| Manufacturer |
Agilent Technologies, Santa Clara, CA, USA |
| *Mass range: |
~ 20-20000 Daltons (TOF) |
| *Resolution: |
Up to 40,000 mass resolution, sub-1-ppm MS and 2-ppm MS/MS mass accuracy |
| Ionization (±eV): |
- Agilent Jet Stream Technology, Orthogonal Spray Ionization Source
- Electrospray & Atmospheric Pressure Chemical Ionization
|
| Detectors: |
- MS/MS using a quadrupole, a hexapole – collision cell – and a time-of-flight (TOF)
- Up to 20 MS or 10 MS/MS spectra per second (32 Gbit/sec data acquisition system)
|
| Inlet Systems: |
- Liquid Chromatograph (LC)
- Agilent Technologies Series 1200 binary solvent delivery system
- Thermostated auto sampler compartment (vials & 96 well plates)
- (Agilent Technologies, Palo Alto, CA)
|
| Data System (DS): |
- Microsoft Windows 7
- MassHunter Data Acquisition and Processing
|
| Acquisition Date: |
2009 |
| Funding: |
ITHS, Dept of Pharmacy, Dept of Pharmaceutics, Dean of Pharmacy |
| Predominant Uses: |
- Data dependent LC/MS/MS proteomic analysis
- Metabonomic profiling and biomarker discovery/validation
- Increased specificity and sample definition by combining accurate mass measurement with quadrupole time-of-flight (Q-TOF) mass spectrometry
|