Job Opportunities

The University of Washington, Department of Pharmaceutics currently has an outstanding opportunity for a Postdoctoral Research Associate to join our NIAID-funded Targeted Long-acting Combination Anti-Retroviral Therapy (TLC-ART) research program.

The Associate will be a key member of a project team to provide pharmacokinetic modeling support for a coordinated set of formulation development studies that include 1) in vitro assessment of drug release from nanoparticle formulations, 2) disposition kinetics in blood, lymph and tissues across rodents and non-human primate species, and 3) characterization of lymphatic circulatory physiology by novel imaging studies in animal models.

The Associate is expected to:

  • Participate in the framing and design of the pharmacokinetic analysis plan
  • Coordinate the assembly and organization of the data set
  • Work with the project team in implementing the pharmacokinetic modeling
  • Coordinate the interpretation and reporting of the modeling results

The applicant should have previous training and research experience in kinetic modeling of biological processes. Experience with modeling in pharmacokinetics, pharmacodynamics and facility in the use of one or more pharmacokinetic modeling software applications are highly desirable. The applicant needs to have relevant educational background and knowledge to assume an effective, collaborative role within an interdisciplinary mix of basic and clinical scientists in formulation science, pharmacology, immunology, infectious diseases, mathematics, biostatistics, and bioanalysis. Good written and oral communication and organizational skills are essential.

REQUIREMENTS:

  • PhD in pharmaceutical sciences, bioengineering, physiology, biophysics, biochemistry, or equivalent
  • Strong background in pharmacokinetic and pharmacometric principles
  • Ability to prioritize and manage multiple overlapping projects
  • Effective written and oral communication skills
  • Attention to detail and good organizational skills

Equivalent education/experience will substitute for all minimum qualifications.

DESIRED:

  • Experience with modeling software packages, such as Phoenix Modeling & Simulation, NONMEM, SAAM II, SimCyp, GastroPlus MATLAB, and R
  • Strong motivation, collaborative spirit and positive attitude

CONTACT:
Please send a letter of application including the names of three references and the earliest date of availability for this postdoctoral position, along with a current curriculum vitae to Drs. Rodney Ho and Danny Shen at tlcart@uw.edu. The position will remain open until filled by a qualified candidate. For more information about the TLC-ART program please visit our website: http://depts.washington.edu/tlcart/


POSTDOCTORAL POSITION

Department of Pharmaceutics, University of Washington Seattle, WA, USA

Overview

A postdoctoral position is available in the laboratory of Dr. Bhagwat Prasad at University of Washington (UW), Seattle, WA in the area of pediatric physiologically-based pharmacokinetic (PBPK) modeling. The laboratory is working on mechanisms of age-dependent variability in drug disposition and response towards pediatric precision medicine. The NIH funded translational research project will utilize interdisciplinary approaches such as in vitro drug metabolism and transport studies, bioanalysis of drugs and enzymes/transporters in biological matrices by quantitative mass spectrometry, clinical PK analysis and PBPK/PD modeling. The candidate is expected to have prior experience of PBPK software tools e.g., Phoenix WinNonlin, SimCyp or Matlab with familiarity to standard in vitro drug metabolism/transport techniques. The successful candidate will develop and execute experimental procedures, interpret data, present results at scientific conferences and prepare manuscripts for publication. The candidate will have the ability to work both independently and as part of a team. Exciting research environment, state-of-the-art equipment/software and facilities are available at UW School of Pharmacy. This position is available for two years with the possibility of extension.

Qualification

A Ph.D. degree in pharmacokinetics, drug metabolism, drug transport or bioanalysis is required. The applicant must have at least one first-author publication in peer-reviewed journals to be considered.

How to Apply
Please send a letter summarizing previous work experience and future interests, a resume, and contact information for three references to: Dr. Bhagwat Prasad, Assistant Professor, Department of Pharmaceutics, UW (bhagwat@uw.edu) (website: http://depts.washington.edu/qpromics/).


POSTDOCTORAL POSITION, UNIVERSITY OF WASHINGTON, SEATTLE, WA

Applications are invited for a postdoctoral position in the laboratory of Nichole Klatt at the University of Washington in Seattle, WA. Dr. Klatt’s research lab focuses on understanding mechanisms underlying mucosal dysfunction and microbiome dysbiosis during HIV infection, and developing novel therapeutic interventions to treat HIV disease pathogenesis and prevent HIV acquisition.  The lab uses both HIV human studies and non-human primate models of SIV infection to assess these questions.

Highly motivated scientists with a background in immunology, microbiology, virology, cell biology, molecular biology or similar are encouraged to apply. Candidates with backgrounds in HIV research, microbiome, mucosal immunology, vaccinology or microbiology will be preferred.

Advanced training and experience in multi-color flow cytometry, including FACS analysis and interpretation OR in microbiome sequencing and analysis required. Training in PCR, high throughput sequencing, ELISA, cell culture, and tissue processing preferred. Experience in mucosal immunology and non-human primate or human mucosal tissue processing and research preferred. Experience in microbiome sequencing and/or analysis preferred.

Candidates should have expertise in data analysis, using the computer programs excel, prism, flowjo, QIIME, R, Mothur and adobe illustrator or equivalent programs. Manuscript and figure preparation, grant writing skills, and a strong publication record required.

Please contact directly:

Nichole R. Klatt, PhD
University of Washington
Assistant Professor
Department of Pharmaceutics
Adjunct Assistant Professor
Cellular and Molecular Biology Program
Pathobiology Program
WaNPRC
3018 Western Avenue
Seattle, WA 98121
klattnr@uw.edu

 


The University of Washington is committed to enhancing diversity among our students, staff, and faculty, and is an Affirmative Action, Equal Opportunity Employer.