School of Pharmacy

Kenneth Thummel

Professor

Department of Pharmaceutics, Pharmaceutics Faculty, Pharmacogenomics Research Network, School Faculty

Telephone: (206) 543-0819

Email: thummel@uw.edu

Office Location: H272-M

Website: PubMed

Expertise: Drug Metabolism, Mechanisms-of-Drug-Interactions, Microphysiological organ systems, Nutrition, Pharmacogenomics, Translational Research, Vitamins

Education

  • B.S., Chemistry
  • Ph.D., Pharmaceutical Sciences

Research Interests

  • Drug metabolism kinetics
  • Intestinal first-pass metabolism
  • Mechanisms of inter-individual variability in metabolic drug clearance and drug response
  • Pharmacogenetics
  • Fat soluble vitamins and regulation of DMETs

Courses Taught

  • PCEUT 502
  • PCEUT 506
  • PCEUT 510
  • PCEUT 513
  • PCEUT 534
  • PCEUT 583
  • PCEUT 586
  • MEDCH 527

Biography

Kenneth Thummel received his Ph.D. in Pharmaceutical Science from the University of Washington in 1987 and completed a post-doctoral fellowship in Pharmacology at the University of Connecticut Health Science Center. In 1989, he was appointed to the University of Washington School of Pharmacy faculty, promoted to the rank of Professor in 2001 and was Chairman of the Department of Pharmaceutics between 2006 – 2019. He currently holds the title of Professor of Pharmaceutics and is an Adjunct Professor in the UW Department of Environmental and Occupational Health Sciences. Dr. Thummel’s research interests include the elucidation of genetic, hormonal and environmental factors that contribute to interindividual differences in xenobiotic biotransformation, in particular, intestinal cytochrome P450 3A-mediated first-pass drug metabolism, as well as gene x diet modifiers of drug response in Alaska Native and American Indian people. Dr. Thummel is a Fellow of the American Association for the Advancement of Science and the American Association of Pharmaceutical Scientists, and the recipient of the Rawls-Palmer Progress in Medicine Award from ASCPT. He is a Past-President of the American Society for Pharmacology and Experimental Therapeutics.

Selected Publications

https://www.ncbi.nlm.nih.gov/pubmed/?term=Thummel+K