School of Pharmacy

Amy Li

Graduate Student

Department of Medicinal Chemistry, Medicinal Chemistry Students, Xu Lab

Email: ali94@uw.edu

Publications

7-Dehydrocholesterol-derived oxysterols cause neurogenic defects in Smith-Lemli-Opitz syndrome. Tomita H, Hines KM, Herron JM, Li A, Baggett DW, Xu L. Elife. 2022 Sep 16;11:e67141. doi: 10.7554/eLife.67141. Online ahead of print.

CNPY4 inhibits the Hedgehog pathway by modulating membrane sterol lipids. Lo M, Sharir A, Paul MD, Torosyan H, Agnew C, Li A, Neben C, Marangoni P, Xu L, Raleigh DR, Jura N, Klein OD. Nat Commun. 2022 May 3;13(1):2407. doi: 10.1038/s41467-022-30186-x.

Temporal changes in the brain lipidome during neurodevelopment of Smith-Lemli-Opitz syndrome mice. Li A, Hines KM, Ross DH, MacDonald JW, Xu L. Analyst. 2022 Apr 11;147(8):1611-1621. doi: 10.1039/d2an00137c.

Smoothened-activating lipids drive resistance to CDK4/6 inhibition in Hedgehog-associated medulloblastoma cells and preclinical models. Daggubati V, Hochstelter J, Bommireddy A, Choudhury A, Krup AL, Kaur P, Tong P, Li A, Xu L, Reiter JF, Raleigh DR. J Clin Invest. 2021 Mar 15;131(6):e141171. doi: 10.1172/JCI141171.

Lipidomics by HILIC-Ion Mobility-Mass Spectrometry. Li A, Hines KM, Xu L. Methods Mol Biol. 2020;2084:119-132. doi: 10.1007/978-1-0716-0030-6_7.PMID: 31729657 Free PMC article.

Sterol and oxysterol synthases near the ciliary base activate the Hedgehog pathway. Findakly S, Daggubati V, Garcia G, LaStella SA, Choudhury A, Tran C, Li A, Tong P, Garcia JQ, Puri N, Reiter JF, Xu L, Raleigh DR. J Cell Biol. 2021 Jan 4;220(1):e202002026. doi: 10.1083/jcb.202002026. PMID: 33284321

Resistome of Staphylococcus aureus in Response to Human Cathelicidin LL-37 and Its Engineered Antimicrobial Peptides. Golla RM, Mishra B, Dang X, Lakshmaiah Narayana J, Li A, Xu L, Wang G. ACS Infect Dis. 2020 Jul 10;6(7):1866-1881. doi: 10.1021/acsinfecdis.0c00112. Epub 2020 May 11.PMID: 32343547

Nitric acid acts upon copper: Gas phase product analysis of a historic reaction using Fourier Transform Infrared Spectroscopy. Sytsma T, Li A, Ganske JA. (2018) The Chemical Educator, 23: 58-63.

Quantifying tetrodotoxin levels in the California newt using a non-destructive samplingmethod. Bucciarelli GM, Li A, Zimmer RK, Kats LB, Green DB. Toxicon. 2014 Mar;80:87-93. Epub 2014 Jan 24. Erratum in: Toxicon. 2015 Jun 1;99:146. Zimmer, Richard K [added].