School of Pharmacy

Beth Devine

Professor, The CHOICE Institute Adjunct Professor: Health Services, Biomedical Informatics, Surgery Member: Institute for Public Health Genetics

CHOICE Faculty, Department of Pharmacy, Institute for Innovative Pharmacy Practice, Pharmacogenomics Research Network, Pharmacy Faculty, Plein Center in Geriatrics Faculty, School Faculty

Telephone: (425) 891-8074

Email: bdevine@uw.edu

Office Location: H-375-D Box 357630 1959 NE Pacific St Seattle ,WA 98195-7630

Website: PubMed

Expertise: Chronic Disease, Claims Data, Comparative Effectiveness Research, Cost Effectiveness Research, Economic Evaluation, Health Economics, Health Outcomes, Health Services Research, Managed Care Pharmacy, Medication Safety, Pharmaceutical and health outcomes research, Pharmacogenomics, Practice-based Research, Preference Elicitation, Real World Data Methods, Systematic Reviews of Evidence

Education

  • Post-doctoral Fellowship, The CHOICE Institute, UW and Roche Global Pharma Business
  • PhD, Health Services Research, UW
  • MBA, University of San Francisco
  • PharmD, University of the Pacific
  • Clinical Pharmacy Residency, Palo Alto VA Medical Center

Research Interests

  • Pharmacogenomic-guided medication safety;
  • Clinical informatics;
  • Comparative effectiveness research using real world data;
  • Evidence synthesis

Courses Taught

  • Pharm 535/HServ 584 – Assessing Outcomes in Health & Medicine;
  • Pharm 592 – Design and Analysis of Medical Studies
  • Pharm 514 – Design and Analysis of Medical Studies
  • HECON – Health Technology Asssessment

Biography

Dr. Devine is a health services research scientist and health economist who employs methods from the overlapping disciplines of epidemiology, biostatistics , decision sciences and clinical informatics . The framework for her work is comparative effectiveness research . Her foremost area of research is evidence synthesis, wherein she has conducted over 25 systematic reviews and network meta-analyses in both the frequentist and Bayesian frameworks.

She is the Assistant Director and site-principal investigator of the AHRQ-funded Pacific Northwest Evidence-based Practice Center (EPC) V, which brings together the strengths of faculty and staff from UW, Oregon Health & Science University, and Aggregate Analytics, Inc. She is an elected member of the Society for Research Synthesis Methodology and was a key contributor to the International Society for Pharmacoeconomics and Outcomes Research (ISPOR) Task Force that developed the Good Research Practices for Conducting Indirect Treatment Comparisons, considered a tool for conducting CER.

Dr. Devine also has expertise in the conduct of prospective studies, retrospective database analyses, and cost-effectiveness analyses. She employs these study designs to investigate issues of pharmacogenomic-guided medication safety, healthcare resource use, costs and value of healthcare interventions. Prior to launching her research career, Dr. Devine practiced clinical pharmacy with advanced practice (prescribing) privileges, and served in administrative positions related to formulary management, medication safety and quality improvement, in both academic (UCSF) and community medical center settings.

 

