Jashvant Unadkat

Milo Gibaldi Endowed Professor, Department of Pharmaceutics; Director, UW Research Affiliates Program on Transporters

Department of Pharmaceutics, Pharmaceutics Faculty, UWPKDAP, UWRAPT

Expertise: Drug Interactions, Drug Metabolism, Distribution and Transport, HIV and AIDS, In vitro to in vivo extrapolation, Pharmacokinetics/Pharmacodynamics, Pregnancy and Fetal Pharmacology, Quantitative Targeted Proteomics

Telephone: 206-685-2869

Fax: 206-543-3204

Email: jash@uw.edu

Office Location: Health Science Building Room H-272L

Website: PubMed

Education

  • Postdoctoral fellowship, University of California at San Francisco
  • PhD, University of Manchester
  • BPharm, University of London

Research Interests

  • Mechanisms of drug interactions with antiviral drugs
  • Impact of efflux and influx transporters (e.g. P-glycoprotein, OATPs) on tissue concentrations, efficacy and toxicity of drugs targeted to the brain or the liver
  • Mechanisms of changes in maternal and fetal drug disposition during pregnancy

Biography

Dr. Jashvant “Jash” Unadkat is Professor in the Department of Pharmaceutics and joined the department in 1985. He also holds an adjunct appointment in the Department of Anesthesiology and research affiliate appointments with the UW Center for AIDS and STD Research, Washington National Primate Research Center and the Center for Human Development and Disability. He studies the transport and metabolism of HIV and other antiviral drugs. His research into drug transport could potentially lead to better ways to treat diseases such as Hepatitis C, AIDS and Alzheimer’s.

Dr. Unadkat is the 2012 recipient of the American Association of Pharmaceutical Scientists (AAPS) Research Achievement Award in Pharmacokinetics, Pharmacodynamics and Drug Metabolism. He has previously served as associate editor for the “Journal of Pharmaceutical Sciences,” editor of “AAPS Journal,” and a member of the National Institutes of Health Pharmacology study section. He has published more than 170 peer-reviewed research papers and is a fellow of American Association for the Advancement of Science, AAPS, and Japanese Society for the Study of Xenobiotics. He is the founding chair and member of the focus group of AAPS on Drug Transport and Uptake.

Dr. Unadkat created and leads the UW Research Affiliates Program on Transporters (UWRAPT), a cooperative effort between the UW School of Pharmacy and pharmaceutical companies. He also leads UWPKDAP, a NIDA funded program project grant on drug disposition during pregnancy.” (PubMed.gov)