School of Pharmacy

Catherine Yeung

Assistant Professor, Department of Pharmacy Investigator, Kidney Research Institute, Division of Nephrology

Department of Pharmacy, Pharmacy Faculty, School Faculty

Telephone: (206) 685-1075

Email: cathyy@uw.edu

Office Location: H375E Health Sciences Building Box 357630 1959 NE Pacific St Seattle WA 98195

Expertise: Analytical Techniques, Chronic Disease, Drug Discovery, Drug Metabolism, Drug Transporters, Mechanisms-of-Drug-Interactions, Medication Use in Patients with Organ Impairment, Microphysiological organ systems, Translational Research

Education

  • PhDPharmD (University of Michigan)
  • PhD, Medicinal Chemistry (University of Washington)
  • MPH, Epidemiology (University of Washington)

Research Interests

  • Optimizing medication use in patients with Chronic Kidney Disease
  • Microfluidic models of kidney function in health and disease
  • Effects of uremia on drug transport and pharmacokinetics
  • Effects of microgravity on kidney structure and function

Courses Taught

  • PHARM 560
  • PHARM 579
  • PHARM 301
  • PCEUT 586
  • PCEUT 506
  • PHARBE 522

Biography

Dr. Yeung’s research includes both basic science and translational studies, and spans from the determination of molecular mechanisms of altered drug metabolism using 3-dimensional cell culture techniques to the evaluation of the effect of drugs and nutritional supplements on health outcomes in patients receiving hemodialysis. She is a key investigator in the development of a “kidney on a chip” microphysiological system that can be used in preclinical drug development.

Selected Publications

  • Kidneys on Chips: Emerging Technology for Preclinical Drug Development (PMID: 30274990)
  • Human liver-kidney model elucidates the mechanisms of aristolochic acid nephrotoxicity (PMID: 29202460)
  • Does Secretory Clearance Follow Glomerular Filtration Rate in Chronic Kidney Diseases? Reconsidering the Intact Nephron Hypothesis (PMID: 28675584)
  • Effects of chronic kidney disease and uremia on hepatic drug metabolism and transport (PMID: 24132209)
  • Development of a microphysiological model of human kidney proximal tubule function (PMID: 27521113)