kimberly-m-alonge

Kimberly M. Alonge

Affiliate Assistant Professor

Department of Medicinal Chemistry, Medicinal Chemistry Research Staff, School Faculty

Email: kalonge@uw.edu

Website: PubMed

Expertise:
Central Nervous System, Diabetes, Extracellular Matrices, Glycobiology, Laser Capture Microdissection, Mass Spectrometry, Neuroscience, Translational Research

Taking Students: No

Education

  • B.S. (Biology), Salisbury University
  • Ph.D. (Biochemistry and Molecular Biology), West Virginia University School of Medicine
  • Postdoc (UW Medicine Diabetes Institute, School of Medicine, Division of Metabolism, Endocrinology and Nutrition), University of Washington

Research Interests

  • Perineuronal net reorganization
  • Chondroitin and heparan sulfate glycosaminoglycan sulfation patterning
  • Glycan sequencing technology
  • Obesity, diabetes, Alzheimer’s disease, neuropsychiatric disorders

Recent Publications

Neurocircuit regeneration by extracellular matrix reprogramming. Su S, Levasseur IN, Alonge KM.Neural Regen Res. 2025 Aug 1;20(8):2300-2301. doi: 10.4103/NRR.NRR-D-24-00506. Epub 2024 Sep 6.

Chondroitin sulfate glycan sulfation patterns influence histochemical labeling of perineuronal nets: a comparative study of interregional distribution in human and mouse brain. Belliveau C, Théberge S, Netto S, Rahimian R, Fakhfouri G, Hosdey C, Davoli MA, Hendrickson A, Hao K, Giros B, Turecki G, Alonge KM, Mechawar N.Glycobiology. 2024 Jun 22;34(8):cwae049. doi: 10.1093/glycob/cwae049.

Characterizing the human intestinal chondroitin sulfate glycosaminoglycan sulfation signature in inflammatory bowel disease.Francis KL, Zheng HB, Suskind DL, Murphree TA, Phan BA, Quah E, Hendrickson AS, Zhou X, Nuding M, Hudson AS, Guttman M, Morton GJ, Schwartz MW, Alonge KM, Scarlett JM.Sci Rep. 2024 May 23;14(1):11839. doi: 10.1038/s41598-024-60959-x.

Assessing translational applicability of perineuronal net dysfunction in Alzheimer’s disease across species. Hendrickson AS, Francis KL, Kumar A, Le JP, Scarlett JM, Keene CD, Tovar DA, Alonge KM. Front Neurosci. 2024 Apr 30;18:1396101. doi: 10.3389/fnins.2024.1396101. eCollection 2024. PMID: 38745932

Perineuronal net deglycosylation associates with tauopathy-induced gliosis and neurodegeneration. Logsdon AF, Foresi B, Hu SJ, Quah E, Meuret CJ, Le JP, Hendrickson AS, Redford IK, Kumar A, Phan BA, Doan TP, Noonan C, Hendricks NE, Wheeler JM, Kraemer BC, Alonge KM. J Neurochem. 2024 Feb 5. doi: 10.1111/jnc.16067. Online ahead of print. PMID: 38317026