David Plotnik

Graduate Student

Department of Pharmaceutics, Pharmaceutics Students

Telephone: (206) 543-3844

Email: dplotnik@uw.edu

Advisor: Shiu-Lok Hu

Year Admitted: 2012


I study the interaction between HIV and α4β7+ T cells, a cell type which is believed to play significant roles in HIV disease.  I have discovered that the extracellular matrix protein fibronectin facilitates infection of α4β7+ T cells by HIV.  This suggests a role for fibronectin in HIV pathogenesis, and identifies novel ways to target HIV-α4β7 interactions therapeutically.