
Rutan Zhang
Research Scientist
Department of Medicinal Chemistry, Medicinal Chemistry Research Staff, Xu Lab
Email: rtzhang@uw.edu
Research Scientist
Department of Medicinal Chemistry, Medicinal Chemistry Research Staff, Xu Lab
Email: rtzhang@uw.edu
High-throughput analysis of lipidomic phenotypes of methicillin-resistant Staphylococcus aureus by coupling in situ 96-well cultivation and HILIC-ion mobility-mass spectrometry. Anal Bioanal Chem. 2023 Aug 3. doi: 10.1007/s00216-023-04890-6. Online ahead of print.
Elucidating the Impact of Bacterial Lipases, Human Serum Albumin, and FASII Inhibition on the Utilization of Exogenous Fatty Acids by Staphylococcus aureus. bioRxiv. 2023 Jun 30:2023.06.29.547085. doi: 10.1101/2023.06.29.547085. Preprint.
Differential Contributions of Distinct Free Radical Peroxidation Mechanisms to the Induction of Ferroptosis. JACS Au. 2023 Mar 4;3(4):1100-1117. doi: 10.1021/jacsau.2c00681. eCollection 2023 Apr 24.
Evolution of Enterococcus faecium in Response to a Combination of Daptomycin and Fosfomycin Reveals Distinct and Diverse Adaptive Strategies. Antimicrob Agents Chemother. 2022 Jun 21;66(6):e0233321. doi: 10.1128/aac.02333-21. Epub 2022 May 11.
Emergence of Dalbavancin, Vancomycin, and Daptomycin Nonsusceptible Staphylococcus aureus in a Patient Treated With Dalbavancin: Case Report and Isolate Characterization. Clin Infect Dis. 2022 Oct 29;75(9):1641-1644. doi: 10.1093/cid/ciac341.
Discovery of coordinately regulated pathways that provide innate protection against interbacterial antagonism. Elife. 2022 Feb 17;11:e74658. doi: 10.7554/eLife.74658.
Synergy Between Beta-Lactams and Lipo-, Glyco-, and Lipoglycopeptides, Is Independent of the Seesaw Effect in Methicillin-Resistant Staphylococcus aureus. Front Mol Biosci. 2021 Sep 9;8:688357. doi: 10.3389/fmolb.2021.688357. eCollection 2021.
Development and Application of a Peroxyl Radical Clock Approach for Measuring Both Hydrogen-Atom Transfer and Peroxyl Radical Addition Rate Constants. Do Q, Lee DD, Dinh AN, Seguin RP, Zhang R, Xu L. J Org Chem. 2021 Jan 1;86(1):153-168. doi: 10.1021/acs.joc.0c01920. Epub 2020 Dec 3.
LiPydomics: A Python Package for Comprehensive Prediction of Lipid Collision Cross Sections and Retention Times and Analysis of Ion Mobility-Mass Spectrometry-Based Lipidomics Data. Ross DH, Cho JH, Zhang R, Hines KM, Xu L. Anal Chem. 2020 Nov 17;92(22):14967-14975. doi: 10.1021/acs.analchem.0c02560. Epub 2020 Oct 29.
Proteomic and Metabolic Elucidation of Solar-Powered Biomanufacturing by Bio-Abiotic Hybrid System. Zhang R, He Y, Yi J, Zhang L, Shen C, Liu S, Liu L, Liu B, Qiao L. Chem. 2020 Jan 9;6(1):234-49. doi: 10.1016/j.chempr.2019.11.002