Klarissa Jackson, ’13, has been awarded an ASPET 2022 Division for Translational and Clinical Pharmacology Early Career Award which recognizes excellence in translational and clinical pharmacology research developed by early-career scientists.
A 2013 UW School of Pharmacy postdoctoral fellow in the Department of Medicinal Chemistry, Dr. Jackson currently serves as assistant professor at UNC Eshelman School of Pharmacy in Pharmacotherapy and Experimental Therapeutics in Chapel Hill, NC.
Dr. Jackson received the award based on her translational research in drug metabolism/toxicology, focusing specifically on individual variations in cytochrome P450 enzymes. Her laboratory, supported by funding from the NIH National Cancer Institute Center to Reduce Cancer Health Disparities, the National Institute of General Medical Sciences, and the American Association of Colleges of Pharmacy, is focused on the roles of P450 and non-P450 enzymes in the metabolism and toxicity of small molecule drugs used in targeted cancer therapy.
Dr. Jackson is interested in understanding the impact of variability in drug metabolism and the disposition on individual risk for drug toxicity. Long-term, the goal of her research is to better predict and prevent adverse drug reactions and optimize drug therapy in diverse patient populations.
This award will be presented by the Division for Translational and Clinical Pharmacology at the ASPET annual meeting on April 4, 2022. There, Dr. Jackson will deliver a lecture on her research titled, Studies on the Role of Metabolic Activation in Tyrosine Kinase Inhibitor-Dependent Hepatotoxicity.