Chengbo joined the Kelly Lee Lab via  UW BPSD – Biological Physics, Structure & Design



An HIV-1 broadly neutralizing antibody overcomes structural and dynamic variation through highly focused epitope targeting. Hodge, E.A., Chatterjee, A., Chen, C. et al.  npj Viruses 1, 2 (2023).


hACE2-Induced Allosteric Activation in SARS-CoV versus SARS-CoV-2 Spike Assemblies Revealed by Structural Dynamics. Chen C, Zhu R, Hodge EA, Díaz-Salinas MA, Nguyen A, Munro JB, Lee KK. ACS Infect Dis. 2023 May 11. doi: 10.1021/acsinfecdis.3c00010. Online ahead of print.

Three-dimensional ordered DNA network constructed by a biomarker pair for accurate monitoring of colorectal cancer. Chen W, Li T, Chen C, Zhang J, Ma Z, Hou W, Yao Y, Mao W, Liu C, Kong D, Tang S, Shen W. Biosens Bioelectron. 2023 Jul 15;232:115335. doi: 10.1016/j.bios.2023.115335. Epub 2023 Apr 17.

Recent Advances in the Application of Covalent Organic Frameworks in Extraction: A Review. Bagheri AR, Aramesh N, Liu Z, Chen C, Shen W, Tang S. Crit Rev Anal Chem. 2022 Jun 26:1-34. doi:10.1080/10408347.2022.2089838. Online ahead of print.


Mannose-binding lectin and complement mediate follicular localization and enhanced immunogenicity of diverse protein nanoparticle immunogens. Read BJ, Won L, Kraft JC, Sappington I, Aung A, Wu S, Bals J, Chen C, Lee KK, Lingwood D, King NP, Irvine DJ. Cell Rep. 2022 Jan 11;38(2):110217. doi: 10.1016/j.celrep.2021.110217.


Stabilization of the SARS-CoV-2 Spike Receptor-Binding Domain Using Deep Mutational Scanning and Structure-Based Design. Ellis D, Brunette N, Crawford KHD, Walls AC, Pham MN, Chen C, Herpoldt KL, Fiala B, Murphy M, Pettie D, Kraft JC, Malone KD, Navarro MJ, Ogohara C, Kepl E, Ravichandran R, Sydeman C, Ahlrichs M, Johnson M, Blackstone A, Carter L, Starr TN, Greaney AJ, Lee KK, Veesler D, Bloom JD, King NP. Front Immunol. 2021 Jun 29;12:710263. doi: 10.3389/fimmu.2021.710263. eCollection 2021.


Elicitation of Potent Neutralizing Antibody Responses by Designed Protein Nanoparticle Vaccines for SARS-CoV-2.   Walls AC, Fiala B, Schäfer A, Wrenn S, Pham MN, Murphy M, Tse LV, Shehata L, O’Connor MA, Chen C, Navarro MJ, Miranda MC, Pettie D, Ravichandran R, Kraft JC, Ogohara C, Palser A, Chalk S, Lee EC, Guerriero K, Kepl E, Chow CM, Sydeman C, Hodge EA, Brown B, Fuller JT, Dinnon KH 3rd, Gralinski LE, Leist SR, Gully KL, Lewis TB, Guttman M, Chu HY, Lee KK, Fuller DH, Baric RS, Kellam P, Carter L, Pepper M, Sheahan TP, Veesler D, King NP. in Cell. 2020 Nov 25;183(5):1367-1382.e17. Epub 2020 Oct 31.


Magnetic Ni/Fe layered double hydroxide nanosheets as enhancer for DNA hairpin sensitive detection of miRNA. Sun J, Li Y, Chen C, Qi T, Xia D, Mao W, Yang T, Chen L, Shen W, Tang S. Talanta. 2018 Sep 1;187:265-271. doi: 10.1016/j.talanta.2018.05.037. Epub 2018 May 9.