University of Washington Research Affiliate Program on Transporters (UWRAPT)

The UWRAPT (University of Washington Research Affiliate program on Transporters) is a cooperate UWRAPT-logoaffiliate program of University of Washington School of Pharmacy, which is established for the purpose of bringing to bear collective expertise and resources to better understand inter-individual variability in pharmacokinetics and pharmacodynamics of drugs by quantifying the absolute expression of transporters in various tissues and cells.

Most recent publications
Wang L, Prasad B, Salphati L, Chu X, Gupta A, Hop CE, Evers R, Unadkat JD. Interspecies Variability in Expression of Hepatobiliary Transporters across Human, Dog, Monkey and Rat as Determined by Quantitative Proteomics. Drug Metab Dispos. 2015 (DOI: dmd.114.061580).This work has been selected as the cover illustration for the March 2015 issue of Drug Metabolism and Disposition.

Kumar V, Prasad B, Patilea G, Gupta A, Salphati L, Evers R, Hop CE, Unadkat JD. Quantitative transporter proteomics by liquid chromatography with tandem mass spectrometry: addressing methodologic issues of plasma membrane isolation and expression-activity relationship. Drug Metab Dispos. 43, 2015, 284.

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