2425061122
Guttman 2023 Woods CN Disordered region encodes α-crystallin chaperone activity toward lens client γD-crystallin Proc Natl Acad Sci U S A. 2023 Feb 7;120(6):e2213765120. doi: 10.1073/pnas.2213765120. Epub 2023 Jan 31. 36719917 10.1073/pnas.2213765120
Guttman 2024 Vorauer C Direct Mapping of Polyclonal Epitopes in Serum by HDX-MS Anal Chem. 2024 Oct 22;96(42):16758-16767. doi: 10.1021/acs.analchem.4c03274. Epub 2024 Oct 10. 39434663 10.1021/acs.analchem.4c03274
Guttman 2022 Reiter KH Cullin-independent recognition of HHARI substrates by a dynamic RBR catalytic domain Structure. 2022 Sep 1;30(9):1269-1284.e6. doi: 10.1016/j.str.2022.05.017. Epub 2022 Jun 17. 35716664 10.1016/j.str.2022.05.017
Guttman 2023 Garcia NK Structural dynamics reveal subtype-specific activation and inhibition of influenza virus hemagglutinin J Biol Chem. 2023 Jun;299(6):104765. doi: 10.1016/j.jbc.2023.104765. Epub 2023 Apr 28. 37121546 10.1016/j.jbc.2023.104765
Guttman 2022 Hale M IgM antibodies derived from memory B cells are potent cross-variant neutralizers of SARS-CoV-2 J Exp Med. 2022 Sep 5;219(9):e20220849. doi: 10.1084/jem.20220849. Epub 2022 Aug 8. 35938988 10.1084/jem.20220849
Guttman 2024 James EI Tryptanthrin Analogs Substoichiometrically Inhibit Seeded and Unseeded Tau4RD Aggregation bioRxiv [Preprint]. 2024 Feb 3:2024.02.02.578649. doi: 10.1101/2024.02.02.578649. 38352474 10.1101/2024.02.02.578649
Guttman 2023 Dosey A Combinatorial immune refocusing within the influenza hemagglutinin RBD improves cross-neutralizing antibody responses Cell Rep. 2023 Dec 26;42(12):113553. doi: 10.1016/j.celrep.2023.113553. Epub 2023 Dec 13. 38096052 10.1016/j.celrep.2023.113553
Guttman 2025 Tuttle LM A framework for automated multimodal HDX-MS analysis bioRxiv [Preprint]. 2025 Mar 15:2025.03.13.643099. doi: 10.1101/2025.03.13.643099. 40161831 10.1101/2025.03.13.643099
Guttman 2025 Mundorff CC Mapping Hydrogen Migration Thresholds for Site-Specific HDX-MS Mol Cell Proteomics. 2025 Nov;24(11):101075. doi: 10.1016/j.mcpro.2025.101075. Epub 2025 Oct 9. 41067539 10.1016/j.mcpro.2025.101075
Guttman 2020 Alonge KM Rapid Differentiation of Chondroitin Sulfate Isomers by Gas-phase Hydrogen-deuterium Exchange Curr Mol Med. 2020;20(10):821-827. doi: 10.2174/1566524020666200915110707. 32933460 10.2174/1566524020666200915110707
Guttman 2025 Vance DJ A type-specific B-cell epitope at the apex of outer surface protein C (OspC) of the Lyme disease spirochete, Borreliella burgdorferi Microbiol Spectr. 2025 Apr;13(4):e0288324. doi: 10.1128/spectrum.02883-24. Epub 2025 Feb 14. 39950825 10.1128/spectrum.02883-24
Guttman 2023 Dosey A Combinatorial immune refocusing within the influenza hemagglutinin head elicits cross-neutralizing antibody responses bioRxiv [Preprint]. 2023 May 24:2023.05.23.541996. doi: 10.1101/2023.05.23.541996. 37292967 10.1101/2023.05.23.541996
Guttman 2025 Rudolph MJ Germline encoded residues dominate the interaction of a human monoclonal antibody with decorin binding protein A of Borrelia burgdorferi Front Immunol. 2025 Jul 7;16:1611828. doi: 10.3389/fimmu.2025.1611828. eCollection 2025. 40692775 10.3389/fimmu.2025.1611828
Guttman 2025 Murphree T Comprehensive Internal Standards for Hydrogen-Deuterium Exchange Mass Spectrometry Anal Chem. 2025 Nov 4;97(43):24217-24224. doi: 10.1021/acs.analchem.5c05191. Epub 2025 Oct 27. 41140027 10.1021/acs.analchem.5c05191
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