School of Pharmacy


Critical Differences between Enzyme Sources in Sensitivity to Detect Time-Dependent Inactivation of CYP2C8. Kahma H, Filppula AM, Launiainen T, Viinamäki J, Neuvonen M, Evangelista EA, Totah RA, Backman JT. Drug Metab Dispos. 2019 Apr;47(4):436-443. doi: 10.1124/dmd.118.085498. Epub 2019 Feb 1.

Regulation of CYP2J2 and EET Levels in Cardiac Disease and Diabetes. Aliwarga T, Evangelista EA, Sotoodehnia N, Lemaitre RN, Totah RA. Int J Mol Sci. 2018 Jun 29;19(7). pii: E1916. Review.

CYP2J2 Expression in Adult Ventricular Myocytes Protects Against Reactive Oxygen Species Toxicity. Evangelista EA, Lemaitre RN, Sotoodehnia N, Gharib SA, Totah RA. Drug Metab Dispos. 2018 Apr;46(4):380-386. Epub 2018 Jan 17.

Activity, inhibition, and induction of cytochrome P450 2J2 in adult human primary cardiomyocytes. Evangelista EA, Kaspera R, Mokadam NA, Jones JP 3rd, Totah RA. Drug Metab Dispos. 2013 Dec;41(12):2087-94. Epub 2013 Sep 10.

Drug metabolism by CYP2C8.3 is determined by substrate dependent interactions with cytochrome P450 reductase and cytochrome b5. Kaspera R, Naraharisetti SB, Evangelista EA, Marciante KD, Psaty BM, Totah RA. Biochem Pharmacol. 2011 Sep 15;82(6):681-91. Epub 2011 Jun 24.