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David Goodlett

Professor David Goodlett
Affiliate Professor, Medicinal Chemistry

PH: 206 616 4586


  • B.S., 1982, Auburn University, Alabama
  • M.S., 1988, Auburn University, Alabama
  • Ph.D., 1991, North Carolina State University


  • Chu LJ, Yang H, Shih P, Kao Y, Tsai YS, Chen J, Huang G, Weng RR, Ting YS, Fang X, von Haller PD, Goodlett DR, Ng WV. "Metabolic Capabilities and Systems Fluctuations in Haloarcula marismortui Revealed by Integrative Genomics and Proteomics Analyses." J Proteome Res, 10(7), 3261-73, 2011.
  • Thatcher JE, Buttrick B, Shaffer SA, Shimshoni JA, Goodlett DR, Nelson WL, Isoherranen N. "Substrate specificity and ligand interactions of CYP26A1, the human liver retinoic acid hydroxylase." Mol Pharmacol, online, 2011.
  • Ting YS, Shaffer SA, Jones JW, Ng WV, Ernst RK, Goodlett DR. "Automated lipid a structure assignment from hierarchical tandem mass spectrometry data." J Am Soc Mass Spectrom, 22(5), 856-66, 2011.
  • Yu L, Tan Y, Tsai Y, Goodlett DR, Polfer NC. "On the relevance of peptide sequence permutations in shotgun proteomics studies." J Proteome Res, 10(5), 2409-16, 2011.
  • Devic I, Hwang H, Edgar JS, Izutsu K, Presland R, Pan C, Goodlett DR, Wang Y, Armaly J, Tumas V, Zabetian CP, Leverenz JB, Shi Mu, Zhang J. "Salivary {alpha}-synuclein and DJ-1: potential biomarkers for Parkinson's disease." Brain, 134 (pt 7), e178, 2011.
  • Panchaud A, Jung S, Shaffer SA, Aitchison JD, Goodlett DR. "Faster, quantitative, and accurate precursor acquisition independent from ion count." Anal Chem, 83(6), 2250-7, 2011.
  • Mealman TD, Bagai I, Singh P, Goodlett DR, Rensing C, Zhou H, Wysocki VH, McEvoy MM. "Interactions between CusF and CusB identified by NMR spectroscopy and chemical cross-linking coupled to mass spectrometry." Biochemistry, 50(13), 2559-66, 2011.
  • Fang X, Yoon JG, Li L, Tsai YS, Zheng S, Hood L, Goodlett DR, Foltz G, Lin B. "Landscape of the SOX2 protein-protein interactome." Proteomics, 11(5), 921-34, 2011.
  • Fang X, Yoon JG, Li L, Yu W, Shao J, Hua D, Zheng S, Hood L, Goodlett DR, Foltz G, Lin B. "The SOX2 response program in glioblastoma multiforme: an integrated ChIP-seq, expression microarray, and microRNA analysis." BMC Genomics, 12, 11, 2011.
  • Chu LJ, Chen MC, Setter J, Tsai YS, Yang H, Fang X, Ting YS, Shaffer SA, Taylor GK, von Haller PD, Goodlett DR, Ng WV. "New structural proteins of Halobacterium salinarum gas vesicle revealed by comparative proteomics analysis." J Proteome Res, 10(3), 1170-8, 2011.
  • Morris RM, Nunn BL, Frazar C, Goodlett DR, Ting YS, Rocap G. "Comparative metaproteomics reveals ocean-scale shifts in microbial nutrient utilization and energy transduction." ISME J. 2010 Feb 18 [Epub ahead of print].
  • Reiner CL, McCullar JS, Kow RL, Le JH, Goodlett DR, Nathanson NM. "RACK1 associates with muscarinic receptors and regulates M(2) receptor trafficking." PLoS One, 5(10), e13517, 2010.
  • Wilderman PR, Shah MB, Liu T, Li S, Hsu S, Roberts AG, Goodlett DR, Zhang Q, Woods VL Jr, Stout CD, Halpert JR. "Plasticity of cytochrome P450 2B4 as investigated by hydrogen-deuterium exchange mass spectrometry and X-ray crystallography." J Biol Chem, 285(49), 38602-11, 2010.
  • Malmstrom L, Goodlett DR. "Protein structure modeling." Methods Mol Biol, 673, 63-72, 2010.
  • Sanowar S, Singh P, Pfuetzner RA, Andre I, Zheng H, Spreter T, Strynadka NC, Gonen T, Baker D, Goodlett DR, Miller SI. "Interactions of the transmembrane polymeric rings of the Salmonella enterica serovar Typhimurium type III secretion system." MBio, 1(3), 2010.
  • Goo YA, Tsai YS, Liu AY, Goodlett DR, Yang CC. "Urinary proteomics evaluation in interstitial cystitis/painful bladder syndrome: a pilot study." Int Braz J Urol, 36(4), 464-78; discussion 478-9, 479, 2010.

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