Selected Publications

  • Hart MR, Garrison LP, Doyle DL, Jarvik GP, Watkins J, Devine B. Projected cost-effectiveness for two gene-drug pairs using a multi-gene panel for patients undergoing percutaneous coronary intervention. (under revision at Value Health; April 2019)
  • Bounthavong M, Devine EB, Christopher MLD, Harvey MA, Veenstra DL, Basu A. National implementation of academic detailing service on naloxone prescribing trends at the United States Department of Veterans Affairs: A retrospective cohort study. (under revision at Health Serv Res; April 2019)
  • Thompson M, Hardy V, Suchsland MZ, Devine B, Kurth D, chou R, Haines R, Jarvik JG, for the PROD Research Group. A secondary analysis to identify patient-centered outcomes in the American College of Radiology’s Appropriateness Criteria. (in press at the J Amer Coll Rad; May 2019)
  • Mercieca- Bebber R, Williams D, Tait MA, Roydhouse J, Busija L, Sundaram CS, Wilson M, Langford A, Rutherford C, Roberts N, King M, Vodicka E, Devine B, on behalf of the International Society for Quality of Life Research (ISOQOL). Trials with patient-reported outcomes registered on the Australian New Zealand Clinical Trials Registry (ANZCTR). Qual Life Res, June 2018. https://doi.org/10.1007/s11136-018-1921-5
  • McDermott C, Lockhart C, Devine EB. Outpatient directly observed therapy for hepatitis C among people who inject drugs: a systematic review and meta-analysis. (J Virus Erad. 2018 Apr 1;4(2):118-122
  • Devine EB, Van Eaton E, Zadworny ME, Symons R, Devlin A, Yanez D, et al. Automating Electronic Clinical Data Capture for Quality Improvement and Research: The CERTAIN Validation Project of Real World Evidence. eGEMs (Generating Evidence & Methods to improve patient outcomes) . 2018; 6 (1) :8 . pp. 1-11. PMID: 29881766. DOI: http://doi.org/10.5334/egems.211
  • Devine EB, Perfetto E, Pickard AS, Schumock GT, Segal JB, Brixner D, Cannon E, Gagnon JP, Garrison LP, Murray, MD. Nine Years of Comparative Effectiveness Research Education and Training: Initiative Supported by the PhRMA Foundation. J. Comp. Eff. Res. 2018;7:167-175. PMID: 29464964. doi: 10.2217/cer-2017-0059. Epub 2018 Feb 21.
  • Devine EB, Hersh W, Totten A, Eden K, Gorman P, Kassakian S, Woods S, Daeges M, Pappas M, McDonagh M. Use of health information exchange. eGEMS, 2017, Vol 5, Iss 1
  • Devine, Beth (2017) “Concordium 2016: Data and Knowledge Transforming Health,” eGEMs (Generating Evidence & Methods to improve patient outcomes): Vol. 5: Iss. 2, Article 9. DOI: https://doi.org/10.13063/2327-9214.1306 Available at: http://repository.edm-forum.org/egems/vol5/iss2/9
  • Viswanathan M, McPheeters ML, Murad MH, Butler ME, Devine EB, Dyson MP, Guise JM, Kahwati LC, Miles JNV, Morton SC. AHRQ series on complex intervention systematic reviews-paper 4: selecting analytic approaches. J Clin Epidemiol. 2017 Jul 15. pii: S0895-4356(17)30639-X. doi: 10.1016/j.jclinepi.2017.06.014. [Epub ahead of print]
  • Pigott T, Noyes J, Umscheid CA, Myers E, Morton SC, Fu R, Sanders-Schmidler GD, Devine B, Murad MH, Kelly MP, Fonnesbeck C, Kahwati L, Beretvas SN. AHRQ series on complex intervention systematic reviews-paper 5: advanced analytic methods. J Clin Epidemiol. 2017 Jul 15. pii: S0895-4356(17)30640-6. doi: 10.1016/j.jclinepi.2017.06.015. [Epub ahead of print]
  • Canestaro WJ, Hendrix N, Bansal A, Sullivan SD, Devine EB, Carlson JJ. Favorable and Publicly-Funded Studies are More Likely to be Published: A Systematic Review and Meta-Analysis. J Clin Epidemiol. 2017;92:58-68. PMID: 28842289. doi: 10.1016/j.jclinepi.2017.08.004. Epub 2017 Aug 31
  • Mathias PC, Hendrix N, Wang WJ, Keyloun KR, Khelifi M, Tarczy-Hornoch P, Devine B. Characterizing pharmacogenomic-guided medication use with a clinical data repository. Clin Pharmacol Ther. 2017 Aug;102(2):340-348. doi: 10.1002/cpt.611. Epub 2017 Jun 5.
  • Chin L, Devine B, Baradaran S, Keyloun K, Canestaro WJ, Pham J. Characterizing the strength of evidence in FDA Labels for pharmacogenomic biomarker-guided medication use. AMIA Jt Summits Transl Sci Proc. 2017 Jul 26;2017:30-39. eCollection 2017